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Targets Recommended: Factor Xa CRFR

1533

抑制剂 & 化合物

349

天然产物

11

化合物库

1653

重组蛋白

16

同位素标记化合物

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Cat. No.	Product Name
L1380	转录因子库		695 compounds
	695 种转录因子靶向、结构新颖的化合物；
L8500	HIF-1化合物库		1336 compounds
	1336 个HIF-1相关小分子的独特集合，可用于缺血性疾病、癌症等相关领域的药物开发和药理研究；
L4100	TGF-β/Smad靶点化合物库		184 compounds
	184 个 TGF-β/Smad 靶点相关的小分子化合物的特有集合，用于高通量、高内涵筛选；
L2193	抗肝癌化合物库		1787 compounds
	1787 种与肝癌相关的化合物，可以用于抗肝癌药物研发和药理研究；
L2191	抗乳腺癌化合物库		1939 compounds
	1939 种与乳腺癌相关的化合物，可以用于抗乳腺癌药物研发和药理研究；
L9830	抗帕金森病化合物库		857 compounds
	857 种帕金森病相关的化合物集合，可用于高通量和高内涵筛选；
L3800	NF-κB 通路分子库		729 compounds
	729 个 NF-κB 信号通路相关的小分子化合物的特有集合，用于高通量、高内涵筛选；
L6750	活血化瘀中药单体库		580 compounds
	580种来源于常见活血化瘀中药的单体化合物，是药物开发、药理研究等领域的有效工具。
L2550	谷氨酰胺代谢化合物库		565 compounds
	565 种谷氨酰胺代谢相关的分子，可以用于高通量和高内涵筛选；
L7110	抗高血压化合物库		678 compounds
	678 种高血压相关的小分子，用于高通量和高内涵筛选；
DO1200	药物靶点库		53200 compounds
	数量多，含53200种小分子化合物，是高通量筛选的有力工具；

