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Sulfadoxine (Sulphadoxine) 是磺胺类化合物,常与pyrimethamine 结合起到抗疟疾作用。它抑制HIV 在外周血单核细胞中的复制。
Sulfadoxine (Sulphadoxine) 是磺胺类化合物,常与pyrimethamine 结合起到抗疟疾作用。它抑制HIV 在外周血单核细胞中的复制。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
500 mg | ¥ 293 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 418 | 现货 |
产品描述 | Sulfadoxine (Sulphadoxine) is a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with bacteriostatic and antimalarial properties. |
激酶实验 | Competitive binding assays: Cells are harvested from 150-sq cm T-flasks, and cytosol is prepared at a protein concentration of approximately 2 mg/mL in phosphate buffer. Aliquots of this 180,000 ×g supernatant are then incubated with various concentrations of Tamoxifen and 2.5 nM [3H]estradiol for 16 hr at 0-4 ℃. The free steroids are absorbed by dextran-charcoal [l0 μL of 0.5% Dextran C-5% Norite A in TE buffer] for 1 hr at 0 ℃, and aliquots are counted after centrifugation at 800 ×g, 30 min. The relative binding ability of each competitor is taken as the ratio of the concentration of radioinert estradiol/competitor required to inhibit one-half of the specific [3H]estradiol binding, with the affinity of estradiol set at 100%. |
别名 | 周效磺胺, 磺胺多辛, Sulphadoxine |
分子量 | 310.33 |
分子式 | C12H14N4O4S |
CAS No. | 2447-57-6 |
Smiles | N(S(=O)(=O)C1=CC=C(N)C=C1)C=2C(OC)=C(OC)N=CN2 |
密度 | 1.441 g/cm3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 50 mg/mL (161.12 mM), Sonication is recommended. H2O: < 1 mg/mL (insoluble or slightly soluble) Ethanol: < 1 mg/mL (insoluble or slightly soluble) | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO
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