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4-hydroperoxy 2-Nonenal

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产品编号 T36001Cas号 7439-43-2

4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids, such as linoleic acid and arachidonic acid, that is widely used as a marker of oxidative stress. 4-HNE exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. 4-hydroperoxy 2-Nonenal is the immediate precursor of 4-HNE formed from the cleavage of ω-6 hydroperoxides. Analogous reactions are expected to occur with hydroperoxides from other ω-6 fatty acids, particularly arachidonic acid.

4-hydroperoxy 2-Nonenal

4-hydroperoxy 2-Nonenal

Rating icon 还可以
产品编号 T36001Cas号 7439-43-2

4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids, such as linoleic acid and arachidonic acid, that is widely used as a marker of oxidative stress. 4-HNE exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. 4-hydroperoxy 2-Nonenal is the immediate precursor of 4-HNE formed from the cleavage of ω-6 hydroperoxides. Analogous reactions are expected to occur with hydroperoxides from other ω-6 fatty acids, particularly arachidonic acid.

规格价格库存数量
500 μg
询价
35日内发货
1 mg
询价
35日内发货
5 mg
询价
35日内发货
10 mg
询价
35日内发货
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产品介绍

生物活性
产品描述
4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids, such as linoleic acid and arachidonic acid, that is widely used as a marker of oxidative stress. 4-HNE exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. 4-hydroperoxy 2-Nonenal is the immediate precursor of 4-HNE formed from the cleavage of ω-6 hydroperoxides. Analogous reactions are expected to occur with hydroperoxides from other ω-6 fatty acids, particularly arachidonic acid.
化学信息
分子量172.224
分子式C9H16O3
CAS No.7439-43-2
密度0.999 g/cm3 (Predicted)
储存&溶解度
存储Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度信息
Ethanol:PBS (pH 7.2)(1:6): 0.5 mg/mL (2.9 mM), Sonication is recommended.
DMF: 30 mg/mL (174.19 mM), Sonication is recommended.
Ethanol: 30 mg/mL (174.19 mM), Sonication is recommended.
DMSO: 30 mg/mL (174.19 mM), Sonication is recommended.
溶液配制表
DMF/Ethanol/DMSO
1mg5mg10mg50mg
5 mM1.1613 mL5.8064 mL11.6128 mL58.0639 mL
10 mM0.5806 mL2.9032 mL5.8064 mL29.0320 mL
20 mM0.2903 mL1.4516 mL2.9032 mL14.5160 mL
50 mM0.1161 mL0.5806 mL1.1613 mL5.8064 mL
100 mM0.0581 mL0.2903 mL0.5806 mL2.9032 mL

SCI 文献

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法:
TargetMol | Animal experiments比如您的给药剂量是 10 mg/kg ,每只动物体重 20 g ,给药体积 100 μLTargetMol | Animal experiments 一共给药动物 10 只 ,您使用的配方为 5% TargetMol | reagent DMSO+ 30%PEG300+ 5%Tween 80 + 60% ddH2O. 那么您的工作液浓度为 2 mg/mL
母液配置方法: 2 mg 药物溶于 50 μLDMSOTargetMol | reagent ( 母液浓度为 40 mg/mL ), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:50μLDMSOTargetMol | reagent 母液,添加 300 μLPEG300TargetMol | reagent 混匀澄清,再加 50μLTween 80, 混匀澄清,再加 600μLddH2OTargetMol | reagent 混匀澄清

以上为“体内实验配液计算器”的使用方法举例,并不是具体某个化合物的推荐配制方式,请根据您的实验动物和给药方式选择适当的溶解方案。

1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成,不同的产品配方组成不同,如有配方需求,可先联系我们提供正确的体内配方。
% DMSO
%
%Tween 80
%ddH2O

剂量转换

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