化合物库

转录因子库

Cat.No: L1380

Compounds: 695

HIF-1化合物库

Cat.No: L8500

Compounds: 1336

TGF-β/Smad靶点化合物库

Cat.No: L4100

Compounds: 184

抗肝癌化合物库

Cat.No: L2193

Compounds: 1787

抗乳腺癌化合物库

Cat.No: L2191

Compounds: 1939

抗帕金森病化合物库

Cat.No: L9830

Compounds: 857

NF-κB 通路分子库

Cat.No: L3800

Compounds: 729

活血化瘀中药单体库

Cat.No: L6750

Compounds: 580

谷氨酰胺代谢化合物库

Cat.No: L2550

Compounds: 565

抗高血压化合物库

Cat.No: L7110

Compounds: 678

药物靶点库

Cat.No: DO1200

Compounds: 53200

Cat. No.	Product Name	Target	Signaling Pathways
TP1144L	Corticotropin-releasing factor (human) acetate Corticotropin-releasing factor (human) acetate (86784-80-7 Free base)	CRFR	GPCR/G Protein
	Corticotropin-releasing factor (human) acetate 刺激垂体前叶合成和分泌促肾上腺皮质激素。
T38332	Complement factor D-IN-2	Complement System	Immunology/Inflammation
	Complement factor D-IN-2 是 omplement factor D 的有效抑制剂，在替代补体途径的早期和关键时刻靶向 factor D 并抑制补体级联反应。Complement factor D-IN-2在自身免疫疾病的方面有研究的价值。
TP1106L	α-Factor Mating Pheromone, yeast acetate Mating Factor α acetate,α-Factor Mating Pheromone, yeast acetate(59401-28-4 free base)	Others	Others
	α-Factor Mating Pheromone, yeast acetate (Mating Factor α acetate)(59401-28-4 free base) 是由酿酒酵母α细胞分泌的13个氨基酸的肽。
T8679	Epidermal Growth Factor	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Epidermal Growth Factor 与表皮生长因子受体 (EGFR) 结合并刺激细胞生长和增殖。它被批准用于治疗糖尿病足溃疡。
TP1155L	Human growth hormone-releasing factor acetate	GHSR	GPCR/G Protein
	Human growth hormone-releasing factor acetate 是一种下丘脑多肽，通过与垂体前叶细胞上的 GHRH 受体 (GHRHR) 结合来刺激 GH 的产生和释放。
T12218	NFAT Transcription Factor Regulator-1	IL Receptor	Immunology/Inflammation
	NFAT Transcription Factor Regulator-1 是 IL-2 合成的抑制剂，IC50 值为182 nM。
T28869	Streptomyces A-Factor A-Factor (Lactone)	Others	Others
	Streptomyces A-Factor is a microbial hormone found in Streptomyces griseus. A-factor triggers streptomycin biosynthesis and cell differentiation by binding a repressor-type receptor protein (ArpA) and dissociating it from DNA.
T36523	Extracellular Death Factor
	Programmed cell death in bacteria is dependent on a system of cell-to-cell communication termed quorum sensing. Extracellular death factor (EDF) is a linear pentapeptide that communicating cells produce and release, which upon reaching a sufficient concentration activates the cell death pathway in a subset of cells. It is sensitive to extreme pH, high temperatures, and other stressful conditions. At 2.5 ng/ml, EDF has been shown to facilitate mazEF-mediated cell death, significantly reducing pop...
T30743	Carbon dioxide reduction factor Methanofuran,Cdr factor	Others	Others
	Carbon dioxide reduction factor is a coenzyme of methanogenesis from carbon dioxide.
TP1144	Corticotropin-releasing factor (human) Human corticotropin-releasing factor,Human CRF,Corticotropin-releasing factor human
	Corticotropin-releasing factor human (Human CRF; Human corticotropin-releasing factor) is an immunomodulatory neuropeptide that acts to release ACTH from the anterior pituitary and stimulates the sympathetic nervous system and adrenal medulla. Functions b
T38969	Factor B-IN-1	Others	Others
	Factor B-IN-1 is a Factor B inhibitor.
TP1106	α-Factor Mating Pheromone, yeast Mating Factor α
	Alpha factor mating pheromone is a peptide of 13 amino acids secreted by Saccharomyces cerevisiae α cells.
T38803	Factor D inhibitor 6	Others	Others
	Factor D inhibitor 6 is a potent, highly selective, orally active compound that specifically inhibits the activity of factor D (FD). It demonstrates an IC50 of 30 nM and a Kd of 6 nM. Notably, Factor D inhibitor 6 does not exhibit any inhibitory effects against factor B, classical and lectin complement-pathway activation, nor does it interfere with a broad array of receptors, ion channels, kinases, and proteases.
T40459	Transcriptional Intermediary Factor 2 (TIF2) (740-753) Transcriptional Intermediary Factor 2 (TIF2) (740-753)
	Transcriptional Intermediary Factor 2 (TIF2) (740-753) is a 14-amino acid peptide that serves as a coactivator of TIF-2 protein. It specifically covers residues 740-753 of the TIF-2 protein.
TP1155	Human growth hormone-releasing factor Growth Hormone Releasing Factor human
	Human growth hormone-releasing factor stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary.Growth hormone-releasing hormone is a hormone produced in the hypothalamus. The main role of growth hormo
T37111	Corticotropin-releasing factor (human) (acetate)
	Human CRF acetate is a chemical compound that effectively stimulates the synthesis and secretion of adrenocorticotropin in the anterior pituitary.
T41065	Atrial natriuretic factor (1-28) (human, porcine) Atrial natriuretic factor (1-28) (human, porcine),Atrial natriuretic peptide (1-28)
	Atrial natriuretic factor (1-28) from both human and porcine sources is a powerful suppressor of pro-opiomelanocortin (POMC) mRNA, while it only has a modest inhibition effect on βEP-LI release.
T19750	Spinosad Factor D	Others	Others
	Spinosad Factor D is a naturally derived fermentation product. It is used as a pesticide against many different insects.
TP1105	α-Factor Mating Pheromone, yeast (TFA) α-Factor Mating Pheromone, yeast (TFA)(59401-28-4,FREE),Mating Factor α (TFA)
	The alpha factor pheromone arrests yeast in the G1 phase of their cell cycle. Alpha Factor Mating Pheromone induces the expression of mating genes, changes in nuclear architecture, and polarzes growth toward the mating partner.
TP1030	Thymus factor X TFX-Jelfa,胸腺因子X
	Thymic factor X (TFX-Jelfa) is an aqueous extract from the thymus of a juvenile calf and is a natural stimulator of lymphocyte function.
T80986	Thymus Factor
	Thymus Factor 是重要的生化物质，负责促进体液免疫功能的成熟。
T31742	Factor 390 A F390-A,F390A,P-5-(S)-N-(N-(1-Oxo-2-(phosphonooxy)propyl)-L-gamma-glutamyl)-L-glutamate,F390 A	Others	Others
	Factor 390 A is a phosphodiester between AMP & methanogen factor 420.
T16898	Complement factor D-IN-1	Others	Others
	Complement factor D-IN-1 is an effective and selective small-molecule reversible factor d inhibitor (IC50s: 0.006 and 0.05 μM in FD Thioesterolytic Fluorescent Assay and a MAC Deposition Assay, respectively).
TP2247	eukaryotic translation initiation factor 3	Others	Others
	Eukaryotic initiation factors (eIF) are proteins involved in the initiation phase of eukaryotic translation. Eukaryotic translation initiation factor 3 binds to the ribosome subunit-mRNA complex. It has been implicated in preventing the large ribosomal subunit from binding the small subunit before it is ready to commence elongation.
T8680	FIBROBLAST GROWTH FACTOR, BASIC, HUMAN
	FIBROBLAST GROWTH FACTOR, BASIC, HUMAN 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T8680，CAS号为 62031-54-3。
T80059	Complement factor I	Endogenous Metabolite	Metabolism
	Complement factor I，一丝氨酸蛋白酶，可与辅助因子H (FH)、补体受体1 (CR1/CD35)、C4结合蛋白 (C4BP) 或膜辅助因子蛋白 (MCP/CD46) 结合，调控液相及/或细胞表面补体系统的活性。
TP2466	Platelet factor 4 (59-70) PF4 (59-70)
	Platelet factor 4 (59-70) elicits human neutrophil & monocyte chemotaxis.
TP1667	Platelet Factor 4 (58-70), human
	Platelet Factor 4 (58-70), human is a polypeptide based on the 58-70 amino acid sequence of Platelet Factor 4 (pf-4) residues.
T125686	Euphorbia factor L22	Others	Others
	Euphorbia factor L22 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125686。
T126086	Euphorbia factor L9	Others	Others
	Euphorbia factor L9 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126086。
T125685	Euphorbia factor L24	Others	Others
	Euphorbia factor L24 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125685。
TP1122L	IGF-I 30-41 acetate(82177-09-1 free base) Insulin-like Growth Factor I (30-41) acetate	Others	Others
	IGF-I 30-41 acetate(82177-09-1 free base) (Insulin-like Growth Factor I (30-41) acetate) 是胰岛素样生长因子 I (IGF-I) 的氨基酸 30 至 41 片段。
T125089	Euphorbia factor L25	Others	Others
	Euphorbia factor L25 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125089。
T63234	Factor XI-IN-1	Others	Others
	Factor XI-IN-1 是 factor XI 活化 (factor XI activation) 抑制剂(EC50: 25.14 nM)。
T62276	Factor B-IN-3	Others	Others
	Factor B-IN-3 是一种补体因子 B (complement factor B) 的有效抑制剂。Factor B-IN-3 能够用于研究炎症和免疫相关疾病。
T37820	Brain-Derived Basic Fibroblast Growth Factor (1-24) (bovine) (trifluoroacetate salt)
	Brain-derived basic fibroblast growth factor (1-24) (brain-derived bFGF) is a peptide fragment of brain-derived bFGF. bFGF is a peptide produced in bovine brain that is protective in a rat model of pressure-induced retinal ischemia. bFGF (1-24) corresponds to amino acid residues 1-24 of the full length peptide.
T37595	Brain-Derived Acidic Fibroblast Growth Factor (1-11) (bovine) (trifluoroacetate salt)
	Brain-derived acidic fibroblast growth factor (brain-derived aFGF) (1-11) is a peptide fragment of brain-derived aFGF. Brain-derived aFGF is an angiogenic vascular endothelial cell mitogen produced in bovine brain that has sequence homology to interleukin-1. aFGF (1-11) corresponds to amino acid residues 1-11 of the full length peptide.
T60991	Factor VII-IN-1	Others	Others
	Factor VII-IN-1 (example 43) 具有抗凝血活性，它是一种有效的因子 VII (FVII) 的抑制剂，IC50值为1.1 μM。
T37819	Brain-Derived Acidic Fibroblast Growth Factor (102-111) (bovine) (trifluoroacetate salt)
	Brain-derived acidic fibroblast growth factor (102-111) is a peptide fragment of brain-derived acidic fibroblast growth factor (aFGF). aFGF is an angiogenic vascular endothelial cell mitogen produced in bovine brain that has sequence homology to interleukin-1. It also shares sequence homology with the known neuropeptides neuromedin C , bombesin , neuromedin K , substance K , substance P , physalaemin, and eledoisin. aFGF (102-111) corresponds to amino acid residues 102-111 of the fulllength pept...
T62292	Factor B-IN-2	Others	Others
	Factor B-IN-2 是一种补体因子 B (complement factor B) 的有效抑制剂 (IC50: 1.5 μM)。Factor B-IN-2 能够用于研究炎症和免疫相关疾病。
T62688	Factor B-IN-4	Others	Others
	Factor B-IN-4 是一种补体因子 B (complement factor B) 的有效抑制剂 (IC50: 1 μM)。Factor B-IN-4 能够用于研究炎症和免疫相关疾病。
T62689	Factor B-IN-5	Others	Others
	Factor B-IN-5 是一种补体因子 B (complement factor B) 的有效抑制剂 (IC50: 1.2 μM)。Factor B-IN-4 能够用于研究炎症和免疫相关疾病。
T82458	Epigenetic factor-IN-1	Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Epigenetic factor-IN-1（40569Z）是一种针对SIRT7显示出强效结合能力的表观遗传因子抑制剂，常用于肝癌的研究领域。
TP1218	Atrial natriuretic factor (1-28) (rat) TFA Atrial Natriuretic Peptide (ANP) (1-28), rat TFA
	Atrial Natriuretic Peptide (ANP) (1-28),rat (TFA) is the main circulating forms of Atrial Natriuretic Peptide (ANP) in rats, which strongly inhibit the secretion of Ang II - stimulated endothelin-1.
TP2229	Epidermal growth factor receptor (994-1002) acetyl/amide	Others	Others
	The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family of extracellular protein ligands.
TP2221L	ANP (1-11), rat acetate Atrial natriuretic factor (1-11) acetate,ANP (1-11), rat醋酸盐,Atriopeptide (1-11) acetate	Others	Others
	ANP (1-11), rat acetate (Atrial natriuretic factor (1-11) acetate) 是心房利钠因子之一，是 CRF 刺激的 ACTH 分泌的抑制剂。
T21723L	EGF Receptor Peptide Acetate EGF Receptor Peptide Acetate (96249-43-3 Free base),Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base)	Others	Others
	Epidermal Growth Factor Receptor Peptide Acetate (Epidermal Growth Factor Receptor Peptide Acetate (96249-43-3 Free base)) 存在于细胞表面，通过与其特异性配体的结合而被激活。EGFR 属于受体酪氨酸激酶(RTK) 的 ErbB 家族。
T76539	Insulin-like growth factor II	Others	Others
	Insulin-like growth factor II (IGF-2)为人血清中主要生长激素，对神经突生长具有许可性和直接作用，同时增强交感与感觉神经元的生存能力。
T60682	Elongation factor P-IN-2	Others	Others
	Elongation factor P-IN-2可影响大肠杆菌的增殖率。Elongation factor P-IN-2 是 β-赖氨酸衍生化合物，是延伸因子 P (EFP)的有效抑制剂。
T81087	Stick Insect Hypertrehalosaemic Factor II
	Stick Insect Hypertrehalosaemic Factor II为合成肽，展现出与天然样品一致的FAB光谱、反相高效液相色谱特性以及生物活性，适用于高海藻糖效应的研究。

