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Search Results for " 6-nitrogen "

Targets Recommended: Nucleoside Antimetabolite/Analog Influenza Virus DNA/RNA Synthesis Antibacterial

6

抑制剂 & 化合物

2

天然产物

13

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T8648	6-AZATHYMINE	Nucleoside Antimetabolite/Analog; Influenza Virus; DNA/RNA Synthesis; Antibacterial	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	6-Azathymine 是胸腺嘧啶的 6-氮类似物，是 D-3-氨基异丁酸酯-丙酮酸氨基转移酶抑制剂，具有抗菌和抗病毒活性，可抑制DNA 的生物合成。
T35996	FeTPPS	Others	Others
	Peroxynitrite is a highly reactive nitrogen species formed from the reaction of nitric oxide (NO) and superoxide.[1] FeTPPS is a ferric porphyrin complex that causes the decomposition of peroxynitrite by catalytic isomerization to produce nitrate both in vitro and in vivo. The conversion of this reactive nitrogen species to nitrate results in cytoprotection (EC50 = 5 &#181M). [2][3] FeTPPS does not complex with NO and does not alter superoxide directly. It is commonly used to elucidate the roles...
T36175	AAPH	Others	Others
	AAPH is a water-soluble azo compound which is used extensively as a free radical generator, often in the study of lipid peroxidation and the characterization of antioxidants.[1],[2],[3],[4] Decomposition of AAPH produces molecular nitrogen and 2 carbon radicals. The carbon radicals may combine to produce stable products or react with molecular oxygen to give peroxyl radicals. The half-life of AAPH is about 175 hours (37°C at neutral pH), making the rate of free radical generation essentially con...
T68182	3-Hydroxykynurenamine	Others	Others
	3-Hydroxykynurenamine, also known as 3-Hydroxy-L-kynurenamine or 3-HKA, is a biogenic amine produced via an alternative pathway of tryptophan metabolism. In vitro, 3-HKA has an anti-inflammatory profile by inhibiting the IFN-γ mediated STAT1/NF-κΒ pathway in both mouse and human dendritic cells (DCs) with a consequent decrease in the release of pro-inflammatory chemokines and cytokines, most notably TNF, IL-6, and IL12p70. 3-HKA has protective effects in an experimental mouse model of psoriasis ...
T83735	Pap12-6 TFA
	Pap12-6是一种从蝶类P. xuthus幼虫中发现的papiliocin十二个N-端氨基酸衍生的抗菌肽。它对包括E. coli、P. aeruginosa和S. syphimurium在内的八种革兰氏阴性细菌（MIC50s = 4-8 µM）以及革兰氏阳性细菌S. aureus、耐甲氧西林的S. aureus 3126（MRSA-3126）、B. subtilis和S. epidermidis（MIC50s = 4-8 µM）具有活性，但在25 µM浓度下不影响人类红细胞、小鼠RAW 264.7巨噬细胞、人类HaCaT角质形成细胞或人类HEK293肾细胞的活性。Pap12-6在4和8 µM浓度下可引起E. coli的膜去极化。Pap12-6（10 µM）预处理可降低LPS刺激的RAW 264.7巨噬细胞中一氧化氮（NO2-）、Tnf-α和Il-6的分泌水平。在体内，Pap12-6（10 mg/kg）可以提高感染E. coli的小鼠的存活率，并且在剂量为1 mg/kg时减少感染E. coli小鼠的肺、肝和肾中菌落形成单位（CFUs）的数量。Pap12-6（1 mg/kg）在E. co...
T37741	N-hexadecanoyl-L-Homoserine lactone C16-HSL,N-palmitoyl-L-Homoserine,N-hexadecanoyl-L-Homoserine lactone	Others	Others
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.[2] Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which...

化合物

Cat.No: T8648

Target: Nucleoside Antimetabolite/Analog, Influenza Virus, DNA/RNA Synthesis, Antibacterial

Cat.No: T35996

Target: Others

Cat.No: T36175

Target: Others

3-Hydroxykynurenamine

Cat.No: T68182

Target: Others

Cat.No: T83735

N-hexadecanoyl-L-Homoserine lactone

Cat.No: T37741

Synonym: C16-HSL,N-palmitoyl-L-Homoserine,N-hexadecanoyl-L-Homoserine lactone

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T6S0139	Neobavaisoflavone	Apoptosis; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Neobavaisoflavone 是一种从Psoralea corylifolia 的种子中分离出来的类黄酮。它具有抗炎，抗癌和抗氧化的作用。它在中至高浓度下可抑制 DNA 聚合酶，也可抑制血小板聚集。
T82799	C-2′-Decoumaroylaloeresin G
	C-2′-Decoumaroylaloeresin G (化合物8)为一种色酮糖苷，源自芦荟属植物。

