5788
1000+
16
8
613
203
Cat. No. | Product Name | ||
---|---|---|---|
L7870 | 可溶性羧酸片段化合物库 | 1806 compounds | |
可溶性羧酸片段库包含 1806 个化合物 | |||
L6820 | 烟草单体化合物库 | 747 compounds | |
747种烟草单体化合物的独特集合,可用于高通量筛选和高内涵筛选 | |||
L2550 | 谷氨酰胺代谢化合物库 | 565 compounds | |
565 种谷氨酰胺代谢相关的分子,可以用于高通量和高内涵筛选; | |||
L1720 | 核苷类化合物库 | 334 compounds | |
334 种核苷类化合物,包括核苷酸、核苷酸类似物及衍生物等,适用于抗病毒、抗肿瘤、抗真菌、抗抑郁等药物的研发; | |||
L2510 | 脂代谢化合物库 | 492 compounds | |
492 个脂代谢相关的化合物集合,可用于高通量和高内涵筛选; | |||
L2400 | 内分泌激素分子库 | 784 compounds | |
784 种与内分泌系统相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L7000 | 活性脂质化合物库 | 385 compounds | |
385 种生物活性小分子化合物,用于高通量、高内涵筛选; | |||
L2800 | 5-羟色胺分子库 | 268 compounds | |
268 种生物活性小分子化合物,用于高通量、高内涵筛选; | |||
L8710 | 铜死亡化合物库 | 400 compounds | |
TargetMol 铜死亡化合物库集合了 400 种与铜死亡相关的化合物,可以用于铜死亡机制及相关疾病研究 | |||
L3510 | 甲基化化合物库 | 128 compounds | |
128 种甲基化相关的化合物,可以用于高通量和高内涵筛选; | |||
L2140 | 癌细胞分化化合物库 | 406 compounds | |
406 个诱导肿瘤细胞分化化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L2501 | 人内源代谢化合物库 Plus | 1283 compounds | |
1283种内源性生物活性化合物的独特集合,用于高通量、高内涵筛选。 | |||
L3300 | 组胺&褪黑色素化合物库 | 153 compounds | |
153 种生物活性小分子化合物,用于高通量、高内涵筛选; | |||
L2570 | 人代谢物化合物库 | 4454 compounds | |
4454 种人代谢物的独特集合,用于高通量、高内涵筛选; | |||
L6800 | 中国药典收录天然产物库 | 2051 compounds | |
2051 种中国药典收录的天然产物,是药物开发、药理研究等领域的有力工具; | |||
DO2200 | 共价抑制剂库CD | 12000 compounds | |
数量多:超过12000种共价结合化合物,并且数量在持续增加; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
C0104B |
Protein A/G Immunomagnetic Beads
Protein A/G 免疫沉淀磁珠 |
||
C0109 |
Magrose Beads IDA-Nickel
His-tag 蛋白纯化磁珠 IDA-Ni |
||
C0050 |
BCA Protein Quantification Kit
BCA蛋白浓度测定试剂盒 |
Solution in bottle | |
C0104 |
Protein A/G Immunoprecipitation Kit
Protein A/G 免疫沉淀试剂盒 |
||
C0105 |
Protein A Immunoprecipitation Kit
Protein A 免疫沉淀试剂盒 |
||
C0110 |
Magrose Beads IDA-Cobalt
His-tag 蛋白纯化磁珠 IDA-Co |
||
C0111 |
Magrose Beads NTA-Nickel (Ultra-suspension)
His-tag 蛋白纯化磁珠 NTA-Ni |
||
C0003 |
Phosphatase Inhibitor Cocktail II (100× DMSO)
磷酸酶抑制剂 Cocktail II (100× DMSO) |
Solution (100× in DMSO) | Alkaline phosphatases, Ser/Thr phosphatases, <em>Acid</em> and PP1 and PP2A |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9282 |
DBCO-C3-Acid
DBCO-ACID |
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
DBCO-(CH2)3-Acid 是一种用于抗体-药物偶联物的 Click Chemistry 中间体,可用以合成 ADC linker。 | |||
T14184 |
Alkynyl myristic acid
tetradec-13-ynoic acid,13-Tetradecyn-1-oic acid,13-Tetradecynoic acid |
Others; PROTAC Linker | Others; PROTAC |
Alkynyl myristic acid (13-Tetradecyn-1-oic acid) 是一种基于烷基链的 PROTAC 接头。 | |||
T30355 |
Benzeneboronic acid
Phenylboric acid,Phenyldihydroxyborane,Phenylboronic acid |
Others | Others |
Benzeneboronic acid (Phenylboronic acid) 是一种用于Mizuroki Heck 和Suzuki Miyaura 偶联反应的硼酸。 | |||
T32253 |
Jalapinolic acid
11-Hydroxy Palmitic Acid,Builic Acid,Jalapinoic Acid,11-羟基十六酸,11-Hydroxyhexadecanoic acid |
Others | Others |
Jalapinolic acid (Builic Acid) 是一种羟基棕榈酸。 | |||
T19981 |
Rhoduline Acid
Di-J acid,I Acid Imide,NSC 1698 |
||
Rhoduline Acid (Di-J acid)是合成染料的中间体,可用于合成二偶氮染料和四硝唑染料。 | |||
T36522 |
Isoallolithocholic acid
Alloisolithocholic Acid,AILCA,3β-Hydroxy-5α-cholanic acid |
Others | Others |
Isoallolithocholic acid (3β-Hydroxy-5α-cholanic acid) 是一种 T 细胞调节剂,是一种胆汁酸代谢物,具有抗炎活性,与人类免疫稳态有关。 | |||
T19205 |
Benzophenonetetracarboxylic acid
4,4'-Carbonyldiphthalic acid,3,3',4,4'-Benzophenonetetracarboxylic acid |
Others | Others |
Benzophenonetetracarboxylic acid (3,3',4,4'-Benzophenonetetracarboxylic acid) 可用于制备高性能聚酰亚胺,也可用作环氧树脂的固化剂。 | |||
T0755 |
Carglumic Acid
Carbaglu,N-Carbamylglutamate,N-Carbamyl-L-glutamic acid,氨甲酰谷氨酸,Carbamylglutamic acid,Carbamino-L-glutamic acid,Ureidoglutaric acid |
Others | Others |
Carglumic Acid (Ureidoglutaric acid) 是一种 N-乙酰谷氨酸 (NAG) 的功能类似物和氨甲酰磷酸合成酶 1(CPS1)的活化剂,可用于与 N-乙酰谷氨酸合成酶 (NAGS) 缺陷相关的急性和慢性高氨血症的研究。 | |||
T20882 |
4-Nitrobenzoic acid
Kyselina p-nitrobenzoova,4Nitrobenzoic acid,Nitrodracylic acid,4 Nitrobenzoic acid |
||
4-Nitrobenzoic acid (4Nitrobenzoic acid) 是一种药物中间体,常在叶酸、DABA、PABA 和染料的生产中出现。 | |||
T22330 |
Fenamic acid
N-苯基邻氨基苯甲酸,2-Anilinobenzoic acid,Diphenylamine-2-carboxylic acid,2-(Phenylamino)benzoic acid,N-Phenylanthranilic acid |
Chloride channel | Membrane transporter/Ion channel |
Fenamic acid (N-Phenylanthranilic acid) 是氯通道阻滞剂。 | |||
T124384 |
Jasmonic acid
(-)-Jasmonic acid |
||
Jasmonic acid (JA) 是一种植物激素,也是植物生长调节剂,参与植物迫防御和生长发育。Jasmonic acid 在信号传导过程中起着很重要的作用,诱导 MAP 激酶级联通路和钙通道发挥作用。 | |||
T0569 |
Pyrazinoic acid
Pyrazinecarboxylic acid,吡嗪甲酸 |
Others | Others |
Pyrazinoic acid (Pyrazinecarboxylic acid) 是pyrazole thiamethoxam sulfur 的中间体。 | |||
T33868 |
Palmitoyl glutamic acid
N-Palmitoyl-L-glutamic acid,Palmitoylglutaminic acid |
Others | Others |
Palmitoyl glutamic acid (N-Palmitoyl-L-glutamic acid) 是一种酰基氨基酸,可阻断主动脉收缩,可拮抗由氟哌啶醇诱发的口腔运动障碍。Palmitoyl glutamic acid 常常添加在化妆品中。 | |||
T18983 |
DNP-X acid
6-((2,4-Dinitrophenyl)amino)hexanoic acid |
Others | Others |
DNP-X acid (6-((2,4-Dinitrophenyl)amino)hexanoic acid) 是一种与 Trp 或 Tyr 配对的极好的胺反应性 FRET 淬灭剂,能够用于开发可被 anti-DNP 抗体识别的探针的胺反应性构建块。 | |||
T1395 |
Diatrizoic Acid
Diatrizoate,泛影酸,Amidotrizoic acid |
Apoptosis; Others | Apoptosis; Others |
Diatrizoic Acid (Amidotrizoic acid) 是一种有机碘化不透射线 X 射线造影剂,用于放射诊断,具有对气道进行放射照相成像的潜力。它通过钙失调诱导线粒体更新和氧化应激,激活细胞凋亡。 | |||
T64387 |
2-Nitrobenzoic acid
o-Nitrobenzoic acid |
Others | Others |
2-Nitrobenzoic acid (o-Nitrobenzoic acid) 是一种抗增殖化合物,对表达 T 型钙通道α1H 或其剪接变体δ25的 jurkat 细胞系显示出8.3μM 的 IC50。 | |||
T22348 |
Isonipecotic acid
4-Piperidinecarboxylic acid,Hexahydroisonicotinic acid,4-哌啶甲酸,4-Carboxypiperidine |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Isonipecotic acid (4-Piperidinecarboxylic acid) 是一种杂环化合物。它主要表征为 GABAA 受体部分激动剂。 | |||
T20841 |
Nitrilotriacetic acid
Triglycollamic acid,Nitrilotriacetate,Nitriloacetate |
Others | Others |
Nitrilotriacetic acid (Nitriloacetate) 是一种螯合剂,可与二价金属离子介导的6His标签反应来跟踪和富集活细胞中的His标签蛋白。 | |||
T35684 |
2-Hydroxystearic acid
2-Hydroxy stearic acid,DL-2-Hydroxystearic acid |
||
2-Hydroxystearic acid 是一种从人类和 U. armoricana 中发现的羟基脂肪酸。当使用浓度为 100 μM 时,它能减少艾氏腹水瘤(EAT)细胞在体外的生长。 | |||
T1592 |
Acetohydroxamic acid
Methylhydroxamic acid,Acetic acid,Lithostat,AHA,oxime,N-Hydroxyacetamide,乙酰氧肟酸 |
MMP; Antibacterial | Microbiology/Virology; Proteases/Proteasome |
Acetohydroxamic acid (N-Hydroxyacetamide) 是一种不可逆的细菌和植物尿素酶抑制剂,可研究慢性尿路感染。 | |||
T21233 |
Dihydrolipoic acid
Reduced thioctic acid,Reduced lipoic acid,DHLA,USAF XR-12,6,8-Dihydrothioctic acid,二氢硫辛酸 |
Antioxidant | oxidation-reduction |
Dihydrolipoic acid (USAF XR-12) 是高效的抗氧化剂,对所有以氧为中心的自由基都有很强的清除能力。它在多种疾病中表现出抗炎特性。在 LPS 诱导的疾病行为大鼠中,它通过 ERK/Nrf2/HO-1/ROS/NLRP3 通路发挥预防作用。它还可以可用于抑郁症的研究。 | |||
T37681 |
3-hydroxy Stearic Acid
3-hydroxystearic acid,3-hydroxyoctadecanoic acid |
||
3-hydroxy Stearic Acid (3-hydroxystearic acid) 是从假单胞菌和菌丝桃属植物中发现的一种脂肪酸。 | |||
T0629 |
Atropic acid
2-苯基丙烯酸,Acrylic acid |
Others | Others |
Atropic acid (Acrylic acid) 是 Ipratropium bromide 和 Atropine Sulfate 的杂质。 | |||
T0061 |
Clofibric acid
Chlorofibrinic acid,氯贝酸 |
PPAR; Drug Metabolite | DNA Damage/DNA Repair; Metabolism |
Clofibric acid (Chlorofibrinic acid) 是一种脂质纤维调节剂 Clofibrate,Etofibrate 和 Etofyllinclofibrate 的活性代谢物,是 PPARα的激动剂,具有降血脂作用,也可作为除草剂。 | |||
T5443 |
JQ-1 (carboxylic acid)
JQ-1 carboxylic acid |
Epigenetic Reader Domain | Chromatin/Epigenetic |
JQ-1 (carboxylic acid) 是一种细胞渗透性 BRD4 抑制剂,对 BRD4(1) 和 BRD4(2) 的 IC50 分别为 77 和 33 nM。它是一种 (+)-JQ1 衍生物,可作为合成 PROTACs 的前体。 | |||
