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Tetrahydrofolic acid (5,6,7,8-tetrahydrofolic acid) 是一种维生素 B9 衍生物,是生物体常见的一碳供体,参与生物体生长代谢。
Tetrahydrofolic acid (5,6,7,8-tetrahydrofolic acid) 是一种维生素 B9 衍生物,是生物体常见的一碳供体,参与生物体生长代谢。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
2 mg | ¥ 194 | 现货 | |
5 mg | ¥ 297 | 现货 | |
10 mg | ¥ 497 | 现货 |
产品描述 | Tetrahydrofolic acid (5,6,7,8-tetrahydrofolic acid) is a vitamin B9 derivative that is a common one-carbon donor in organisms and is involved in growth and metabolism. |
体外活性 | 在 Adh5-/- DT40 细胞中,Tetrahydrofolic acid(0-200 µM;3 天)导致细胞存活率迅速下降[1]。 |
体内活性 | 在 Adh5-/- 小鼠中,Tetrahydrofolic acid (62.5 mg/kg;腹腔注射;每日一次)造成了造血功能紊乱,增加了 Ser139-H2AX 的磷酸化,降低了祖细胞(HSPCs)的存活率[1]。 |
别名 | 四氢叶酸, th-folate, Tetrahydropteroylglutamic acid, folate-H4, 5,6,7,8-tetrahydrofolic acid |
分子量 | 445.43 |
分子式 | C19H23N7O6 |
CAS No. | 135-16-0 |
Smiles | Nc1nc2NCC(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)Nc2c(=O)[nH]1 |
密度 | 1.7g/cm3 |
存储 | store under nitrogen,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||
溶解度信息 | DMSO: 1 mg/mL (2.25 mM), Sonication is recommended. H2O: 1 mg/mL (2.25 mM), Sonication is recommended. | ||||||||||
溶液配制表 | |||||||||||
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