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17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α
还可以产品编号 T37948Cas号 294856-01-2
别名 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α
A number of 17-phenyl trinor prostaglandin F2α(17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma.1,2,3Of these, the ones wherein the 13,14-double bond has been hydrogenated retain relatively good potency, but show a significantly reduced incidence of local irritant side effects.417-trifluoromethylphenyl-13,14-dihydro trinor PGF2αbears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl-13,14-dihydro trinor PGF2αwould act very much like the free acid of latanoprost.
17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α
还可以产品编号 T37948 别名 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2αCas号 294856-01-2
A number of 17-phenyl trinor prostaglandin F2α(17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma.1,2,3Of these, the ones wherein the 13,14-double bond has been hydrogenated retain relatively good potency, but show a significantly reduced incidence of local irritant side effects.417-trifluoromethylphenyl-13,14-dihydro trinor PGF2αbears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl-13,14-dihydro trinor PGF2αwould act very much like the free acid of latanoprost.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 1 mg | ¥ 1,220 | 35日内发货 | |
| 5 mg | ¥ 5,390 | 35日内发货 | |
| 10 mg | ¥ 9,530 | 35日内发货 |
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| 产品描述 | A number of 17-phenyl trinor prostaglandin F2α(17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma.1,2,3Of these, the ones wherein the 13,14-double bond has been hydrogenated retain relatively good potency, but show a significantly reduced incidence of local irritant side effects.417-trifluoromethylphenyl-13,14-dihydro trinor PGF2αbears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl-13,14-dihydro trinor PGF2αwould act very much like the free acid of latanoprost. |
| 别名 | 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α |
| 分子量 | 458.518 |
| 分子式 | C24H33F3O5 |
| CAS No. | 294856-01-2 |
| 密度 | no data available |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度信息 | DMF: 30 mg/mL Ethanol: 50 mg/mL PBS (pH 7.2): 1 mg/mL DMSO: 25 mg/mL |
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