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GSK9311 hydrochloride, a less active analog of GSK6853, can be used as a negative control. GSK9311 hydrochloride inhibits BRPF bromodomain (pIC50s: 6.0 and 4.3 for BRPF1 and BRPF2).
GSK9311 hydrochloride, a less active analog of GSK6853, can be used as a negative control. GSK9311 hydrochloride inhibits BRPF bromodomain (pIC50s: 6.0 and 4.3 for BRPF1 and BRPF2).
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥ 1,500 | 35日内发货 |
产品描述 | GSK9311 hydrochloride, a less active analog of GSK6853, can be used as a negative control. GSK9311 hydrochloride inhibits BRPF bromodomain (pIC50s: 6.0 and 4.3 for BRPF1 and BRPF2). |
靶点活性 | BRPF2:4.3(pIC50), BRPF1:6(pIC50) |
体外活性 | GSK6853 is a less active analogue of GSK6853 in which the 5-amide is alkylated.GSK6853 is a potent (300 pM), soluble, cell active (20 nM), and highly selective inhibitor of the BRPF1 bromodomain, and demonstrates properties suitable for cellular and in vivo studies. |
分子量 | 474 |
分子式 | C24H32ClN5O3 |
CAS No. | 2253733-09-2 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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