Poacic Acid is a plant-derived stilbenoid exhibiting antifungal activity by localizing to the yeast cell wall and disrupting the production and assembly of β-1,3-glucan in fungal cell walls. It shows fungicidal activity against Saccharomyces cerevisiae and plasma membrane-compromised Candida albicans mutants [1].

Poacic Acid 在多种实验条件下对酵母细胞展现了不同的作用机制。在(0-512 μg/ml; 48 h)浓度在或超过256 μg/mL时，对Saccharomyces cerevisiae有显著的生长抑制效果。同时，对Candida albicans中缺失ERG11和ERG3基因的突变株表现出杀菌活性[1]。在(1 mM; 1-42 h)的条件下，Poacic Acid能增加Saccharomyces cerevisiae细胞壁的几丁质含量，并调整其在细胞壁中的分布[1]。而在(512 μg/mL; 36 h)的条件及添加额外的β-葡聚糖、几丁质或金属离子时，该化合物对Saccharomyces cerevisiae的抑制作用有所减弱[1]。