T0960 |
Iopanoic acid
碘番酸,Iodopanoic acid,Acidum iopanoicum |
Others | Others |
Iopanoic acid 是一种碘造影剂,也是一种 5'-Deiodinase 抑制剂。 | |||
T37992 |
15-Methyl Palmitic Acid
15-Methylpalmitic acid,15-Methylhexadecanoic acid |
||
15-methyl Palmitic Acid 是一种一种甲基化脂肪酸,广泛存在于动物脂质中,可能于调节脂肪代谢有关。 | |||
T19415 |
Medronic acid
亚甲基二磷酸,Methylenediphosphonic acid |
Others | Others |
Medronic acid (Methylenediphosphonic acid) 是一种亚甲基取代的二膦酸盐。它对骨基质中的羟基磷灰石晶体的表面具有亲和力,并且可粘附在其表面。它能够在类骨质矿化的位点累积,可以在骨成像中与放射性同位素复合使用。 | |||
T11599 |
Ibiglustat (L-Malic acid)
Ibiglustat L-Malic acid,GZ402671 (L-Malic acid),Venglustat (L-Malic acid),SAR402671 (L-Malic acid) |
Transferase | Metabolism |
Ibiglustat (L-Malic acid) (Ibiglustat L-Malic acid) 是一种选择性的、脑渗透性的和别构的葡萄糖神经酰胺合酶抑制剂。 Ibiglustat (L-Malic acid) 可用于关于 PD 帕金森病、法布里和戈谢氏 SRT 的研究。 | |||
T0580 |
4-Pentynoic acid
Propargylacetic acid,戊炔酸 |
Others | Others |
4-Pentynoic acid (Propargylacetic acid) 已用于与 1-溴-1-炔烃在 Pd 催化剂存在下的反应,产生具有生物活性的烯醇内酯。它还用于通过双乙炔的闭环复分解合成具有细胞毒性的大环内酯。 | |||
T37547 |
trans-Urocanic Acid
trans-UCA,(E)-Urocanic acid |
||
trans-Urocanic Acid ((E)-Urocanic acid) 是一种主要分布于海马体和前额叶皮层的化合物,是顺式UCA的异构体,是表皮紫外线保护剂,可增强替诺福韦艾拉酚胺在长效HIV应用中的稳定性。trans-urocanic acid 可有效调节免疫功能,可在体外抑制人类自然杀伤细胞的活性,可用于研究阿尔茨海默病。 | |||
T37994 |
16-hydroxy Hexadecanoic Acid
Juniperic acid |
||
16-hydroxy Hexadecanoic Acid (Juniperic acid) 是从拟南芥叶和茎中分离出的化合物,可用于预防、缓解或治疗代谢性疾病。 | |||
T1296 |
4-Aminosalicylic acid
Aminosalicylic acid,4-aminosalicylate,para-aminosalicylic acid,对氨水杨酸,Aminopar |
NF-κB; Lipoxygenase; COX; Glutathione Peroxidase; Antibacterial; Antibiotic | Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; NF-κB |
4-Aminosalicylic acid (para-aminosalicylic acid) 是一种具有口服活性的抗生素,可研究肺结核病。 | |||
T10824 |
cis-Urocanic acid
cis-UCA,(Z)-Imidazole-4-acrylic acid,(Z)-Urocanic acid,(E)-Urocanic acid,(Z)-3-(1H-Imidazol-5-yl)acrylic acid,顺式-尿刊酸 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
cis-Urocanic acid ((E)-Urocanic acid) 是一种 5-HT2A 受体激动剂,cis-Urocanic acid 与 5-HT 受体结合的Kd 为 4.6 nM。cis-Urocanic acid 是一种免疫调节剂,通过与 5-HT2A 受体结合而诱导免疫抑制。 | |||
T15478 |
Hexane-1,6-diyldiphosphonic acid
1,6-Hexanebisphosphonic acid |
||
Hexane-1,6-diyldiphosphonic acid (1,6-Hexanebisphosphonic acid) 是一种基于烷基链的 PROTAC linker。 | |||
T0666 |
4-Chlorosalicylic acid
4-Chloro-2-hydroxybenzoic acid, 4-chloro salicylic acid,4-氯水杨酸 |
Tyrosinase; Antibacterial; Antibiotic; Antifungal | Microbiology/Virology; Proteases/Proteasome |
4-Chlorosalicylic acid (4-Chloro-2-hydroxybenzoic acid, 4-chloro salicylic acid) 是一种药物中间体。它抑制单酚酶和二苯酚酶活性,IC50值分别为1.89 mM 和1.10 mM。 它有抗菌活性,抑制大肠杆菌的MIC 为250 μg/mL,MBC 为500 μg/mL。 | |||
T20470 |
Edetic acid
Ethylenediaminetetraacetic acid,乙二胺四乙酸,EDTA |
Others | Others |
Edetic acid (Ethylenediaminetetraacetic acid) 是 Edetate 的酸形式,是一种具有抗高钙血症和抗凝血特性的螯合剂。它与钙和重金属离子结合后,会形成可溶的稳定复合体,使血清钙水平降低。它也可用作血液样本的抗凝剂,并用于治疗铅中毒。 | |||
T20881 |
2-Iodobenzoic acid
o-Iodobenzoic acid,2-碘苯甲酸,Kyselina o-jodbenzoova,2Iodobenzoic acid |
Others | Others |
2-Iodobenzoic acid (o-Iodobenzoic acid) 是合成 Dess-Martin periodinane 的冲击敏感中间体。 | |||
T4564 |
Ethacrynic acid
Edecrin,利尿酸,Etacrynic Acid,Hydromedin |
Others; Calcium Channel; NF-κB; GST | Membrane transporter/Ion channel; Metabolism; NF-κB; Others; oxidation-reduction |
Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂,也是NF-κB 信号传导途径的有效抑制剂,并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道,从而导致气道平滑肌细胞松弛。它是利尿剂,具有抗炎特性,可减轻类维生素 A 诱导的小鼠耳部水肿。 | |||
T20362 |
Glutamyl-glutamic acid
Glu-glu,Dipotassium glutamyl-glutamate,N-L-alpha-Glutamyl-L-glutamic acid |
Amino Acids and Derivatives | Metabolism |
Glutamyl-glutamic acid (Glu-glu) 是一些微球菌和节杆菌属菌的胞壁中的肽桥。 | |||
T1423 |
3-Methylsalicylic acid
Hydroxytoluic acid,3-甲基水杨酸,o-Cresotic acid,邻甲基水杨酸 |
COX | Immunology/Inflammation; Neuroscience |
3-Methylsalicylic acid (o-Cresotic acid) 是水杨酸衍生物,可作用于人血浆,激活纤维蛋白溶解系统,具有显著的纤溶活性。 | |||
T25918 |
Palmitoyl-L-aspartic acid
L-N-Palmitoylaspartic acid |
Others | Others |
Palmitoyl-L-aspartic acid is a natural N-acylaspartate that suppresses Hedgehog signaling after stimulation with Smoothened agonist or non-sterol-modified Sonic Hedgehog. It does not alter the activity of cannabinoid receptors or fatty acid amide hydrolas | |||
T20506 |
Maleuric acid
N-Carbamoylmaleamic acid,AI3 32778,AI3-32778,AI332778 |
Others | Others |
Maleuric acid (N-Carbamoylmaleamic acid) 可抗有丝分裂,可与放射自显影技术结合起来用于生物研究。Maleuric acid 可用于改善动植物的生长和繁殖力以及治疗乳清酸缺乏症。 | |||
T65133 |
3-Hydroxybutyric acid sodium
β-Hydroxybutyric acid sodium |
Others | Others |
3-Hydroxybutyric acid sodium (β-Hydroxybutyric acid sodium) 是一种存在 I 型糖尿病患者体内的一种代谢物,具有调节膜脂的性质。 | |||
T0067 |
Nicotinic acid N-oxide
烟酸-N-氧化物,Nicotinic acid 1-oxide,氧烟酸,Oxiniacic Acid |
Others | Others |
Nicotinic acid N-oxide (Nicotinic acid 1-oxide) 是一种烟酸衍生物,用于治疗高脂血症。 | |||
T1691 |
4-Formylbenzoic acid
对醛基苯甲酸,Benzoic acid |
Others | Others |
4-Formylbenzoic acid (Benzoic acid) 可用作医药、农药、荧光增白剂的中间体。 | |||
T36624L |
α-Hydroxyglutaric Acid Lithium
α-Hydroxyglutaric Acid Lithium(2889-31-8 Free base) |
Decarboxylase; Endogenous Metabolite; mTOR | Metabolism; Others; PI3K/Akt/mTOR signaling |
α-Hydroxyglutaric Acid Lithium 在微生物和动物体内有谷氨酸转化而来,是 α-酮戊二酸依赖性双加氧酶和 5-甲基胞嘧啶羟化酶抑制剂,对 ATP 合酶和 mTOR 信号传导有抑制作用。 | |||
TQ0147 |
Arundic Acid
ONO 2506,(R)-2-丙基辛酸,(R)-2-Propyloctanoic acid |
Others | Others |
Arundic Acid (ONO 2506) 是星形胶质细胞调节剂,能够抑制 S-100β 的合成,并调节星形胶质细胞的活化,进而延缓脑梗塞的扩张。 它对中风和阿尔茨海默病具有潜在的研究价值。 | |||
T68019L |
Ursulcholic acid trisodium salt
Ursodeoxycholic acid disulfate trisodium salt,Ursulcholic acid trisodium salt(88426-32-8 Free base) |
Others | Others |
Ursulcholic acid trisodium salt (Ursodeoxycholic acid disulfate trisodium salt) 是 ursodeoxycholic acid 的可溶形式,ursodeoxycholic acid 具有抗高血脂和利胆活性活性。 | |||
T1402 |
Fenofibric acid
非诺贝特酸,Trilipix,FNF acid,NSC 281318 |
MMP; COX; PPAR | DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Neuroscience; Proteases/Proteasome |
Fenofibric acid (FNF acid) 是 fenofibrate 的活性代谢物,是PPAR 激动剂,对 PPARα、PPARγ 和 PPARδ 的EC50值分别为 22.4、1.47 和 1.06 µM。它抑制COX-2的活性,IC50值为 48 nM。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3391 |
Corosolic acid
Corsolic acid,2α-Hydroxyursolic acid,科罗索酸,Glucosol,Colosolic acid,Colosic acid |
FAK; Autophagy | Angiogenesis; Autophagy; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors |
Corosolic acid (Colosic acid) 是从大花紫薇中提取的一种天然产物,具有抗肿瘤活性。 | |||
T2P2923 |
Stearic acid
硬脂酸,Isostearic acid,Octadecanoic acid,Cetylacetic acid |
Phosphatase; Endogenous Metabolite | Metabolism |
Stearic acid (Cetylacetic acid) 是长链饱和脂肪酸,存在于许多动植物油脂中。 | |||
T6873 |
Lauric Acid
月桂酸,Dodecylic acid,dodecanoic acid,Vulvic acid,N-Dodecanoic acid |
Others; Endogenous Metabolite; Antibacterial | Metabolism; Microbiology/Virology; Others |
Lauric Acid (Dodecylic acid) 是一种有抗菌活性的中链脂肪酸,对P. acnes,S.aureus 和S. epidermidis 的 EC50值分别为 2,6,4 μg/mL。 | |||
T2719 |
Succinic acid
Asuccin,Amber acid,琥珀酸,1,2-Ethanedicarboxylic acid,Wormwood acid,Butanedioic acid,1,4-Butandioic Acid |
Endogenous Metabolite | Metabolism |
Succinic acid (1,2-Ethanedicarboxylic acid) 是无氧代谢的发酵产物,也是三羧酸循环的中间产物。 | |||
T3379 |
Decanoic Acid
Decoic acid,CAPRIC ACID,Caprynic acid,癸酸 |
GluR; iGluR | Membrane transporter/Ion channel; Neuroscience |
Decanoic Acid (Caprynic acid) 是中链甘油三酯中的成分,是非竞争性和可透过血脑屏障的 AMPA 受体抑制剂,具有抗癫痫作用。 | |||
T5291 |
Malonic acid
