Selcopintide acetate (Cpne7-DP), a synthetic peptide, mirrors the 344-353 amino acid sequence of the hCPNE7 protein. It effectively mimics CPNE7's in vitro activity, enhancing the expression of odontoblast markers like DSPP and Nestin. Selcopintide acetate has been shown to facilitate dentin regeneration across varying levels of dentinal defects, with the regenerated tissue exhibiting true dentin properties [1].

Selcopintide (Cpne7-DP) acetate 能直接渗透MDPC-23细胞；其在1和10 μg剂量下，剂量依赖性地提升dspp启动子活性。

Selcopintide (Cpne7-DP; 10 µg 在 0.5% 纤维蛋白凝胶中与人 DPC 细胞混合后皮下移植) 醋酸盐在浅腔和深腔模型中促进了牙本质样组织的形成以及管状牙本质和牙本质小管的再生，并导致牙本质小管闭塞[1]。