天然产物

Neobavaisoflavone

Cat.No: T6S0139

Target: Apoptosis, DNA/RNA Synthesis

C-2′-Decoumaroylaloeresin G

Cat.No: T82799

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01189	GFPT1 Protein, Human, Recombinant GFAT1,CMSTA1,GFAT,glutamine--fructose-6-phosphate t...	Human	E. coli
	Glutamine:fructose-6-phosphate amidotransferase 1 (GFAT), also known as GFPT1, is a member of the N-terminal nucleophile aminotransferases and the first rate-limiting enzyme for the entry of glucose into the hexosamine biosynthesis pathway (HBP) in mammals. GFAT transfers the amino group from the L-glutamine amide to the D-fructose 6-phosphate, producing glutamic acid and glucosamine 6-phosphate. GFAT exists as a homotetramer in cytoplasm, and is proposed to be most likely involved in re...
TMPJ-00567	NCR1 Protein, Human, Recombinant (hFc) hNKp46,Natural cytotoxicity triggering receptor 1,N...	Human	HEK293 Cells
	Natural cytotoxicity triggering receptor 1(NCR1) is a single-pass type I membrane protein .It contains 2 Ig-like (immunoglobulin-like) domains and belongs to the natural cytotoxicity receptor (NCR) family. The protein is a natural killer (NK) lymphocyte-activating receptor. It is involved in major aspects of NK immune function and shows a high degree of lineage specificity in blood and bone marrow.
TMPY-03128	LAIR1 Protein, Mouse, Recombinant (hFc) leukocyte-associated immunoglobulin-like receptor 1,BB1152	Mouse	HEK293 Cells
	LAIR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.6 kDa and the accession number is Q8BG84-6.
TMPJ-00827	Tau-D Protein, Human, Recombinant (His) PHF-Tau,MAPTL,MAPT,Paired Helical Filament-Tau,Microtubule-A...	Human	E. coli
	Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere, but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. Tau interacts with tubulin to stabilize microtubules and promotes tubulin assembly into microtubules. The C-terminus of TAU binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau acts as a linker protein. When tau is defective,...
TMPY-05798	VEGF145 Protein, Human, Recombinant 血管内皮生长因子,vascular endothelial growth factor A,VPF,MVCD1,VEGF...	Human	HEK293 Cells
	VEGF145 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16.92 kDa and the accession number is P15692-6.
TMPY-04277	CD45 Protein, Mouse, Recombinant (hFc) Cd45,protein tyrosine phosphatase, receptor type, C,Ly-5,L-C...	Mouse	HEK293 Cells
	CD45 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.7 kDa and the accession number is P06800-6.
TMPY-02600	NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc) neuregulin 1,HRGA,NRG1 β1,HGL,MST131,MSTP131,HRG,ARIA,NDF,GG...	Human	HEK293 Cells
	NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 36.7 kDa and the accession number is Q02297-6.
TMPY-02705	NRG1 beta 1 Protein, Human, Recombinant (hFc) MSTP131,HRG1,NRG1-IT2,ARIA,HGL,SMDF,GGF,HRG,NDF,MST131,neure...	Human	HEK293 Cells
	NRG1 beta 1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 55.2 kDa and the accession number is Q02297-6.
TMPY-03010	NRG1 beta 1 Protein, Human, Recombinant NDF,GGF,MSTP131,Neuregulin 1,MST131,ARIA,NRG1-IT2,SMDF,NRG1 ...	Human	HEK293 Cells
	NRG1 beta 1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.8 kDa and the accession number is Q02297-6.
TMPK-00614	NKp46/NCR1 Protein, Human, Recombinant (His) NKp46,MAR-1,Ly94,NCR1,NKP46FLJ99094,CD335	Human	HEK293 Cells
	NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells. NKp46/NCR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 27.5 kDa and the accession numb...
TMPK-00615	NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated CD335,NCR1,NKp46,NKP46FLJ99094,Ly94,MAR-1	Human	HEK293 Cells
	NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells. NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular we...
TMPK-01364	SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated SIRP α,MFR,SHPS1,SIRPA,BIT,SHPS-1,MYD-1,SIRP alpha,P84,CD172...	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c...
TMPK-01358	SIRP alpha V6 Protein, Human, Recombinant (His & Avi) P84,SIRPA,SIRP alpha,SHPS-1,MFR,BIT,MYD1,SIRP α V6,...	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V6 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi...

重组蛋白

GFPT1 Protein, Human, Recombinant

Cat.No: TMPY-01189

Species: Human

Expression System: E. coli

NCR1 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00567

Species: Human

Expression System: HEK293 Cells

LAIR1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-03128

Species: Mouse

Expression System: HEK293 Cells

Tau-D Protein, Human, Recombinant (His)

Cat.No: TMPJ-00827

Species: Human

Expression System: E. coli

VEGF145 Protein, Human, Recombinant

Cat.No: TMPY-05798

Species: Human

Expression System: HEK293 Cells

CD45 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-04277

Species: Mouse

Expression System: HEK293 Cells

NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc)

Cat.No: TMPY-02600

Species: Human

Expression System: HEK293 Cells

NRG1 beta 1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02705

Species: Human

Expression System: HEK293 Cells

NRG1 beta 1 Protein, Human, Recombinant

Cat.No: TMPY-03010

Species: Human

Expression System: HEK293 Cells

NKp46/NCR1 Protein, Human, Recombinant (His)

Cat.No: TMPK-00614

Species: Human

Expression System: HEK293 Cells

NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

Cat.No: TMPK-00615

Species: Human

Expression System: HEK293 Cells

SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01364

Species: Human

Expression System: HEK293 Cells

SIRP alpha V6 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-01358

Species: Human

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
T70313	Indoxyl Sulfate-d5 potassium salt
	Indoxyl sulfate-d5 is intended for use as an internal standard for the quantification of indoxyl sulfate by GC- or LC-MS. Indoxyl sulfate is a uremic toxin and a metabolite of tryptophan. It is formed via sulfation of indole, an intermediate generated from tryptophan by intestinal bacteria, by the sulfotransferase (SULT) isoform 1A1 variant 2 (SULT1A1*2) in the liver. Indoxyl sulfate activates the aryl hydrocarbon receptor (AhR) in HepG2 40/6 hepatoma cells (EC50 = 12.1 nM in a reporter assay). ...

同位素标记化合物

Indoxyl Sulfate-d5 potassium salt

Cat.No: T70313

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