Strictosidinic acid has an antiradical action against DPPH, it has a promising effect in the central nervous system.

In a DPPH radical scavenging assay, Strictosidinic acid and barakol were more potent than the positive control, BHT. The EC50 values of Strictosidinic acid and barakol were 27.68 and 39.62 μM, respectively. Other tested compounds, including lawsone methyl ether, bergenin, homorapanone and lucidin-??-methyl ether, had weak antioxidative activities or no activity. In a nitrite assay, only lawsone methyl ether reduced nitrite production with an EC50 of 10.27 μM in RAW 264.7 cells.