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MTOB (α-keto-γ-Methylthiobutyric acid) 是 c 末端结合蛋白 (CtBP) 的底物,可干扰 CtBP 在细胞培养物和小鼠中的致癌活性。它还积极调节 TCF-4 信号传导,导致癌症干细胞 (CSC) 生长和自我更新。
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MTOB (α-keto-γ-Methylthiobutyric acid) 是 c 末端结合蛋白 (CtBP) 的底物,可干扰 CtBP 在细胞培养物和小鼠中的致癌活性。它还积极调节 TCF-4 信号传导,导致癌症干细胞 (CSC) 生长和自我更新。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 513 | 现货 | |
5 mg | ¥ 1,750 | 现货 | |
10 mg | ¥ 2,720 | 现货 | |
25 mg | ¥ 4,450 | 现货 | |
50 mg | ¥ 6,270 | 现货 | |
100 mg | ¥ 8,450 | 现货 |
产品描述 | MTOB (α-keto-γ-Methylthiobutyric acid) is a substrate for c-terminal binding protein (CtBP) that interferes with the carcinogenic activity of CtBP in cell culture and mice. It also actively regulates TCF-4 signaling, leading to cancer stem cell (CSC) growth and self-renewal. |
别名 | α-keto-γ-Methylthiobutyric acid sodium salt, MTOB sodium salt, KMBA, 4-甲硫基-2-氧丁酸钠, 4-methylthio 2-oxobutyric acid sodium salt |
分子量 | 170.16 |
分子式 | C5H7NaO3S |
CAS No. | 51828-97-8 |
Smiles | [Na+].CSCCC(=O)C([O-])=O |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | PBS: 100 mg/mL (587.68 mM), Sonication is recommended. DMSO: 55 mg/mL (323.23 mM) | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO/PBS
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