Carboxyacetic Acid,1,3-Propanedioic Acid,丙二酸,Propanedioic Acid |
Others | Others |
Malonic acid (propanedioic acid) 是竞争性抑制剂的典型例子:它作用于呼吸电子传递链中的琥珀酸脱氢酶(复合物 II)。发现丙二酸与丙二酰辅酶A 脱羧酶缺乏有关,这是一种先天性代谢错误。 | |||
T2877 |
Mucic Acid
Galactaric acid,Saccharolactic acid,Schleimsaure,粘液酸,D-Glucaric acid,Tetrahydroxyadipic acid |
Others; Endogenous Metabolite | Metabolism; Others |
Mucic Acid (Tetrahydroxyadipic acid) 是内源性代谢产物的一种。 | |||
TN7057 |
rosmarinate acid
(R)-rosmarinic acid,rosmarinic acid,迷迭香素,Rosemary acid |
MAO; Endogenous Metabolite; Transferase | Metabolism; Neuroscience |
Rosmarinate acid(Rosemary acid) 抑制 MAO-A、MAO-B 和 COMT 酶,IC50 分别为 50.1、184.6 和 26.7 μM。 | |||
T3947 |
Nonanoic acid
pelargonic acid,Nonoic acid,壬酸 |
Others; Antibacterial | Microbiology/Virology; Others |
Nonanoic acid (Nonoic acid) 是一种天然存在的具有九个碳原子的饱和脂肪酸。它减少细菌易位,增强抗菌活性,并增加猪 β-防御素 1 (pBD-1) 和 pBD-2 的分泌。 | |||
T19124 |
3-Oxocholic acid
3-Ketocholic acid |
Endogenous Metabolite | Metabolism |
3-Oxocholic acid(3-Ketocholic acid) 是胆汁酸的代谢产物,也是产气荚膜梭菌在肠道中由胆汁降解的主要产物。33-Oxocholic acid 是一种主要存在于哺乳动物的胆汁中类固醇酸。 | |||
T35673 |
Stictic Acid
Scopularic acid |
Others | Others |
Stictic Acid (Scopularic acid) 分离自苏门答腊地衣 Stereocaulon montagneanum,可抑制 HT-29 人结肠腺癌细胞的生长,IC50 为 29.29 μg/ml。 | |||
T5609 |
Isovaleric acid
3-Methylbutyric acid,Isopentanoic acid,β-methylbutyric acid,异戊酸,3-Methylbutanoic acid,Delphinic acid |
Others; Endogenous Metabolite | Metabolism; Others |
Isovaleric acid (Delphinic acid) 是天然脂肪酸,可能与人类新生儿死亡以及牙买加呕吐病有关。 | |||
T3090 |
Abietic Acid
Rosin Acid,L-Abietic acid,Sylvic acid,松香酸,Abietate |
MMP; Lipoxygenase; Antibacterial; PPAR | DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; Proteases/Proteasome |
Abietic Acid (Sylvic acid) 是从 Pimenta racemosavar. grissea 中提取出来的一种二萜,具有抗菌、抗增殖和抗肥胖的活性。它抑制脂氧合酶活性,可研究过敏性疾病。 | |||
T75319 |
Taurodeoxycholic acid
Taurodeoxychloic acid |
Apoptosis; Calcium Channel; Caspase | Apoptosis; Membrane transporter/Ion channel; Metabolism; Proteases/Proteasome |
Taurodeoxycholic acid (Taurodeoxychloic acid) 是脱氧胆酸的胆汁酸牛磺酸共轭物,是一种人体代谢物,可稳定线粒体膜,减少自由基形成。Taurodeoxycholic acid 通过阻断钙介导的凋亡通路以及 Caspase-12 激活来抑制凋亡 (apoptosis)。Taurodeoxycholic acid具有神经保护活性,可用于研究 3-硝基丙酸诱导或稳定遗传的亨廷顿舞蹈病 (HD) 。 | |||
T3950 |
Tridecanoic acid
n-Tridecoic Acid,n-Tridecanoic Acid,十三酸,Tridecylic Acid |
Others; Endogenous Metabolite; Antibacterial | Metabolism; Microbiology/Virology; Others |
Tridecanoic acid (Tridecylic Acid) 是一种存在于乳制品中的 13 碳饱和脂肪酸,也是正十六烷厌氧生物降解的产物。 它是磷脂酶 A2 的底物,可作为抗粘剂和抗生物膜剂,用于研究细菌感染。它抑制大肠杆菌的持久性和生物膜形成。 | |||
T4S1452 |
Artemisic acid
(+)-Artemisinic Acid,青蒿酸,Artemisinic acid |
Antibacterial | Microbiology/Virology |
Artemisic acid ((+)-Artemisinic Acid) 是黄花蒿中分离得到的一种倍半萜,具有多种药理活性,如抗疟、抗菌和抗肿瘤活性,以及解热、化感和抗脂肪生成作用。 | |||
T2S0850 |
Malic acid
E 296,苹果酸,2-Hydroxysuccinic acid,Hydroxybutanedioic acid,FDA 2018,Deoxytetraric acid,Pomalus acid |
Others; Endogenous Metabolite | Metabolism; Others |
Malic acid (Pomalus acid) 是一种天然存在于水果中的二羧酸,如苹果和梨。Malic acid 在许多酸味或酸味食物中起作用。 | |||
T5542 |
Tiglic acid
惕格酸,Sabadillic acid,Tiglinic acid,巴豆酸,Cevadic acid |
Endogenous Metabolite; HSV | Metabolism; Microbiology/Virology |
Tiglic acid 是一种存在于巴豆油和其他几种天然产物中的单羧酸不饱和有机酸。它具有植物代谢物的作用。 | |||
T4775 |
Arachidic acid
eicosanoic acid,Icosanoic Acid,花生酸 |
Others; Endogenous Metabolite | Metabolism; Others |
Arachidic acid (Icosanoic Acid) 是一种存在于所有哺乳动物细胞中的长链脂肪酸,通常酯化为膜磷脂,是人体组织中丰富的多不饱和脂肪酸之一。 | |||
T4885 |
(-)-Aspartic acid
(R)-Aspartic acid,Asp,D-(-)-Aspartic acid,D-天门冬氨酸,Aminosuccinic acid,asparagic acid,L-Homoproline,D-Aspartic acid |
Endogenous Metabolite; NMDAR; iGluR | Membrane transporter/Ion channel; Metabolism; Neuroscience |
(-)-Aspartic acid (L-Homoproline) 是一种存在于无脊椎动物和脊椎动物中的内源性氨基酸,是 NMDA 受体激动剂,可调节睾酮合成。 | |||
T2215 |
Ferulic Acid
Coniferic acid,Fumalic Acid,阿魏酸 |
FGFR; Endogenous Metabolite | Angiogenesis; Metabolism; Tyrosine Kinase/Adaptors |
Ferulic Acid (Coniferic acid) 是新型的成纤维细胞生长因子受体 1 (FGFR1)抑制剂, 在FGFR1和FGFR2的IC50分别为 3.78 和 12.5 μM。 | |||
T4804 |
Pyruvic acid
BTS,Pyroracemic acid,α-Ketopropionic acid,2-Oxopropionic acid,Acetylformic acid,丙酮酸,NSC 179 |
Others; Endogenous Metabolite | Metabolism; Others |
Pyruvic acid (Acetylformic acid) 是碳水化合物,是蛋白质和脂肪代谢的中间产物。 | |||
T2908 |
Palmitic acid
Hexadecoic acid,hexadecanoic acid,棕榈酸,Cetylic acid |
HSP; Endogenous Metabolite | Cytoskeletal Signaling; Metabolism |
Palmitic acid (Cetylic acid) 属于天然产物,是一种常见的饱和脂肪酸,在动物、植物和微生物中均存在。Palmitic acid 具有抗肿瘤活性。 | |||
T13505 |
3α,12β-Dihydroxycholanoic acid
Lagodeoxycholic acid |
Endogenous Metabolite | Metabolism |
3α,12β-Dihydroxycholanoic acid (Lagodeoxycholic acid) 是一种广泛存在于动物体内的胆汁酸。 | |||
T5S0018 |
Betulonic acid
路路通酸,(+)-Betulonic acid,Betunolic acid,Liquidambaric acid |
Parasite; HSV | Microbiology/Virology |
Betulonic acid (Liquidambaric acid) 是一种在许多植物中存在的三萜类天然产物,具有抗肿瘤,抗炎,抗寄生虫和抗病毒的活性。 | |||
T3772 |
Maslinic acid
2α-Hydroxyoleanoic Acid,山楂酸,2α-Hydroxyoleanolic acid,Crategolic acid |
NF-κB; HIV Protease; DNA/RNA Synthesis; Antibacterial | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; NF-κB; Proteases/Proteasome |
Maslinic acid (Crategolic acid) 是一种 DNA 聚合酶 B 抑制剂,抑制 NF-κB p65的 DNA 结合活性并消除 IκB-α磷酸化。 | |||
T2827 |
Asiatic acid
Asiantic acid,Dammarolic acid,积雪草酸 |
Apoptosis; p38 MAPK; Parasite | Apoptosis; MAPK; Microbiology/Virology |
Asiatic acid (Dammarolic acid) 是在Centella asiatica 中发现的一种五环三萜,有抗炎活性,可诱导黑色素瘤细胞的凋亡,有可能治疗皮肤癌。 | |||
T3S0507 |
Homovanillic acid
Homovaniuic acid,Vanilacetic acid,高香草酸,Vanillacetic acid |
Others; Endogenous Metabolite | Metabolism; Others |
Homovanillic acid (Vanillacetic acid) 是一种多巴胺代谢物,它与乳糜泻、生长激素缺乏、芳香族氨基酸脱羧酶缺乏症以及脂联素还原酶缺乏症相关。 | |||
T4734 |
Suberic acid
Octanedioic acid,1,8-Octanedioic acid,辛二酸 |
Others; Endogenous Metabolite | Metabolism; Others |
Suberic acid (1,8-Octanedioic acid) 被发现和肉毒碱-甲酰基-丙氨酸转位酶缺乏(丙二醇-羧基酶缺乏症)有关。 | |||
T3753 |
Sinapinic Acid
Sinapic acid,芥子酸,Synapoic acid |
Apoptosis; RAAS; Reactive Oxygen Species; HDAC | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Endocrinology/Hormones; Immunology/Inflammation; Metabolism; NF-κB |
Sinapinic Acid (Synapoic acid) 是从 Hydnophytum formicarumJack. 根中分离到的酚类,是HDAC 抑制剂,对ACE-I 的活性也有抑制作用。它有抗肿瘤活性,诱导肿瘤细胞凋亡,具有抗氧化、抗糖尿病的作用。 | |||
T5252 |
Tridecanedioic acid
十三烷二酸,1,11-Undecanedicarboxylic acid,1,13-Tridecanedioic acid,Brassilic acid |
Others; Endogenous Metabolite | Metabolism; Others |
Tridecanedioic acid (Brassilic acid) 是内源性代谢产物的一种。 | |||
T5551 |
Levulinic acid
β-Acetylpropionic acid,4-Oxovaleric acid,Laevulinic acid,乙酰丙酸 |
Others; Endogenous Metabolite | Metabolism; Others |
Levulinic acid (4-Oxovaleric acid) 是一种合成生物燃料的前体。 | |||
T3732 |
Decanedioic acid
1,10-Decanedioic acid,皮脂酸,Sebacic acid,Sebacinsaure,1,8-Octanedicarboxylic acid |
HIV Protease; Endogenous Metabolite | Metabolism; Microbiology/Virology; Proteases/Proteasome |
Decanedioic acid (Sebacinsaure) 是普通尿酸,与肉毒碱-甲酰乙胺转运酶缺乏和中链酰辅酶缺乏症有关。 | |||
T10584 |
Bovinic acid
(9Z,11E)-Octadecadienoic acid,Rumenic acid |
Endogenous Metabolite | Metabolism |
Bovinic acid ((9Z,11E)-Octadecadienoic acid) 是一种具有抗癌和抗动脉硬化的活性的共轭亚油酸,可用于研究老年冠心病和肥胖。 | |||
TN6722 |
Terminolic acid
2α,6β,23-trihydroxyl oleanolic acid |
Antibacterial | Microbiology/Virology |
Terminolic acid (2α,6β,23-trihydroxyl oleanolic acid) 是一种从 Combretum racemosum 中分离得到的五环三萜糖苷,可通过与 IL-1β 和 IL-6 的受体活性位点结合抑制促炎细胞因子,并通过与 IL-4 受体结合位点结合增强抗炎细胞因子。它还表现出适度的抗菌活性。 | |||
T35792 |
