Myhc-α(334–352) is a sequence fragment comprised of amino acid residues 334 to 352 of the myocardial myosin heavy chain α (MYHC-α). It serves as an immunodominant epitope capable of inducing an autoimmune response in A/J mice, which leads to the development of myocarditis. Myhc-α(334–352) is utilized in research on the autoimmune pathways involved in myocarditis and dilated cardiomyopathy.