化合物

Corticotropin-releasing factor (human) acetate

Cat.No: TP1144L

Synonym: Corticotropin-releasing factor (human) acetate (86784-80-7 Free base)

Target: CRFR

Complement factor D-IN-2

Cat.No: T38332

Target: Complement System

α-Factor Mating Pheromone, yeast acetate

Cat.No: TP1106L

Synonym: Mating Factor α acetate,α-Factor Mating Pheromone, yeast acetate(59401-28-4 free base)

Target: Others

Epidermal Growth Factor

Cat.No: T8679

Target: EGFR

Human growth hormone-releasing factor acetate

Cat.No: TP1155L

Target: GHSR

NFAT Transcription Factor Regulator-1

Cat.No: T12218

Target: IL Receptor

Streptomyces A-Factor

Cat.No: T28869

Synonym: A-Factor (Lactone)

Target: Others

Extracellular Death Factor

Cat.No: T36523

Carbon dioxide reduction factor

Cat.No: T30743

Synonym: Methanofuran,Cdr factor

Target: Others

Corticotropin-releasing factor (human)

Cat.No: TP1144

Synonym: Human corticotropin-releasing factor,Human CRF,Corticotropin-releasing factor human

Factor B-IN-1

Cat.No: T38969

Target: Others

α-Factor Mating Pheromone, yeast

Cat.No: TP1106

Synonym: Mating Factor α

Factor D inhibitor 6

Cat.No: T38803

Target: Others

Transcriptional Intermediary Factor 2 (TIF2) (740-753)

Cat.No: T40459

Synonym: Transcriptional Intermediary Factor 2 (TIF2) (740-753)

Human growth hormone-releasing factor

Cat.No: TP1155

Synonym: Growth Hormone Releasing Factor human

Corticotropin-releasing factor (human) (acetate)

Cat.No: T37111

Atrial natriuretic factor (1-28) (human, porcine)

Cat.No: T41065

Synonym: Atrial natriuretic factor (1-28) (human, porcine),Atrial natriuretic peptide (1-28)

Spinosad Factor D

Cat.No: T19750

Target: Others

α-Factor Mating Pheromone, yeast (TFA)

Cat.No: TP1105

Synonym: α-Factor Mating Pheromone, yeast (TFA)(59401-28-4,FREE),Mating Factor α (TFA)

Thymus factor X

Cat.No: TP1030

Synonym: TFX-Jelfa,胸腺因子X

Thymus Factor

Cat.No: T80986

Cat.No: T31742

Synonym: F390-A,F390A,P-5-(S)-N-(N-(1-Oxo-2-(phosphonooxy)propyl)-L-gamma-glutamyl)-L-glutamate,F390 A