Isolithocholic Acid
3-Epilithocholic acid,3β-Hydroxy-5β-cholanic acid,β-Lithocholic acid,isoLCA |
Endogenous Metabolite | Metabolism |
Isolithocholic Acid (3-Epilithocholic acid) (β-Lithocholic acid) 是石胆酸的一种同分异构体。Isolithocholic Acid 是一种胆酸,由 Lithocholic acid 或 Lithocholic acid 3α-sulfate 经微生物代谢形成。 | |||
T5564 |
Tricarballylic acid
β-Carboxyglutaric acid,1,2,3-Propanetricarboxylic acid,三碳烯丙酸,Carballylic acid,Propane-1,2,3-tricarboxylic acid,丙三酸 |
aconitase; Mitochondrial Metabolism | Metabolism |
Tricarballylic acid (Carballylic acid) 是三碳烯丙酸酯的共轭酸,是一种乌头酸水合酶的竞争性抑制剂,其 Ki= 0.52 mM。 | |||
T5558 |
Chelidonic acid
Jervaic acid,Jerva acid,白屈菜酸,γ-Pyrone-2,6-dicarboxylic acid |
NF-κB; Caspase | Apoptosis; NF-κB; Proteases/Proteasome |
Chelidonic acid (Jervaic acid) 是从白屈菜中分到的酸类物质,用作温和的镇痛剂、抗菌剂和中枢神经系统镇静剂。它是谷氨酸脱羧酶抑制剂,Ki 值为 1.2 μM。它可能通过抑制 NF-κB 和caspase-1来降低 IL-6 的产生抗炎作用。 | |||
T20191 |
(-)-Camphoric acid
(-)-樟脑酸,L-Camphoric acid,Camphoric acid, (-)- |
GluR | Neuroscience |
(-)-Camphoric acid (L-Camphoric acid) 是一种活性较低的樟脑酸对映异构体,樟脑酸可诱导 GluR 表达。 | |||
T3948 |
Undecanoic acid
Hendecanoic acid,十一烷酸,Undecylic acid |
Others; Endogenous Metabolite; Antifungal | Metabolism; Microbiology/Virology; Others |
Undecanoic acid (Hendecanoic acid) 是一种具有抗真菌特性的一元羧酸,可抑制红色葡萄球菌中细胞外角蛋白酶、脂肪酶的产生和几种磷脂的生物合成。 | |||
TCS2070 |
Homogentisic acid
高龙胆酸,2,5-dihydroxyphenylacetic acid,Homogentisinic Acid,Melanic acid |
Antioxidant; Endogenous Metabolite | Metabolism; oxidation-reduction |
Homogentisic acid (2,5-dihydroxyphenylacetic acid) 是一种尿液和血清代谢物中的特定代谢物,可用于尿黑酸尿症的诊断。 | |||
T4795 |
Pimelic acid
Pileric acid,1,7-Heptanedioic acid,庚二酸,1,5-Pentanedicarboxylic acid |
Others; Endogenous Metabolite | Metabolism; Others |
Pimelic acid (1,5-Pentanedicarboxylic acid) 的衍生物能够参与赖氨酸的生物合成。 | |||
T5237 |
Hexadecanedioic acid
1,14-Tetradecanedicarboxylic acid,1,16-Hexadecanedioic acid,Thapsic acid,十六碳二酸 |
Others; Endogenous Metabolite | Metabolism; Others |
Hexadecanedioic acid (1,16-Hexadecanedioic acid) 能够与 Sepharose 4B 以共价键结合,比染料树脂更具有特异性,用于去除血浆中的血清白蛋白。 | |||
TQ0279 |
Ibotenic acid
(+/-)-Ibotenic acid,DL-Ibotenic acid,Ibotenate,鹅膏氨酸,(RS)-Ibotenic acid |
NMDAR | Neuroscience |
Ibotenic acid (RS-42358-197) 对 N-甲基-D-天冬氨酸 (NMDA) 和反式-ACPD 或代谢型使君子氨酸 (Qm) 受体位点具有激动剂活性。 | |||
T2O2668 |
Oleic acid
Elaidoic acid,9Z-Octadecenoic acid,Oleate,9-Octadecenoic Acid,Glycon Wo,9-cis-Octadecenoic acid,油酸 |
Apoptosis; ATPase; Others; Endogenous Metabolite | Apoptosis; Membrane transporter/Ion channel; Metabolism; Others |
Oleic acid (Glycon Wo) 属于天然产物,是一种常见的不饱和脂肪酸,在存在于多种动物、植物的脂肪和油脂中。Oleic acid 是一种 Na+/K+ATP 酶激活剂。 | |||
T0558 |
Dihydroferulic acid
Dihydroconiferylic acid,氢化阿魏酸,Hydroferulic acid |
Others | Others |
Dihydroferulic acid 是一种姜黄素的主要代谢产物,具有抗氧化/清除自由基的活性,其IC50=19.5 μM。它是香草酸的前体物质,也是人类肠道菌群的代谢产物。 | |||
T19284 |
Dimethylmalonic acid
2,2-Dimethylmalonic acid |
Endogenous Metabolite | Metabolism |
Dimethylmalonic acid(2,2-Dimethylmalonic acid) 是人血清中的短链二羧酸,可用于预防或延缓鱼肌动球蛋白在冷冻缓冲溶液(pH 7)中的变性。 | |||
T3763 |
Fumaric acid
Lichenic acid,Fumarate,2-Butenedioic acid,Trans-Butenedioic acid,反丁烯二酸,Donitic acid,Allomaleic acid,富马酸 |
Endogenous Metabolite | Metabolism |
Fumaric acid (2-Butenedioic acid) 与烟酸酶缺乏症相关,是癌症相关的内源性代谢物。 | |||
TL0006 |
Cichoric Acid
菊苣酸,Dicaffeoyltartaric acid,Chicoric Acid |
Reactive Oxygen Species; HIV Protease | Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome |
Cichoric Acid (Dicaffeoyltartaric acid) 是一种天然化合物,具有抗氧化作用。 | |||
T3744 |
Veratric acid
Veratrumenoic acid,藜芦酸,3,4-Dimethoxybenzoic acid |
Reactive Oxygen Species; COX | Immunology/Inflammation; Metabolism; Neuroscience; NF-κB |
Veratric acid (3,4-Dimethoxybenzoic acid) 是从蔬菜和水果中得到的一种可口服多酚,具有抗氧化、保护心血管和抗炎活性。当细胞受到 UVB 辐射时,它能够减少上调的 COX-2 表达,降低 PGE2 和 IL-6 水平。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02131 |
Acid Phosphatase/ACP1 Protein, Human, Recombinant (GST)
acid phosphatase 1, soluble,HAAP |
Human | E. coli |
The low molecular weight phosphotyrosine phosphatase (LMW-PTP), also known as Acid phosphatase 1 (ACP1), belongs to the low molecular weight phosphotyrosine protein phosphatase family are involved in the regulation of important physiological functions, including stress resistance and synthesis of the polysaccharide capsule. ACP1/LMW-PTP is an enzyme involved in platelet-derived growth factor-induced mitogenesis and cytoskeleton rearrangement. LMW-PTP is able to specifically bind and dephosphoryl... | |||
TMPY-00367 |
Chemerin/RARRES2 Protein, Mouse, Recombinant (His)
AI303516,retinoic acid receptor responder (tazarote... |
Mouse | HEK293 Cells |
Chemerin/RARRES2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is Q9DD06. | |||
TMPY-02155 |
Prostatic Acid Phosphatase Protein, Human, Recombinant (His)
5'-NT,acid phosphatase, prostate,PAP,ACP-3,ACP3 |
Human | HEK293 Cells |
Prostatic Acid Phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42 kDa and the accession number is P15309-2. | |||
TMPY-02672 |
Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His)
5'-NT,9.104100899-104272570.1,Ppal,A030005E02Rik,PAP,Lap, |
Mouse | HEK293 Cells |
Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42 kDa and the accession number is Q8CE08-1. | |||
TMPY-02585 |
Acid sphingomyelinase/SMPD1 Protein, Mouse, Recombinant (His)
aSMase,ASM,Zn-SMase,A-SMase,sphingomyelin phosphodiesterase ... |
Mouse | Baculovirus Insect Cells |
Sphingomyelin phosphodiesterase 1 (SMPD1) , also known as ASM ( acid sphingomyelinase ), is a member of the acid sphingomyelinase family of enzymes. Three isoforms have been identified, isoform 1 is 631 amino acids (aa) in length as the pro form, while Isoform 2 and isoform 3 have lost catalytic activity. The active SMPD1 isoform 1 contains one saposin B-type domain that likely interacts with sphingomyelin, and a catalytic region. Human SMPD1 is 86% aa identical to mouse SMPD1. SMPD1 is a monome... | |||
TMPY-05526 |
Siglec-15 Protein, Human, Recombinant (His)
SIGLEC-15,sialic acid binding Ig-like lectin 15,CD3... |
Human | HEK293 Cells |
Siglec-15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.7 kDa and the accession number is Q6ZMC9-1. | |||
TMPY-05658 |
Siglec-10 Protein, Human, Recombinant (His)
sialic acid binding Ig like lectin 10,SLG2,PRO940,S... |
Human | HEK293 Cells |
Siglec-10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.5 kDa and the accession number is AAI01726.1. | |||
TMPY-01938 |
CD98 Protein, Human, Recombinant (His)
4T2HC,4F2,CD98HC,NACAE,MDU1,4F2HC,CD98,solute carrier family... |
Human | HEK293 Cells |
CD98 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P08195-1. | |||
TMPY-05099 |
GBA/glucocerebrosidase Protein, Human, Recombinant (His)
glucosidase, β, acid,GLUC,GCB,GBA1,glucosidase, bet... |
Human | HEK293 Cells |
Mutations in the GBA gene, encoding the lysosomal hydrolase glucocerebrosidase (GCase), are the most common known genetic risk factor for Parkinson's disease (PD) and dementia with Lewy bodies (DLB). ASAH1 (acid ceramidase 1) and GBA2 (glucocerebrosidase 2) enzymes that mediate glucosylsphingosine production and metabolism are attractive therapeutic targets for treating mutant GBA-associated PD. | |||
TMPH-03291 |
FABP3 Protein, Rat, Recombinant (His & Myc)
Fabp3,Fatty acid-binding protein 3,Heart-type fatty... |
Rat | HEK293 Cells |
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. | |||
