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顶部生物活性储存和溶解信息计算器

Arachidonoyl-L-carnitine (chloride)

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Arachidonoyl-L-carnitine (chloride)
产品编号 T37407Cas号 2133455-98-6
别名 C20:4 Carnitine​, Arachidonoyl-L-carnitine (chloride)

Carnitine facilitates the transport of fatty acids into the mitochondria to be used in fatty acid metabolism. It does so by accepting acyl groups from fatty acids complexed with coenzyme A, which yields esterified carnitine or acylcarnitines that enable the transport of fatty acyl groups into the inner mitochondrial matrix. β-Oxidation of fatty acids in mitochondria is inhibited by uncoupling conditions, thus changes in circulating levels of various acylcarnitines have been used to identify alterations in metabolic state.[1] [2] Arachidonoyl-L-carnitine formed from carnitine conjugated to arachidonic acid .

Arachidonoyl-L-carnitine (chloride)

Arachidonoyl-L-carnitine (chloride)

Rating icon 还可以
Arachidonoyl-L-carnitine (chloride)
产品编号 T37407 别名 C20:4 Carnitine​, Arachidonoyl-L-carnitine (chloride)Cas号 2133455-98-6

Carnitine facilitates the transport of fatty acids into the mitochondria to be used in fatty acid metabolism. It does so by accepting acyl groups from fatty acids complexed with coenzyme A, which yields esterified carnitine or acylcarnitines that enable the transport of fatty acyl groups into the inner mitochondrial matrix. β-Oxidation of fatty acids in mitochondria is inhibited by uncoupling conditions, thus changes in circulating levels of various acylcarnitines have been used to identify alterations in metabolic state.[1] [2] Arachidonoyl-L-carnitine formed from carnitine conjugated to arachidonic acid .

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10 mg
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¥ 2,598
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50 mg
¥ 4,180
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生物活性
产品描述
Carnitine facilitates the transport of fatty acids into the mitochondria to be used in fatty acid metabolism. It does so by accepting acyl groups from fatty acids complexed with coenzyme A, which yields esterified carnitine or acylcarnitines that enable the transport of fatty acyl groups into the inner mitochondrial matrix. β-Oxidation of fatty acids in mitochondria is inhibited by uncoupling conditions, thus changes in circulating levels of various acylcarnitines have been used to identify alterations in metabolic state.[1] [2] Arachidonoyl-L-carnitine formed from carnitine conjugated to arachidonic acid .
别名C20:4 Carnitine​, Arachidonoyl-L-carnitine (chloride)
化学信息
分子量484.11
分子式C27H46ClNO4
CAS No.2133455-98-6
Smiles[C@H](OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)(C[N+](C)(C)C)CC(O)=O.[Cl-]
储存&溶解度
存储store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
溶解度信息
Ethanol: 30.00 mg/mL (61.97 mM), Sonication is recommended.
DMF: 20.00 mg/mL (41.31 mM), Sonication is recommended.
DMSO: 10.00 mg/mL (20.66 mM), Sonication is recommended.
PBS (pH 7.2): 10.00 mg/mL (20.66 mM), Sonication is recommended.
溶液配制表
DMSO/PBS (pH 7.2)/DMF/Ethanol
1mg5mg10mg50mg
1 mM2.0656 mL10.3282 mL20.6565 mL103.2823 mL
5 mM0.4131 mL2.0656 mL4.1313 mL20.6565 mL
10 mM0.2066 mL1.0328 mL2.0656 mL10.3282 mL
20 mM0.1033 mL0.5164 mL1.0328 mL5.1641 mL

计算器

  • 摩尔浓度 计算器
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  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

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TargetMol | Animal experiments比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， TargetMol | Animal experiments 一共给药动物 10 只 ，您使用的配方为 5% TargetMol | reagent DMSO+ 30%PEG300+ 5%Tween 80 + 60%Saline/PBS/ddH2O， 那么您的工作液浓度为 2 mg/mL 。
母液配置方法: 2 mg 药物溶于 50 μLDMSOTargetMol | reagent （ 母液浓度为 40 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。
体内配方的制备方法: 取 50μLDMSOTargetMol | reagent 母液，添加 300 μLPEG300TargetMol | reagent 混匀澄清，再加 50μLTween 80, 混匀澄清，再加 600μLSaline/PBS/ddH2OTargetMol | reagent 混匀澄清

以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。

1 请输入动物实验的基本信息
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2 请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。
% DMSO
%
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% Saline/PBS/ddH2O

剂量转换

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关键词

C20:4 CarnitineArachidonoylLcarnitine (chloride)Arachidonoyl-L-carnitineArachidonoyl L carnitine (chloride)

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