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CBK289001 is a tartrate-resistant acid phosphatase (TRAP/ACP5) inhibitor. CBK289001 inhibits TRAP 5b MV , TRAP 5b OX and TRAP 5a OX with IC 50 s of 125 μM, 4.21 μM and 14.2 μM, respectively.
CBK289001 is a tartrate-resistant acid phosphatase (TRAP/ACP5) inhibitor. CBK289001 inhibits TRAP 5b MV , TRAP 5b OX and TRAP 5a OX with IC 50 s of 125 μM, 4.21 μM and 14.2 μM, respectively.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | 询价 | 6-8周 |
产品描述 | CBK289001 is a tartrate-resistant acid phosphatase (TRAP/ACP5) inhibitor. CBK289001 inhibits TRAP 5b MV , TRAP 5b OX and TRAP 5a OX with IC 50 s of 125 μM, 4.21 μM and 14.2 μM, respectively. |
体外活性 | Only CBK289001 inhibits TRAP3 high cell migration in a concentration-dependent manner. Significant inhibition of migration appeared from 24 h after treatment and reduced migration velocity over 30 hours is reached with concentrations of either 20 μM or 100 μM[1]. CBK289001 inhibits TRAP-dependent migration when treating TRAP-overexpressing MDA-MB-231 breast cancer cells[1]. |
分子量 | 396.4 |
分子式 | C19H20N6O4 |
CAS No. | 1212663-24-5 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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