TMPY-02358 |
CD98 Protein, Mouse, Recombinant (His)
NACAE,AI314110,Ly-m10,Cd98,Mgp-2hc,4F2HC,Ly10,4F2,solute car... |
Mouse | HEK293 Cells |
CD98 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P10852-2. | |||
TMPY-06686 |
FASN Protein, Mouse, Recombinant (His)
fatty acid synthase,FAS,A630082H08Rik |
Mouse | E. coli |
FASN Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.23 kDa and the accession number is P19096. | |||
TMPJ-01073 |
FABP5 Protein, Human, Recombinant (His)
Fatty Acid-Binding Protein Epidermal,PA-FABP,FABP5,... |
Human | E. coli |
Fatty acid-binding protein 5 (FABP5) is a cytoplasm protein that belongs to the fatty-acid binding protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids. FABP5 can be expressed in keratinocytes, and is highly expressed in psoriatic skin. FABP5 has been shown to be involved in keratinocyte differentiation. FABP5 has high specificity for fatty acids, the highest affinity for C18 chain... | |||
TMPJ-00520 |
NANS Protein, Human, Recombinant (His)
N-Acetylneuraminic Acid Synthase,N-Acetylneuraminic... |
Human | E. coli |
Sialic Acid Synthase (NANS) is an enzyme that contains one AFP-like domain. NANS is ubiquitous and plays a role in the biosynthetic pathways of sialic acids. NANS produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN). It also can use N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively. | |||
TMPH-00889 |
FADS2 Protein, Human, Recombinant (His & SUMO)
Delta(6) fatty acid desaturase,FADS2,Fatty acid... |
Human | E. coli |
FADS2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.9 kDa and the accession number is O95864. | |||
TMPJ-00785 |
FABP3 Protein, Human, Recombinant (His)
H-FABP,FABP11,Fatty Acid-Binding Protein Heart,MDGI... |
Human | E. coli |
Fatty Acid Binding Protein 3 (FABP3) is a small cytoplasmic protein (15 kDa) that is released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, FABP3 is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-types. They form 14-15 kDa proteins and are thought to p... | |||
TMPJ-00908 |
LMW-PTP Protein, Human, Recombinant (His)
Low Molecular Weight Cytosolic Acid Phosphatase,Adi... |
Human | E. coli |
Low Molecular Weight Phosphotyrosine Protein Phosphatase (LMW-PTP) is a member of the low molecular weight phosphotyrosine protein phosphatase family. LMW-PTP serves as an acid phosphatase and a protein tyrosine phosphatase (PTPase) by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. LMW-PTP can be detected in all human tissues, including adipocytes. LMW-PTP is a cytosolic enzyme that regulate cell proliferation and growth of leiomyomas during dephosphorylation of t... | |||
TMPH-03181 |
LaaA Protein, Pseudomonas azotoformans, Recombinant (His & Myc & SUMO)
L-amino acid amidase,laaA |
Pseudomonas azotoformans | E. coli |
Hydrolyzes L-prolinamide, L-proline-p-nitroanilide, L-alaninamide, L-methioninamide, piperidine-2-carboxamide and piperazine-2-carboxamide. Has a much lower activity towards piperazine-2-tert-butylcarboxamide. Does not hydrolyze dipeptides and D-prolinamide. LaaA Protein, Pseudomonas azotoformans, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 54.5 kDa and the accession number is Q76KX0. | |||
TMPY-00960 |
ACP5 Protein, Human, Recombinant (His)
acid phosphatase 5, tartrate resistant,TRAP,SPENCDI |
Human | HEK293 Cells |
ACP5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35 kDa and the accession number is A0A024R7F8. | |||
TMPJ-00853 |
DAO Protein, Human, Recombinant (His)
D-Amino-Acid Oxidase,DAMOX,DAAO,DAO |
Human | E. coli |
D-Amino-Acid Oxidase (DAO) belongs to the DAMOX/DASOX family. DAO is a peroxisomal enzyme which founctions as a homodimer to oxidizes D-amino acids to the corresponding imino acids, producing ammonia and hydrogen peroxide. D-amino-acid oxidase regulates the level of the neuromodulator D-serine in the brain, has a high activity towards D-DOPA and contributes to dopamine synthesis. D-amino-acid oxidase could act as a detoxifying agent which removes D-amino acids accumulated during aging. It also a... | |||
TMPY-01414 |
ACP5 Protein, Mouse, Recombinant (His)
TRAP,acid phosphatase 5, tartrate resistant,TRACP |
Mouse | HEK293 Cells |
ACP5 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.8 kDa and the accession number is Q05117. | |||
TMPJ-00869 |
GLB1 Protein, Human, Recombinant (His)
Lactase,Acid Beta-Galactosidase,Elastin Receptor 1,... |
Human | HEK293 Cells |
β Galactosidase is a lysosomal β Galactosidase that hydrolyzes the terminal β Galactose from Ganglioside and Keratan sulfate. In lysosome, the mature β Galactosidase protein associates with Cathepsin A and Neuraminidase 1 to form the lysosomal multienzyme complex . An alternative splicing at the RNA level of β Galactosidase results a catalytically inactive β Galactosidase that plays an important role in vascular development. Defects of β-galactosidase (GLB1) are the cause of diseases like GM1-ga... | |||
TMPY-06683 |
FASN Protein, Human, Recombinant (His)
OA-519,fatty acid synthase,FAS,SDR27X1 |
Human | E. coli |
FASN Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 35.26 kDa and the accession number is P49327. | |||
TMPY-05678 |
Siglec-15 Protein, Cynomolgus, Recombinant (hFc)
sialic acid binding Ig-like lectin 15 |
Cynomolgus | HEK293 Cells |
Siglec-15 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53 kDa and the accession number is A0A2K5UY47. | |||
TMPY-00190 |
ULBP-6 Protein, Human, Recombinant (hFc)
retinoic acid early transcript 1L,RAET1L,ULBP6 |
Human | HEK293 Cells |
ULBP6/RAET1L, is a polymorphic locus that expresses a functional transcript. ULBP6 had a more restricted expression profile in cell lines and primary human tissues than other NKG2D ligands, but expression was detected in several human papillomavirus-positive cervical carcinoma cell lines and was inducible on infection with human CMV. Expression of ULBP6 on target cells induced a significant increase in NK-cell killing. ULBP-6 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cel... | |||
TMPH-03237 |
Orm1 Protein, Rat, Recombinant (His)
Alpha-1-acid glycoprotein,Orosomucoid,Orm1 |
Rat | E. coli |
Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Appears to function in modulating the activity of the immune system during the acute-phase reaction. Orm1 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.7 kDa and the accession number is P02764. | |||
TMPY-02472 |
DOPA Decarboxylase/DDC Protein, Mouse, Recombinant (His)
Aadc,dopa decarboxylase (aromatic L-amino acid deca... |
Mouse | Baculovirus Insect Cells |
DOPA Decarboxylase/DDC Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 55.2 kDa and the accession number is O88533. | |||
TMPY-01060 |
DOPA Decarboxylase/DDC Protein, Human, Recombinant (His)
dopa decarboxylase (aromatic L-amino acid decarboxy... |
Human | Baculovirus Insect Cells |
DOPA Decarboxylase/DDC Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 55 kDa and the accession number is Q53Y41. | |||
TMPY-00575 |
ULBP-6 Protein, Human, Recombinant (His)
RAET1L,retinoic acid early transcript 1L,ULBP6 |
Human | HEK293 Cells |
