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HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe that demonstrates exceptional sensitivity and selectivity in detecting hypochlorous acid. Its absorption wavelength is significantly longer than that of fluorescein-based probes, and it exhibits better pH stability. Notably, HKOCl-4 exhibits excitation at 530 nm and emission at 557 nm.
HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe that demonstrates exceptional sensitivity and selectivity in detecting hypochlorous acid. Its absorption wavelength is significantly longer than that of fluorescein-based probes, and it exhibits better pH stability. Notably, HKOCl-4 exhibits excitation at 530 nm and emission at 557 nm.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | ¥ 9,003 | 期货 |
产品描述 | HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe that demonstrates exceptional sensitivity and selectivity in detecting hypochlorous acid. Its absorption wavelength is significantly longer than that of fluorescein-based probes, and it exhibits better pH stability. Notably, HKOCl-4 exhibits excitation at 530 nm and emission at 557 nm. |
体外活性 | HKOCl-4 (10 μM) shows an increasing florescence intensity with increasing concentration of hypochlorous acid[1]. HKOCl-4 exhibits a ultra-fast response towards 1 equiv of HOCl (reached a plateau within 2 min) , and it shows a >20-fold increase in fluorescence intensity over other analytes (1 equiv of ?OH and ONOO? as well as 10 equiv of O2, NO, 1O2, ROO?, TBHP and H2O2)[2]. HKOCl-4 is first tested and it was proven to be non-toxic in living cells even at a concentration up to 50 μM in RAW264.7 macrophages[2]. |
别名 | HKOCl-4, BXY2142 |
分子量 | 688.6 |
分子式 | C38H35Cl2NO7 |
CAS No. | 2031170-85-9 |
密度 | 1.43 g/cm3 (Predicted) |
存储 | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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