PROTAC RIPK degrader-6

Name: PROTAC RIPK degrader-6
Brand: TargetMol
SKU: T36243
Rating: 4.5 (1 reviews)

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产品编号 T36243Cas号 2089205-64-9

PROTAC RIPK degrader-6 (example 1) is a PROTAC designed for the targeted degradation of RIP Kinase, featuring a RIP2 kinase inhibitor connected through a linker to a cereblon binder[1].

PROTAC RIPK degrader-6

还可以

产品编号 T36243Cas号 2089205-64-9

PROTAC RIPK degrader-6 (example 1) is a PROTAC designed for the targeted degradation of RIP Kinase, featuring a RIP2 kinase inhibitor connected through a linker to a cereblon binder[1].

规格	价格	库存
5 mg	¥ 4,665	期货
10 mg	¥ 6,852	期货
25 mg	¥ 12,522	期货
1 mL x 10 mM (in DMSO)	¥ 6,698	期货

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生物活性

产品描述	PROTAC RIPK degrader-6 (example 1) is a PROTAC designed for the targeted degradation of RIP Kinase, featuring a RIP2 kinase inhibitor connected through a linker to a cereblon binder[1].
体外活性	PROTACs is useful for the targeted degradation of proteins and other polypeptides which on the one end binds to the cereblon and on the other end to the target protein (RIP2 kinase). By bringing the target protein in close proximity to the E3-Ligase, these compounds form a ternary complex leading to polyubiquitination of the target protein inducing its degradation[1].

化学信息

分子量	889.01
分子式	C₄₃H₄₈N₆O₁₁S₂
CAS No.	2089205-64-9

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

溶解度信息

DMSO: 100 mg/mL (112.49 mM)

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.1248 mL	5.6242 mL	11.2485 mL	56.2423 mL
5 mM	0.2250 mL	1.1248 mL	2.2497 mL	11.2485 mL
10 mM	0.1125 mL	0.5624 mL	1.1248 mL	5.6242 mL
20 mM	0.0562 mL	0.2812 mL	0.5624 mL	2.8121 mL
50 mM	0.0225 mL	0.1125 mL	0.2250 mL	1.1248 mL
100 mM	0.0112 mL	0.0562 mL	0.1125 mL	0.5624 mL