ULBP6/RAET1L, is a polymorphic locus that expresses a functional transcript. ULBP6 had a more restricted expression profile in cell lines and primary human tissues than other NKG2D ligands, but expression was detected in several human papillomavirus-positive cervical carcinoma cell lines and was inducible on infection with human CMV. Expression of ULBP6 on target cells induced a significant increase in NK-cell killing. ULBP-6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cel... | |||
TMPH-02811 |
NRK1 Protein, Mouse, Recombinant (His)
Ribosylnicotinamide kinase 1,Nmrk1,Ribosylnicotinic acid... |
Mouse | E. coli |
Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). | |||
TMPH-00880 |
ASAH1 Protein, Human, Recombinant (His & SUMO)
AC,Acid CDase,HSD33,Acylsphingosine deacylase,N-acy... |
Human | E. coli |
ASAH1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 58.7 kDa and the accession number is Q13510. | |||
TMPH-00176 |
PucL Protein, Bacillus subtilis, Recombinant (His & Myc)
Uric acid degradation bifunctional protein PucL,puc... |
Bacillus subtilis | E. coli |
Catalyzes two steps in the degradation of uric acid, i.e. the oxidation of uric acid to 5-hydroxyisourate (HIU) and the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin. PucL Protein, Bacillus subtilis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 64.0 kDa and the accession number is O32141. | |||
TMPY-03278 |
SMPDL3A Protein, Human, Recombinant (His)
yR36GH4.1,sphingomyelin phosphodiesterase, acid-lik... |
Human | HEK293 Cells |
SMPDL3A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.3 kDa and the accession number is Q92484. | |||
TMPH-00433 |
Ex-FABP Protein, Coturnix coturnix japonica, Recombinant (His & Myc)
Extracellular fatty acid-binding protein,Lipocalin ... |
Coturnix coturnix japonica | E. coli |
Siderocalin-like lipocalin tightly binding a variety of bacterial ferric siderophores, also binds long-chain unsaturated fatty acids such as linoleic acid, oleic acid, arachidonic acid and, with a lower affinity, long chain saturated fatty acids such as steraic acid. May act as an antibacterial factor, through dual ligand specificity, both as a siderophore-sequestrating molecule and a lysophosphatidic acid (LPA) sensor. Ex-FABP Protein, Coturnix coturnix japonica, Recombinant (His & Myc) is expr... | |||
TMPH-03434 |
BIO3 Protein, S. cerevisiae, Recombinant (His & Myc)
Diaminopelargonic acid synthase,BIO3,7,8-diamino-pe... |
Saccharomyces cerevisiae | E. coli |
Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor. BIO3 Protein, S. cerevisiae, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 58.7 kDa and the accession number is P50277. | |||
TMPH-01510 |
HAO2 Protein, Human, Recombinant (His & SUMO)
Long-chain L-2-hydroxy acid oxidase,Long chain alph... |
Human | E. coli |
Catalyzes the oxidation of L-alpha-hydroxy acids as well as, more slowly, that of L-alpha-amino acids. | |||
TMPH-02490 |
ASAH1 Protein, Mouse, Recombinant (GST & His & Myc)
Acid CDase,HSD-33,Acid ceramidase,N-acylsp... |
Mouse | E. coli |
ASAH1 Protein, Mouse, Recombinant (GST & His & Myc) is expressed in E. coli expression system with N-10XHis-GST and C-Myc tag. The predicted molecular weight is 43.8 kDa and the accession number is Q9WV54. | |||
TMPJ-00671 |
FABP7 Protein, Human, Recombinant (His)
Fatty Acid-Binding Protein 7,Mammary-Derived Growth... |
Human | E. coli |
Fatty Acid-Binding Protein 7 (FABP7) is a cytoplasm protein that belongs to the Fatty-acid Binding Protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids. FABP7 is predominately expressed in brain and neural tissues. FABP7 is involved in fatty acid uptake and intracellular transport and is important in brain development. FABP7 plays a critical role in the transport of a so far unknow... | |||
TMPY-01878 |
L-FABP Protein, Human, Recombinant (His)
fatty acid binding protein 1, liver,FABPL,L-FABP |
Human | E. coli |
Fatty acid-binding protein, liver, also known as Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, FABP1 and FABPL,is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP1 and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is t... | |||
TMPJ-00426 |
Siglec-5 Protein, Cynomolgus, Recombinant (His)
Sialic acid-binding Ig-like lectin 5,Siglec-5 |
Cynomolgus | HEK293 Cells |
Sialic acid-binding Ig-like lectin 5 is a protein that in Cynomolgus is encoded by the SIGLEC5 gene, Cynomolgus SIGLEC5 cDNA encodes 551 amino acids (aa) that include a 16 aa signal sequence, a 439aa extracellular domain (ECD) with three Ig-like domains, a transmembrane region and a cytoplasma tail. No Siglec has been shown to recognized any cell surface ligand other than sialic acids, suggesting that interactions with glycans containing this carbohydrate are important in mediating the biologic... | |||
TMPH-03276 |
DAO Protein, Rat, Recombinant (His & Myc)
D-amino-acid oxidase,Dao1,DAMOX,DAO,DAAO |
Rat | E. coli |
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. DAO Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression sy... | |||
TMPH-00378 |
Midkine Protein, Chicken, Recombinant (His & Myc)
Midkine,RIHB,Retinoic acid-induced heparin-binding ... |
Chicken | E. coli |
Has mitogenic activity, and neurite extension activity for PC12 cells. Midkine Protein, Chicken, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 20.9 kDa and the accession number is P24052. | |||
TMPY-01549 |
CRABP2 Protein, Human, Recombinant (His)
RBP6,cellular retinoic acid binding protein 2,CRABP... |
Human | E. coli |
CRABP2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 16.5 kDa and the accession number is P29373. | |||
TMPH-02621 |
DAO Protein, Mouse, Recombinant (His)
DAMOX,Dao1,DAO,DAAO,D-amino-acid oxidase |
Mouse | E. coli |
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. DAO Protein, Mouse, Recombinant (His) is expressed in E. coli expression system... | |||
TMPY-02051 |
FABP2 Protein, Human, Recombinant (His)
MGC133132,fatty acid binding protein 2,FABPI,I-FABP |
Human | E. coli |
Fatty acid binding protein (FABP) is one of the intracellular proteins, with a low molecular weight of approximately 15 kDa, that plays important roles in the transportation and metabolism of long-chain fatty acids. FABP family proteins could be used as tissue specific injury marker based on the following characteristics of FABP. The intestinal fatty acid binding protein (I-FABP), or fatty acid-binding protein 2 (FABP2), an intracellular protein expressed only in the intestine, involved in the a... | |||
TMPY-04623 |
PRRG2 Protein, Human, Recombinant (mFc)
PRGP2,proline rich Gla (G-carboxyglutamic acid) 2,P... |
Human | HEK293 Cells |
The genes encoding a family of proteins termed proline-rich gamma-carboxyglutamic acid (PRRG) proteins were identified and characterized more than a decade ago. These novel membrane proteins have an extracellular gamma-carboxyglutamic acid (Gla) protein domain and cytosolic WW binding motifs. Several of the PRRG-interacting proteins are essential for a variety of physiologic processes. | |||
TMPY-02952 |
SIAE Protein, Human, Recombinant (His)
CSE-C,AIS6,CSEC,LSE,YSG2,sialic acid acetylesterase |
Human | Baculovirus Insect Cells |
Sialate O-acetylesterase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. It is widely expressed with high expression in the testis, prostate, and colon. The systematic name of this enzyme class is N-acyl-O-acetylneuraminate O-acetylhydrolase. Other names in common use include N-acetylneuraminate acetyltransferase, sialate 9(4)-O-acetylesterase, and sialidase. Sialate O-acetylesterase catalyzes the removal of O-acetyl ester groups from position 9 of the p... | |||
