MMPI-1154

Name: MMPI-1154
Brand: TargetMol
SKU: T38800
Rating: 4.5 (1 reviews)

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产品编号 T38800Cas号 1382722-47-5

MMPI-1154 is a highly promising imidazole-carboxylic acid (ICA) MMP-2 inhibitor (IC 50 = 6.6 μM) with excellent cardio-cytoprotective properties. It is specifically designed for the study of acute myocardial infarction. Additionally, MMPI-1154 exhibits significant inhibitory effects on MMP-13, MMP-1, and MMP-9 activities with IC 50 values of 1.8 μM, 10 μM, and 13 μM, respectively.

MMPI-1154

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产品编号 T38800Cas号 1382722-47-5

规格	价格	库存	数量
2 mg	¥ 2,130	5日内发货

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产品描述	MMPI-1154 is a highly promising imidazole-carboxylic acid (ICA) MMP-2 inhibitor (IC 50 = 6.6 μM) with excellent cardio-cytoprotective properties. It is specifically designed for the study of acute myocardial infarction. Additionally, MMPI-1154 exhibits significant inhibitory effects on MMP-13, MMP-1, and MMP-9 activities with IC 50 values of 1.8 μM, 10 μM, and 13 μM, respectively.
靶点活性	MMP9:13 μM (IC50), MMP13:1.8 μM (IC50), MMP2:6.6 μM (IC50), MMP1:10 μM (IC50)
体外活性	MMPI-1154 (1-100 μM) inhibits MMP-2 enzyme isolated from rat heart?in vitro, and 100% inhibition appears at the concentraction 100 μM[1].MMPI-1154 (1 μM) shows significant cardio-cytoprotecion, significantly decreases infarct size in an ex vivo model for acute myocardial infarction[1].