L-Triguluronic acid, a linear polysaccharide copolymer consisting of three L-guluronic acid (G) units, serves as a precursor for Alginate[1]. Alginate, an unbranched polyanionic polysaccharide, has applications in the development of delivery carriers for anti-fungal agents[2].

Alginate is a generic name assigned to a series of polyanionic polysaccharides of β-d-mannuronic acid (M) and α-l-guluronic acid (G). Alginate is linked by a 1→4 linkage and displaying chain homosequences of MMM and GGG, interdispersed with MGM heterosequences[1].Alginate is widely used for obtainment of drug delivery systems due to its non-toxicity, biodegradability, biocompatibility, mucoadhesive, and non-immunogenic properties. Additionally, alginate-based antifungal delivery systems have great potential in the treatment of fungal infections in vivo[1].