TMPY-02189 |
CRABP2 Protein, Mouse, Recombinant (His)
Crabp-2,cellular retinoic acid binding protein 2,AI... |
Mouse | E. coli |
CRABP2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 17.1 kDa and the accession number is P22935. | |||
TMPY-04143 |
Chemerin/RARRES2 Protein, Mouse, Recombinant (hFc)
0610007L05Rik,retinoic acid receptor responder (taz... |
Mouse | HEK293 Cells |
Chemerin/RARRES2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.6 kDa and the accession number is Q9DD06. | |||
TMPH-00713 |
Polyphosphate kinase Protein, E. coli, Recombinant (His & Myc)
Polyphosphoric acid kinase,ATP-polyphosphate phosph... |
E. coli | E. coli |
Polyphosphate kinase Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 87.7 kDa and the accession number is P0A7B1. | |||
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Cat. No. | Product Name | Target | Signaling Pathways |
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T39424 |
Cyanuric acid-13C3
Cyanuric acid-13C3 |
||
Cyanuric acid-13C3 是 13C 标记的 Cyanuric acid。 | |||
T38037 |
Caffeic Acid-13C3
Caffeic Acid-13C3 |
||
Caffeic acid-13C3 is an isotopically enriched form of caffeic acid that is intended for use as an internal standard for the quantification of caffeic acid by GC- or LC-MS. Caffeic acid is an inhibitor of 5-LO , with IC50 values of 3.7-72 μM, and 12-LO, with IC50 values of 5.1-30 μM. | |||
T40980 |
Palmitic acid-13C2
Palmitic acid-13C2 |
||
Palmitic acid-13C2 is the 13C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells. | |||
T40141 |
Palmitic acid-13C16 sodium
Palmitic acid-13C16 sodium |
||
Palmitic acid-13C16 sodium, a 13C-labeled form of the naturally occurring saturated fatty acid Palmitic acid sodium, is prevalent in animals and plants. This compound can trigger the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in mouse granulosa cells. | |||
T38638 |
4-Trifluoromethylsalicylic acid-13C6
4-Trifluoromethylsalicylic acid-13C6,Desacetyl triflusal-13C6 |
||
4-Trifluoromethylsalicylic acid-13C6 是 13C 标记的 4-Trifluoromethylsalicylic acid,主要用于药物开发过程中的定量示踪剂。4-Trifluoromethylsalicylic acid 也是一种血小板聚集抑制剂。 | |||
TMIH-0037 |
2-Methylpropanedioic acid-d3
methyl-d3-malonic acid |
||
2-Methylpropanedioic acid-d3 是 2-Methylpropanedioic acid 的氘代化合物。2-Methylpropanedioic acid 的 CAS 号为 516-05-2。Methylmalonic acid 是癌症患者缺乏维生素 B-12的指标。 | |||
T19311 |
Enzalutamide carboxylic acid D6
MDV3100 carboxylic acid D6 |
Others | Others |
Enzalutamide carboxylic acid is an inactive metabolite of Enzalutamide. Enzalutamide carboxylic acid D6 is the deuterium labeled Enzalutamide carboxylic acid (MDV3100 carboxylic acid). | |||
T41001 |
L-Lactic acid-13C3
L-Lactic acid-13C3,(S)-2-hydroxypropanoic-13-C3 |
||
L-Lactic acid-13C3 is a stable isotope labeled L-Lactic acid analog. L-Lactic acid-13C3 can be used for lactate metabolism research. | |||
T67921 |
Retinoic acid-d5
all-trans-Retinoic acid-d5,Isotretinoin-d5,Vitamin A acid-d5,Accutane-d5,ATRA-d5 |
Retinoid Receptor | Metabolism |
Retinoic acid-d5 (Vitamin A acid-d5)是视黄酸的氘标记形式。视黄酸是一种天然的RAR 核受体激动剂, 对 RARα/β/γ 的 IC50 为 14 nM,与 PPARβ/δ 结合的Kd 为 17 nM。视黄酸是维生素a 的代谢物,在细胞生长、分化和器官发育中起着重要作用。视黄酸通过激活视黄酸受体α作为转录因子Nrf2的抑制剂来发挥作用。 | |||
T35790 |
Palmitic acid-1,2,3,4-13C4
Palmitic Acid-13C (C1, C2, C3, and C4 labeled) |
||
Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellula... | |||
TMIH-0030 |
2,2,14,14-tetramethyl-8-oxopentadecanedioic acid-d4
Bempedoic Acid Impurity 1-d4 |
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2,2,14,14-tetramethyl-8-oxopentadecanedioic acid-d4 是 2,2,14,14-tetramethyl-8-oxopentadecanedioic acid 的氘代化合物。2,2,14,14-tetramethyl-8-oxopentadecanedioic acid 的 CAS 号为 413624-71-2。2,2,14,14-Tetramethyl-8-oxopentadecanedioic acid 属于酮类化合物,详细信息请参考专利文献 WO2002030860A2,化合物 II-9。它在心血管疾病、血脂异常、蛋白异常和糖代谢紊乱方面具有研究的价值。 | |||
T35695 |
Oleic Acid-13C
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Oleic acid-13C is intended for use as an internal standard for the quantification of oleic acid by GC- or LC-MS. Oleic acid is a monounsaturated fatty acid and a major component of membrane phospholipids that has been found in human plasma, cell membranes, and adipose tissue.1,2 It contributes approximately 17% of the total fatty acids esterified to phosphatidylcholine, the major phospholipid class in porcine platelets.1 Oleic acid inhibits collagen-stimulated platelet aggregation by approximate... | |||
T35698 |
Octanoic Acid-13C
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Octanoic acid-13C is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.1 Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).2 Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA d... | |||
T35697 |
Lauric Acid-13C
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Lauric acid-13C is intended for use as an internal standard for the quantification of lauric acid by GC- or LC-MS. Lauric acid is a medium-chain saturated fatty acid. It has been found at high levels in coconut oil.1Lauric acid induces the activation of NF-κB and the expression of COX-2, inducible nitric oxide synthase (iNOS), and IL-1α in RAW 264.7 cells when used at a concentration of 25 μM.2 | |||
T40915 |
L-Aspartic acid 13C
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L-Aspartic acid 13C is a 13C labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable prodrug for colon-specific drug deliverly. | |||
T35791 |
Palmitic acid-13C
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Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid-13C contains 13C at the C2 position and has been used in the study of free fatty acid incorporation into phospholipid fatty acids in soil microbes.1 Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.2 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.3 Palmitic ... | |||
T12445 |
Phenolic acid
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Others | Others |
Phenolic acid is an endogenous metabolite. | |||
T39565 |
L-Glutamic acid-15N
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L-Glutamic acid-15N is the 15N-labeled version of L-Glutamic acid, an excitatory neurotransmitter and an agonist at metabotropic, kainate, NMDA, and AMPA glutamate receptor subtypes. It directly activates the release of dopamine (DA) from dopaminergic terminals. | |||
T19491 |
O-Desmethyl Mebeverine acid-d5
O-Desmethyl Mebeverine acid D5,去甲基美贝维林酸 D5 |
Others | Others |
O-desmethyl Mebeverine acid D5 is the deuterium labeled O-desmethyl Mebeverine acid. | |||
T39423 |
Palmitic acid-13C sodium
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Sodium palmitate-13C is the 13C-labeled variant of palmitic acid, a long-chain saturated fatty acid prevalent in animals and plants. This compound has been shown to induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer-binding protein homologous protein (CHOP) in mouse granulosa cells. | |||
T19490 |
O-desmethyl Mebeverine acid D5 hydrochloride
O-desmethyl Mebeverine acid D5 hydrochloride (1329488-46-1 free base) |
Others | Others |
O-desmethyl Mebeverine acid D5 hydrochloride is the deuterium labeled O-desmethyl Mebeverine acid. | |||
T35789 |
Palmitic acid-1-13C