Target: Others

Complement factor D-IN-1

Cat.No: T16898

Target: Others

eukaryotic translation initiation factor 3

Cat.No: TP2247

Target: Others

FIBROBLAST GROWTH FACTOR, BASIC, HUMAN

Cat.No: T8680

Complement factor I

Cat.No: T80059

Target: Endogenous Metabolite

Platelet factor 4 (59-70)

Cat.No: TP2466

Synonym: PF4 (59-70)

Platelet Factor 4 (58-70), human

Cat.No: TP1667

Euphorbia factor L22

Cat.No: T125686

Target: Others

Euphorbia factor L9

Cat.No: T126086

Target: Others

Euphorbia factor L24

Cat.No: T125685

Target: Others

IGF-I 30-41 acetate(82177-09-1 free base)

Cat.No: TP1122L

Synonym: Insulin-like Growth Factor I (30-41) acetate

Target: Others

Euphorbia factor L25

Cat.No: T125089

Target: Others

Factor XI-IN-1

Cat.No: T63234

Target: Others

Factor B-IN-3

Cat.No: T62276

Target: Others

Brain-Derived Basic Fibroblast Growth Factor (1-24) (bovine) (trifluoroacetate salt)

Cat.No: T37820

Brain-Derived Acidic Fibroblast Growth Factor (1-11) (bovine) (trifluoroacetate salt)

Cat.No: T37595

Factor VII-IN-1

Cat.No: T60991

Target: Others

Brain-Derived Acidic Fibroblast Growth Factor (102-111) (bovine) (trifluoroacetate salt)

Cat.No: T37819

Factor B-IN-2

Cat.No: T62292

Target: Others

Factor B-IN-4

Cat.No: T62688

Target: Others

Factor B-IN-5

Cat.No: T62689

Target: Others

Epigenetic factor-IN-1

Cat.No: T82458

Target: Sirtuin

Atrial natriuretic factor (1-28) (rat) TFA

Cat.No: TP1218

Synonym: Atrial Natriuretic Peptide (ANP) (1-28), rat TFA

Epidermal growth factor receptor (994-1002) acetyl/amide

Cat.No: TP2229

Target: Others

ANP (1-11), rat acetate

Cat.No: TP2221L

Synonym: Atrial natriuretic factor (1-11) acetate,ANP (1-11), rat醋酸盐,Atriopeptide (1-11) acetate

Target: Others

EGF Receptor Peptide Acetate

Cat.No: T21723L

Synonym: EGF Receptor Peptide Acetate (96249-43-3 Free base),Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base)

