NIR-FP is a near-infrared (NIR) fluorescent probe that exhibits high sensitivity and selectivity toward the superoxide anion (O2-), a principal precursor of reactive oxygen species (ROS). This probe facilitates dynamic monitoring of ferroptosis-mediated epilepsy models, which encompass the kainic acid-induced chronic epilepsy model, the pentylenetetrazole-induced acute epilepsy model, and the pilocarpine-induced epilepsy model [1].