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Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.1 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.2 Palmitic acid is involved in the acylation of proteins to anchor membrane-bound proteins to the lipid bilayer.2,3,4,5,6 |1. Santos, M.J., López-Jurado, M., Llopis, J., et a... | |||
T13155 |
Tiaprofenic acid D3
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Others | Others |
Tiaprofenic acid D3 is a deuterium-labeled Tiaprofenic acid. Tiaprofenic acid is a nonsteroidal anti-inflammatory drug and treatment of rheumatic diseases. | |||
T11240 |
Ethacrynic acid D5
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Others | Others |
Ethacrynic acid, a diuretic, functions as an inhibitor of L-type voltage-dependent and store-operated calcium channels, facilitating the relaxation of airway smooth muscle (ASM) cells. It exhibits anti-inflammatory effects, notably reducing retinoid-induced ear edema in mice, and inhibits glutathione S-transferases (GSTs), making it a potent suppressor of the NF-kB signaling pathway. Additionally, ethacrynic acid modulates leukotriene formation. A variant, Ethacrynic acid D5, is distinguished by... | |||
T71305 |
Clofibric Acid-d4
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Clofibric acid-d4 is intended for use as an internal standard for the quantification of clofibric acid by GC- or LC-MS. Clofibric acid is a peroxisome proliferator-activated receptor α (PPARα) agonist (EC50 = 50 µM in a transactivation assay) and the active metabolite of clofibrate. It is formed from clofibrate by tissue and serum esterases. Dietary administration of clofibric acid (0.067-0.22%) reduces serum cholesterol, phospholipid, and triglyceride levels in rats. It decreases glutamate oxal... | |||
T71303 |
Flufenamic Acid-d4
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Flufenamic acid-d4 is intended for use as an internal standard for the quantification of flufenamic acid by GC- or LC-MS. Flufenamic acid is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 3 and 9.3 µM for human COX-1 and COX-2, respectively). Flufenamic acid inhibits TNF-α-induced increases in COX-2 levels and NF-κB activation in HT-29 colon cancer cells in a concentration-dependent manner. It inhibits calcium influx induced by fMLP or A23187 in human polymorphonuclear... | |||
T40376 |
L-Phenylalanine-15N
L-苯丙氨酸 15N,(S)-2-Amino-3-phenylpropionic acid-15N,L-Phenylalanine-15N |
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
L-Phenylalanine-15N ((S)-2-Amino-3-phenylpropionic acid-15N) 是 15N 标记的 L-Phenylalanine。L-Phenylalanine 是从大肠杆菌中分离出来的一种必需氨基酸。 L-Phenylalanine 广泛用于食品香精和药物的生产。 | |||
T12135 |
Mycophenolic acid-d3
Mycophenolate-d3,Mycophenolate D3 |
Others; Antibacterial | Microbiology/Virology; Others |
Mycophenolic acid-d3 (Mycophenolate-d3) 是 Mycophenolic acid 的衍生物。Mycophenolic acid 是一种降低GTP 水平和损害RNA 聚合酶II (RNAP II)转录延伸的化合物,促进了近端位点的使用,能够逆转虫草素对选择性聚腺苷化的作用。 | |||
T11869 |
Losartan (D4 Carboxylic Acid)
E-3174 D4,氯沙坦羧酸 D4,EXP-3174 D4 |
Others | Others |
Losartan D4 Carboxylic Acid is the deuterium labeled Losartan, which is an angiotensin II receptor antagonist. | |||
T69462 |
Deulinoleic acid
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Deulinoleic acid is a lipid peroxidation inhibitor and antioxidant. | |||
TMIJ-0224 |
Fenofibrate EP Impurity B-d6
Fenofibric Acid-d6 |
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Fenofibrate EP Impurity B-d6 是 Fenofibrate EP Impurity B 的氘代化合物。Fenofibrate EP Impurity B 的 CAS 号为 42017-89-0。Fenofibric acid 是 fenofibrate 的活性代谢物,是PPAR激动剂,对 PPARα、PPARγ 和 PPARδ 的EC50值分别为 22.4、1.47 和 1.06 µM。它抑制COX-2的活性,IC50值为 48 nM。 | |||
TMIH-0261 |
Homovanillic acid-d3
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Homovanillic acid-d3 是 Homovanillic acid 的氘代化合物。 | |||
TMIH-0254 |
Glycochenodeoxycholic Acid-d4
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Glycochenodeoxycholic Acid-d4 是 Glycochenodeoxycholic Acid 的氘代化合物。 | |||
TMIH-0411 |
Oseltamivir-d3 acid
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Oseltamivir-d3 acid 是 Oseltamivir acid 的氘代化合物。Oseltamivir acid 的 CAS 号为 196618-13-0。 | |||
TMIH-0262 |
Homovanillic acid-d5
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Homovanillic acid-d5 是 Homovanillic acid 的氘代化合物。 | |||
TMIH-0145 |
Chenodeoxycholic Acid-d4
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Chenodeoxycholic Acid-d4 是 Chenodeoxycholic Acid 的氘代化合物。 | |||
TMIH-0148 |
Cholic acid-d4
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Cholic acid-d4 是 Cholic acid 的氘代化合物。 | |||
TMIH-0243 |
Folic Acid-d4
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Folic Acid-d4 是 Folic Acid 的氘代化合物。 | |||
TMIH-0566 |
Tetradecanedioic acid-d4
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Tetradecanedioic acid-d4 是 Tetradecanedioic acid 的氘代化合物。Tetradecanedioic acid 的 CAS 号为 821-38-5。Tetradecanedioic acid 是内源性代谢物的一种,是一种长链脂肪酸类有机化合物。它能够作为有机阴离子转运多肽介导的药物-药物相互作用的候选生物标志物。 | |||
TMIH-0325 |
MefenaMic Acid-d4
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MefenaMic Acid-d4 是 MefenaMic Acid 的氘代化合物。MefenaMic Acid 的 CAS 号为 61-68-7。Mefenamic acid 是一种非甾体抗炎剂,可竞争性抑制hCOX-1和hCOX-2,IC50值分别为 40 nM 和 3 μM。 | |||
TMIH-0109 |
Bempedoic acid-d4
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Bempedoic acid-d4 是 Bempedoic acid 的氘代化合物。Bempedoic acid 的 CAS 号为 738606-46-7。ETC-1002 是一种 ATP-柠檬酸裂解酶抑制剂,可激活AMPK。它是脂质和碳水化合物代谢的调节剂。 | |||
T64570 |
Succinic acid-d6
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Succinic acid-d6 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64570。 | |||
TMIH-0513 |
Salicylic Acid-d4
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Salicylic Acid-d4 是 Salicylic Acid 的氘代化合物。 | |||
TMIH-0322 |
Mebeverine Acid-d5
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Mebeverine Acid-d5 是 Mebeverine Acid 的氘代化合物。Mebeverine Acid 的 CAS 号为 475203-77-1。Mebeverine acid 是美贝维林的次级代谢产物,可用作口服美贝维林的标志物。 | |||
TMID-0097 |
Ethyl-d5-malonic Acid
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Ethyl-d5-malonic Acid 是 Ethyl-malonic Acid 的氘代化合物。Ethyl-malonic Acid 的 CAS 号为 601-75-2。Ethylmalonic acid 是潜在有毒物质,非致癌性,与神经性厌食和甲氧基脱羧酶缺乏症有关。 | |||
TMIH-0286 |
Isochenodeoxycholic Acid-d4
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Isochenodeoxycholic Acid-d4 是 Isochenodeoxycholic Acid 的氘代化合物。Isochenodeoxycholic Acid 的 CAS 号为 566-24-5。 | |||
TMIH-0432 |
Phenylboronic acid-d5
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Phenylboronic acid-d5 是 Phenylboronic acid 的氘代化合物。 | |||
TMIH-0590 |
Ursodeoxycholic Acid-d4
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Ursodeoxycholic Acid-d4 是 Ursodeoxycholic Acid 的氘代化合物。 | |||
TMIH-0257 |
Glycoursodeoxycholic Acid-d4
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Glycoursodeoxycholic Acid-d4 是 Glycoursodeoxycholic Acid 的氘代化合物。Glycoursodeoxycholic Acid 的 CAS 号为 64480-66-6。Glycoursodeoxycholic acid 是一种酰基甘氨酸和胆汁酸-甘氨酸缀合物,是熊去氧胆酸的代谢物。 | |||
TMIH-0218 |
Enzalutamide-d6 Carboxylic Acid
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Enzalutamide-d6 Carboxylic Acid 是 Enzalutamide Carboxylic Acid 的氘代化合物。Enzalutamide Carboxylic Acid 的 CAS 号为 1242137-15-0。Enzalutamide carboxylic acid 是 Enzalutamide 非活性代谢物。Enzalutamide 是雄激素受体 (AR) 拮抗剂。 | |||
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