Target: Others

Insulin-like growth factor II

Cat.No: T76539

Target: Others

Elongation factor P-IN-2

Cat.No: T60682

Target: Others

Stick Insect Hypertrehalosaemic Factor II

Cat.No: T81087

Cat. No.	Product Name	Target	Signaling Pathways
TN1635	Euphorbia factor L8	Others	Others
	Euphorbia factor L8 是大戟种子中的二萜。
TN1634	Euphorbia factor L7b 千金子素L7B	Others	Others
	Euphorbia factor L7b 是从大戟属植物大戟中提取的天然产物。
TN1633	Euphorbia factor L7a	Others	Others
	Euphorbia factor L7a 是大戟种子中的二萜。
T2S0410	Euphorbia factor L1 Euphorbiasteroid,大戟因子L1,大戟因子 L1	Apoptosis; P-gp	Apoptosis; Membrane transporter/Ion channel; Neuroscience
	Euphorbia factor L1 (Euphorbiasteroid) 可降低 Bcl-2，PI3K，AKT 和 mTOR 蛋白和 mRNA 水平，上调 caspase-9 and caspase-3 蛋白水平。它可诱导自噬，具有抗癌、抗脂肪生成、抗破骨细胞生成和多重耐药调节作用。
T5798	Euphorbia Factor L2 千金子素L2,euphorbiafactor L2,大戟因子L2	Apoptosis; NF-κB	Apoptosis; NF-κB
	Euphorbia Factor L2 是从大戟种子中分离得到的一种赤藓烷二萜，显示强烈的细胞毒性并通过线粒体途径诱导细胞凋亡，具有抗癌活性。
T125211	Deoxy euphorbia factor L1	Others	Others
	Deoxy euphorbia factor L1是一种天然产物，存在于植物续随子 Euphorbia lathyris L 的种子中。
T78500	α-Factor Mating Pheromone, yeast TFA Mating Factor α TFA	Others	Others
	α-Factor Mating Pheromone, yeast (TFA)为一来自S. cerevisiae的α细胞分泌的十三肽，通过Ste2p受体发挥作用。
T3220	Euphorbiasteroid Euphobiasteroid,Euphorbia factor L1,千金子甾醇	Others; AMPK	Chromatin/Epigenetic; Others; PI3K/Akt/mTOR signaling
	Euphorbiasteroid (Euphobiasteroid) 是续随子中的一种三环二萜，可抑制酪氨酸酶活性，增强AMPK 的磷酸化。它通过减少细胞内甘油三酯的积累来降低 3T3-L1 细胞的分化，具有抗癌、抗病毒、抗肥胖及多重耐药调节作用。
T1255	Tobramycin NSC 180514,妥布霉素,Nebramycin Factor 6,Deoxykanamycin B	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Tobramycin (NSC-180514) 是一种胃肠外给药的广谱氨基糖苷类抗生素，可研究由于敏感生物引起的中度至重度细菌感染疾病。
TQ0099	20-O-Acetylingenol-3-angelate 巨大戟醇-3-O-当归酸-20-乙酸酯,Euphorbia factor Pe1	Others	Others
	20-O-Acetylingenol-3-angelate (Euphorbia factor Pe1) 是一种天然化合物，存在于植物英加的叶子和茎中。它具有多种生物活性，包括抑制肿瘤生长、抗炎、抗真菌和抗氧化作用。
T4S2014	5,15-Diacetyl-3-benzoyllathyrol ，大戟因子L3,二乙酰基苯甲酰基香豌豆醇,5,15-二乙酰基-3-苯甲酰千金子二萜醇；千金二萜醇二乙酰苯甲酰酯,Euphorbia factor L3	Others	Others
	5,15-Diacetyl-3-benzoyllathyrol (Euphorbia factor L3) 是一种具有抗癌作用的萜类化合物。
T5688	Micheliolide	NOS; NF-κB; COX	Immunology/Inflammation; Neuroscience; NF-κB
	Micheliolide 是一种倍半萜内酯，能够抑制各种炎症反应。它能减弱高糖刺激的NF-κB 活化，IκBα的降解，和MCP-1，TGF-β1，FN 在鼠系膜细胞的表达。
TN1131	Handelin	NF-κB; Immunology/Inflammation related	Immunology/Inflammation; NF-κB
	Handelin 是一种来自 Chrysanthemum boreale 的愈创木酚内酯二聚体，它能够阻碍 NF-κB 活化和促炎细胞因子产生，具有抗炎作用。
T4S0217	HOMOPLANTAGININ	TNF; NF-κB	Apoptosis; NF-κB
	Homoplantaginin 是来自中药荔枝草的一种类黄酮，具有抗炎和抗氧化活性。
T10383	Asatone	NF-κB	NF-κB
	Asatone 是一种从细辛中分离到的活性成分，通过活化 NF-κB 及下调 p-MAPK (ERK，JNK 和 p38) 通路起作用，具有抗炎作用。
T13686	Ergolide	NF-κB	NF-κB
	Ergolide, 源自Inula Britannica干燥花朵提取的倍半萜内酯，有效抑制RAW 264.7巨噬细胞中可诱导型一氧化氮合酶(iNOS)和环氧化酶-2(COX-2)的表达，其机制为失活NF-κB。
T4S1540	Myrislignan	Apoptosis; NF-κB	Apoptosis; NF-κB
	Myrislignan 是一种木酚素，从Myristica fragransHoutt 分离得到，具有抗炎作用。它通过抑制NF-kB 信号通路的激活，减轻LPS 诱导的小鼠巨噬细胞炎症反应。
T3S0807	Berbamine	CaMK; NF-κB; Autophagy	Autophagy; Neuroscience; NF-κB
	Berbamine 是从黄柏中提取的一种天然产物，是钙通道阻滞剂，具有抗肿瘤、免疫调节和心血管作用。
TMA0507	Tomatidine	NF-κB; JNK; Autophagy	Autophagy; MAPK; NF-κB
	Tomatidine 通过阻断 NF-κB 和 JNK 信号传导而发挥抗炎作用。它在哺乳动物细胞或秀丽隐杆线虫中激活自噬。
T3S1641	Esculentoside H	TNF; NF-κB; JNK	Apoptosis; MAPK; NF-κB
	Esculentoside H 是一种皂苷，分离自多年生植物 Phytolacca esculent 的根提取物中，具有抗肿瘤作用。它的机制与 TNF 释放能力有关。它能够阻断 JNK1/2和 NF-κB 信号介导的基质金属蛋白酶-9 (MMP-9) 表达，抑制结肠癌细胞迁移。
T3S1707	Dendrophenol Moscatilin	NF-κB	NF-κB
	Dendrophenol (Moscatilin) 是从石斛茎中分离出来的天然产物，可作为 NF-κB 抑制剂。它有抗肿瘤活性。
T3251	Stachydrine Hydrochloride	NF-κB	NF-κB
	Stachydrine hydrochloride 是Herba Leonuri 的主要活性成分，可以抑制NF-κB 信号通路。它可用于心血管疾病的研究，具有抗心肌肥大活性。
T16324	Nimbolide	Apoptosis; NF-κB; CDK	Apoptosis; Cell Cycle/Checkpoint; NF-κB
	Nimbolide 是源自印楝叶和花的一种三萜。它抑制CDK4/CDK6激酶活性。它抑制 NF-κB，Wnt，PI3K-Akt，MAPK 和 JAK-STAT 信号通路。它通过抑制NF-κB 而诱导肿瘤细胞凋亡。
T5795	Suberosin 软木花椒素	Others; NF-κB	NF-κB; Others
	Suberosin 可分离自Plumbago zeylanica 中，通过调节NF-AT 和NF-κB，抑制PHA-诱导的 PBMC 细胞增殖并捕获细胞周期G1过渡到 S 期，具有抗炎和抗血凝的活性。
T4S0800	Demethyleneberberine	P450; NOS; NF-κB; HIF; AMPK	Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; Metabolism; NF-κB; PI3K/Akt/mTOR signaling
	Demethyleneberberine 是从黄连中提取的一种天然产物，是线粒体靶向抗氧化剂。它也可作为AMPK 激活剂，用于非酒精性脂肪性肝病的研究。它通过抑制NF-κB 通路和调节 Th 细胞的平衡来减轻小鼠结肠炎并抑制炎症反应。
TN2008	Okanin	NF-κB; TLR	Immunology/Inflammation; NF-κB
	Okanin 是鬼针草中的一种有效成分，可通过抑制TLR4/NF-κB 信号通路减弱 LPS 诱导的小胶质细胞活化。
T3877	Esculentoside A	NF-κB; COX	Immunology/Inflammation; Neuroscience; NF-κB
	Esculentoside A 是一种三萜皂苷，从商陆根部分离得到。它在具有抗炎活性，对环氧合酶-2 具有选择性抑制活性。它通过抑制NF-κB 和丝裂原活化蛋白激酶信号通路抑制 LPS 诱导的急性肺损伤中的炎症反应。
