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Sodium aristolate 1(Aristolochic acid sodium salt), 作为某些中草药的组成成分,是引起肾脏毒性的主要原因。该化合物作为前体活性分子,通过硝基还原为胺的方式进行活化,进而形成具有细胞毒性的DNA加合物。
Sodium aristolate 1(Aristolochic acid sodium salt), 作为某些中草药的组成成分,是引起肾脏毒性的主要原因。该化合物作为前体活性分子,通过硝基还原为胺的方式进行活化,进而形成具有细胞毒性的DNA加合物。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 待询 | |
50 mg | 询价 | 待询 |
产品描述 | Sodium aristolate 1, also known as aristolochic acid sodium salt, is found in certain Chinese herbal medicines and causes nephrotoxicity. This proagent becomes active when its nitro groups are reduced to amines, which subsequently leads to the production of cytotoxic DNA adducts. |
别名 | 马兜铃酸I钠盐, TR 1736 sodium, Aristolochic acid I sodium |
分子量 | 363.25 |
分子式 | C17H10NNaO7 |
CAS No. | 10190-99-5 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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