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MeAIB 是一种n -乙酰转移酶抑制剂,抑制SNAT2相关信号通路。MeAIB 是氨基酸转运系统a (ATA1)的特异性底物。氨基酸转运系统a (ATA1)以Na+流动调控短链中性氨基酸的摄取。
MeAIB 是一种n -乙酰转移酶抑制剂,抑制SNAT2相关信号通路。MeAIB 是氨基酸转运系统a (ATA1)的特异性底物。氨基酸转运系统a (ATA1)以Na+流动调控短链中性氨基酸的摄取。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 mg | ¥ 155 | 现货 |
产品描述 | MeAIB is an N-acetyltransferase inhibitor that inhibits SNAT2-related signaling pathways. MeAIB is a specific substrate for amino acid transport system a (ATA1). Amino acid transport system a (ATA1) regulates the uptake of short chain neutral amino acids by Na+ flow. |
体外活性 | ATA3是一种新型的氨基酸转运系统A的亚型,主要表达在肝脏和骨骼肌中。ATA1(亦称为GlnT)和ATA2(亦称为SAT2)已从大鼠和人体组织中克隆出来。这些转运蛋白以Na+依赖的方式控制着短链中性氨基酸的摄入[1]。 |
别名 | α-(Methylamino)isobutyric acid |
分子量 | 117.15 |
分子式 | C5H11NO2 |
CAS No. | 2566-34-9 |
Smiles | CNC(C)(C)C(O)=O |
密度 | 1.2000 g/cm3 (Estimated) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 45.0 mg/mL (384.1 mM), when pH is adjusted to 2 with 1M HCl. Sonication and heating to 60℃ are recommended. H2O: 90.0 mg/mL (768.2 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO/H2O
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