T6S0119	Dauricine 蝙蝠葛碱	Apoptosis; Others; NF-κB	Apoptosis; NF-κB; Others
	Dauricine 是存在于北豆根粉末中的一种双苯异喹啉生物碱，具有抗炎活性。它通过抑制NF-κB 激活，剂量依赖性地抑制结肠癌细胞的增值和侵袭，并诱导凋亡。
TL0016	Sulforaphene 油菜	Apoptosis; ERK; EGFR; NF-κB	Angiogenesis; Apoptosis; JAK/STAT signaling; MAPK; NF-κB; Tyrosine Kinase/Adaptors
	Sulforaphene 是从萝卜种子中分离出来的天然产物，对鹿茸幼苗的 ED50 约为 2 x 10 -4 M。它通过抑制 EGFR、p-ERK1/2、NF-κB 和其他信号促进癌细胞凋亡并抑制迁移。
T5S2129	Sciadopitysin	TNF; NF-κB	Apoptosis; NF-κB
	Sciadopitysin 是一种双黄酮类化合物，来自银杏叶片中。它通过抑制NF-κB 活化并降低c-Fos 和NFATc1的表达来抑制 RANKL 诱导的破骨细胞生成和骨丢失。
T11060	DMAPT Dimethylamino Parthenolide	NF-κB	NF-κB
	DMAPT (Dimethylamino Parthenolide) 是一种具有口服活性的NF-κB 抑制剂，是一种 Parthenolide (PTL) 的类似物，对原发性急性髓性白血病细胞的LD50值为1.7 μM。具有潜在的抗肿瘤和抗转移作用。
TN1079	Deoxyelephantopin	NF-κB	NF-κB
	Deoxyelephantopin 是来自Elephantopus scaber 的，具有生物活性的天然倍半萜烯内酯，能够抑制NF-κB，MAPK，PI3K/Akt 和β-catenin 信号传导。它可广泛用于癌症方面的研究。
T3913	Saikosaponin D	Estrogen Receptor/ERR; NF-κB; Antibacterial; STAT	Endocrinology/Hormones; JAK/STAT signaling; Microbiology/Virology; NF-κB; Stem Cells
	Saikosaponin D 是一种从柴胡中分离到的三萜皂苷类天然产物，具有抗炎，抗菌，抗肿瘤，抗过敏作用。它抑制 selectin，STAT3和 NF-kB 的活性，活化estrogen receptor-β。
T3893	Forsythoside B 连翘酯苷 B,连翘脂苷B	TNF; NF-κB	Apoptosis; NF-κB
	Forsythoside B 是传统中药植物独一味叶子中分离的一种苯乙醇苷。它可抑制 TNF-alpha，IL-6，IκB，调节 NF-κB。它抑制炎症反应，具有抗氧化和神经保护作用。
T5S1607	Morusin Mulberrochromene,桑辛素	NF-κB; Antibacterial; STAT	JAK/STAT signaling; Microbiology/Virology; NF-κB; Stem Cells
	Morusin (Mulberrochromene) 是从M. australis 分离的去乙烯基化黄酮，可抑制NF-κB 和STAT3的活性，具有抗菌、抗肿瘤、抗氧化等各种生物活性。
T4S1881	Aconine 乌头原碱,Jesaconine	Others; NF-κB	NF-κB; Others
	Aconine (Jesaconine) 是一种退热药，有胃麻醉作用，能够抑制核因子 κB 受体活化剂配体诱导的 NF-κB 激活。
TQ0131	Rocaglamide Rocaglamide A,楝酰胺,Roc-A	HSP; NF-κB; PERK	Apoptosis; Cytoskeletal Signaling; Metabolism; NF-κB
	Rocaglamide (Roc-A) 是从米仔兰中分离出来的一种天然产物，具有抗癌特性，可用于咳嗽，受伤，哮喘和炎症性皮肤病。它是一种有效的选择性热休克因子 1 活化抑制剂，IC50约为 50 nM。它是 T 细胞中 NF-κB 活化的有效抑制剂，还抑制翻译起始因子eIF4A 的功能。
TN1712	Gossypin	NF-κB; S6 Kinase	MAPK; NF-κB; PI3K/Akt/mTOR signaling
	Gossypin 是一种从Hibiscus vitifolius 中分离得到的黄酮，能够抑制NF-κB 和 NF-κB 的调节基因表达。在小鼠原代骨髓细胞和 RAW264.7 细胞中，它也可抑制 RANKL 诱导的破骨细胞形成。它具有抗氧化、抗炎、抗癌、抗衰老、抗糖尿病和保护肝脏的活性。
T5834	Myrcene	Others	Others
	Myrcene 是具有可挥发性的芳香族化合物，对 TNFα 诱导的 NF-κB 具有抑制作用，且具有抗侵袭的能力。
T6S1572	Sauchinone	ERK; p38 MAPK; NF-κB	MAPK; NF-κB
	Sauchinone 是一种从Saururus chinensis 中获得的非对映异构的木脂素。它通过抑制I-κBα磷酸化和p65核易位来抑制 LPS 诱导的 iNOS，TNF-α 和 COX-2 表达。它具有抗炎和抗氧化活性。
T6718	Zingerone Gingerone,Vanillylacetone,姜酮,NSC 15335	NF-κB	NF-κB
	Zingerone (Vanillylacetone) 是一种从生姜中得到的无毒的甲氧基苯酚，具有抗炎、抗糖尿病、抗脂质过敏、抗腹泻、抗痉挛和抗肿瘤等活性。它作为抗有丝分裂剂，能够抑制神经母细胞瘤的生长。它能够缓解氧化应激和炎症，下调 NF-κB 介导的信号通路。
TN1637	Eurycomalactone	Anti-infection; NF-κB	Microbiology/Virology; NF-κB
	Eurycomalactone 是一种NF-κB 抑制剂，IC50=0.5 μM，是一种天然产物。它可抑制蛋白合成，降低 cyclin D1 蛋白水平，但对 TNFα 诱导的 IκBα 降解或 IKKα/β 和 IκBα 的磷酸化水平没有作用。
T3012	Mangiferin Alpizarin,Chinomin,芒果,Hedysarid	Apoptosis; Others; NF-κB; Nrf2	Apoptosis; Immunology/Inflammation; NF-κB; Others
	Mangiferin (Hedysarid) 是一种Nrf2激活剂。它抑制NF-κB 亚基p65和p50的核移位，具有抗氧化、抗糖尿病、抗高尿酸血症、抗病毒、抗癌和抗炎活性。
T2140	Parthenolide (-)-Parthenolide,小白菊内酯	Apoptosis; Mitophagy; NF-κB; HDAC; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; NF-κB
	Parthenolide ((-)-Parthenolide) 是一种从药草短舌匹菊中发现的倍半萜内酯。它抑制NF-κB 活化，有抗炎活性。它还可抑制HDAC1蛋白，但不影响其他I/II 类HDAC。
T6S0840	Engeletin Dihydrokaempferol 3-rhamnoside,黄杞苷	NF-κB; Reductase	Endocrinology/Hormones; Metabolism; NF-κB
	Engeletin (Dihydrokaempferol 3-rhamnoside) 是一种黄酮苷类物质，从hymenaea martiana 中获得，抑制NF-κB 信号通路的激活，具有抗炎、缓解疼痛、消肿、利尿、抗菌等作用。
T5687	WITHAFERIN A 醉茄素 A,醉茄素A	Ferroptosis; NF-κB	Apoptosis; NF-κB
	Withaferin A 是从南非醉茄中分离到的一种甾体内酯，是内皮蛋白 C 受体脱落抑制剂，可以抑制NF-kB 的活性，具有抗炎，抗肿瘤等作用。它是一种新型 NFkappaB 抑制剂，有望成为治疗各种炎症性疾病和癌症的新型抗炎药。
TN1341	8-Deoxygartanin 8-脱氧藤黄苷	Beta Amyloid; NF-κB; Parasite	Microbiology/Virology; Neuroscience; NF-κB
	8-Deoxygartanin 是山竹果中的异戊烯化呫吨酮。它是丁基胆碱酯酶选择性抑制剂，对阿尔茨海默病 (AD) 具有多功能活性，可能是有希望治疗 AD 的化合物。
T6S0781	Phellodendrine 黄柏碱,Phallodendrin	Others; NF-κB; Akt	Cytoskeletal Signaling; NF-κB; Others; PI3K/Akt/mTOR signaling
	Phellodendrine (Phallodendrin) 是异喹啉生物碱，是黄柏皮层中的重要特征成分之一。它具有良好的抗氧化，抗炎作用。它通过调节AKT/NF-κB 途径抵抗 AAPH 诱导的氧化应激。
T3777	Praeruptorin A (+)-Praeruptorin A,白花前胡甲素	CaMK; NF-κB	Neuroscience; NF-κB
	Praeruptorin A ((+)-Praeruptorin A) 是一种白花前胡的主要生物活性成分。它能够抑制 NF-κB 活化，发挥抗炎作用。
T7786	Tryptanthrin	DNA gyrase	DNA Damage/DNA Repair
	Tryptanthrin 是一种口服具有活性的细胞内Leukotriene (LT) biosynthesis 抑制剂。它能够降低大鼠胸膜炎模型中的 LTB4 水平，并抑制人全血中Leukotriene 的形成 (IC50= 10 µM)。
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天然产物

Euphorbia factor L8

Cat.No: TN1635

Target: Others

Euphorbia factor L7b

Cat.No: TN1634

Synonym: 千金子素L7B

Target: Others

Euphorbia factor L7a

Cat.No: TN1633

Target: Others

Euphorbia factor L1

Cat.No: T2S0410

Synonym: Euphorbiasteroid,大戟因子L1,大戟因子 L1

Target: Apoptosis, P-gp

Euphorbia Factor L2

Cat.No: T5798

Synonym: 千金子素L2,euphorbiafactor L2,大戟因子L2

Target: Apoptosis, NF-κB

Deoxy euphorbia factor L1

Cat.No: T125211

Target: Others

α-Factor Mating Pheromone, yeast TFA

Cat.No: T78500

Synonym: Mating Factor α TFA

Target: Others

Euphorbiasteroid

Cat.No: T3220

Synonym: Euphobiasteroid,Euphorbia factor L1,千金子甾醇

Target: Others, AMPK

Cat.No: T1255

Synonym: NSC 180514,妥布霉素,Nebramycin Factor 6,Deoxykanamycin B

Target: ribosome, Antibacterial, Antibiotic

20-O-Acetylingenol-3-angelate

Cat.No: TQ0099

Synonym: 巨大戟醇-3-O-当归酸-20-乙酸酯,Euphorbia factor Pe1

Target: Others

5,15-Diacetyl-3-benzoyllathyrol

Cat.No: T4S2014

Synonym: ，大戟因子L3,二乙酰基苯甲酰基香豌豆醇,5,15-二乙酰基-3-苯甲酰千金子二萜醇；千金二萜醇二乙酰苯甲酰酯,Euphorbia factor L3

Target: Others

Cat.No: T5688

Target: NOS, NF-κB, COX

Cat.No: TN1131

Target: NF-κB, Immunology/Inflammation related

HOMOPLANTAGININ

Cat.No: T4S0217

Target: TNF, NF-κB

Cat.No: T10383

Target: NF-κB

Cat.No: T13686

Target: NF-κB

Cat.No: T4S1540

Target: Apoptosis, NF-κB

Cat.No: T3S0807

Target: CaMK, NF-κB, Autophagy

Cat.No: TMA0507

Target: NF-κB, JNK, Autophagy

Esculentoside H

Cat.No: T3S1641

Target: TNF, NF-κB, JNK

Cat.No: T3S1707

Synonym: Moscatilin

Target: NF-κB

Stachydrine Hydrochloride

Cat.No: T3251

Target: NF-κB

Cat.No: T16324

Target: Apoptosis, NF-κB, CDK

Cat.No: T5795

Synonym: 软木花椒素

Target: Others, NF-κB

Demethyleneberberine

Cat.No: T4S0800

Target: P450, NOS, NF-κB, HIF, AMPK

Cat.No: TN2008

Target: NF-κB, TLR

Esculentoside A

Cat.No: T3877

Target: NF-κB, COX

Cat.No: T6S0119

Synonym: 蝙蝠葛碱

Target: Apoptosis, Others, NF-κB

Cat.No: TL0016

Synonym: 油菜

Target: Apoptosis, ERK, EGFR, NF-κB

Cat.No: T5S2129

Target: TNF, NF-κB

Cat.No: T11060

Synonym: Dimethylamino Parthenolide

Target: NF-κB

Deoxyelephantopin

Cat.No: TN1079

Target: NF-κB

Cat.No: T3913

Target: Estrogen Receptor/ERR, NF-κB, Antibacterial, STAT

Cat.No: T3893

Synonym: 连翘酯苷 B,连翘脂苷B

Target: TNF, NF-κB

Cat.No: T5S1607

Synonym: Mulberrochromene,桑辛素

Target: NF-κB, Antibacterial, STAT

Cat.No: T4S1881

Synonym: 乌头原碱,Jesaconine

Target: Others, NF-κB

Cat.No: TQ0131

Synonym: Rocaglamide A,楝酰胺,Roc-A

Target: HSP, NF-κB, PERK

Cat.No: TN1712

Target: NF-κB, S6 Kinase

Cat.No: T5834

Target: Others

Cat.No: T6S1572

Target: ERK, p38 MAPK, NF-κB

Cat.No: T6718

Synonym: Gingerone,Vanillylacetone,姜酮,NSC 15335

Target: NF-κB

Eurycomalactone

Cat.No: TN1637

Target: Anti-infection, NF-κB

Cat.No: T3012

Synonym: Alpizarin,Chinomin,芒果,Hedysarid

Target: Apoptosis, Others, NF-κB, Nrf2

Cat.No: T2140

Synonym: (-)-Parthenolide,小白菊内酯

Target: Apoptosis, Mitophagy, NF-κB, HDAC, Autophagy

Cat.No: T6S0840

Synonym: Dihydrokaempferol 3-rhamnoside,黄杞苷

Target: NF-κB, Reductase

Cat.No: T5687

Synonym: 醉茄素 A,醉茄素A

Target: Ferroptosis, NF-κB

8-Deoxygartanin

Cat.No: TN1341

Synonym: 8-脱氧藤黄苷

Target: Beta Amyloid, NF-κB, Parasite

Cat.No: T6S0781

Synonym: 黄柏碱,Phallodendrin

Target: Others, NF-κB, Akt

Cat.No: T3777

Synonym: (+)-Praeruptorin A,白花前胡甲素

Target: CaMK, NF-κB

Cat.No: T7786

Target: DNA gyrase

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-05094	Tissue Factor Protein, Cynomolgus, Recombinant (His) coagulation factor III (thromboplastin, tissue ...	Cynomolgus	HEK293 Cells
	Tissue Factor Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.4 kDa and the accession number is XP_005542723.1.
TMPY-02530	Tissue Factor Protein, Human, Recombinant (His) CD142,coagulation factor III (thromboplastin, tissu...	Human	HEK293 Cells
	Tissue Factor Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P13726.
TMPY-01104	Coagulation factor XI/F11 Protein, Human, Recombinant (His) coagulation factor 11,coagulation factor X...	Human	HEK293 Cells
	Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the presence of calcium ions. It is an unusual dimeric protease, with structural features that distinguish it from vitamin K-dependent coagulation proteases. The factor XI is synthesized in the liver as a single polypeptide chain with a molecular weight estimated between 125 ~160 kDa ...
TMPY-01101	Coagulation factor X/F10 Protein, Human, Recombinant (His) FXA,FX,coagulation factor X,coagulation factor<...	Human	Baculovirus Insect Cells
	Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the coagulation cascade and blood clotting, as the first enzyme in the common pathway of thrombus formation. Factor X deficiency is one of the rarest of the inherited coagulation disorders. FX deficiency among the most severe of the rare coagulation defects, typically including hema...
TMPY-01075	Von Willebrand Factor/vWF Protein, Human, Recombinant (His) von Willebrand factor,VWD,F8VWF	Human	CHO Cells
	Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury. From studies it appears that VWF protein uncoils under these circumstances, decelerating passing platelets. VWF protein is deficient or defective in von Willebrand disease (VWD) and is involved in a large number of other diseases, including thrombosis, thrombotic thr...
TMPY-02185	Coagulation factor XIII B/F13B Protein, Human, Recombinant (His) Coagulation factor 13,coagulation factor X...	Human	HEK293 Cells
	Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein which contains 1 Sushi ( CCP / SCR ) domains. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have en...
TMPY-03221	Intrinsic Factor Protein, Human, Recombinant (His) IF,IFMH,gastric intrinsic factor (vitamin B synthes...	Human	HEK293 Cells
	Gastric intrinsic factor, also known as GIF, belongs to the of the cobalamin transport protein family. It is a glycoprotein produced by the parietal cells of the stomach. Gastric intrinsic factor plays a key role in the absorption of vitamin B12 on in the small intestine. Vitamin B12 bounds to haptocorrin after entry into the stomach. The resulting complex enters the duodenum, where pancreatic enzymes digest haptocorrin. In the less acidic environment of the small intestine, B12 can then bind to...
TMPY-02215	Coagulation factor IX/F9 Protein, Human, Recombinant (His) FIX,PTC,Coagulation factor 9,coagulation factor...	Human	HEK293 Cells
	Coagulation factor IX/F9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50 kDa and the accession number is AAB59620.1.
TMPY-04921	Complement factor B/CFB Protein, Human, Recombinant (His) ARMD14,GBG,AHUS4,PBF2,complement factor B,FBI12,BF,...	Human	HEK293 Cells
	Complement factor B/CFB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.5 kDa and the accession number is AAH04143.1.
TMPK-00993	Coagulation Factor III/Tissue Factor Protein, Canine, Recombinant (His) Thromboplastin,CD142,TF,FLJ17960,TFA,F3,Coagulation Fact...	Canine	HEK293 Cells
	Tissue factor (also named Coagulation Factor III) is a cell surface glycoprotein responsible for initiating the extrinsic pathway of coagulation.Tissue factor is the primary cellular initiator of blood coagulation via interaction with coagulation factor VII. Aberrant expression of tissue factor is responsible for thrombosis during septic shock, atherosclerosis and cancer.
TMPY-02318	Tissue Factor Protein, Rabbit, Recombinant (His) coagulation factor III (thromboplastin, tissue ...	Rabbit	HEK293 Cells
	Tissue Factor Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.4 kDa and the accession number is P24055.
TMPY-02537	Tissue Factor Protein, Human, Recombinant (hFc) coagulation factor III,coagulation factor ...	Human	HEK293 Cells
	Tissue Factor Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.8 kDa and the accession number is P13726.
TMPJ-00301	Coagulation Factor X Protein, Human, Recombinant (hFc) Stuart-Prower factor,Stuart factor,Coagula...	Human	HEK293 Cells
	F10, also known as Coagulation factor X, belongs to the peptidase S1 family that is synthesized as a 488 amino acid (aa) with a signal peptide and a pro region (residues 1‑40). Both the intrinsic and extrinsic pathways activate Factor X to Xa, which consists of light (residues 41‑179) and heavy (residues 235‑488) chains linked by a disulfide bond. Coagulation factor X is initially synthesized in the liver. The two chains are formed from a single-chain precursor by the excision of two Arg residue...
TMPY-03209	Tissue Factor Protein, Rat, Recombinant (His) coagulation factor III (thromboplastin, tissue ...	Rat	HEK293 Cells
	Tissue Factor Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.2 kDa and the accession number is Q66HI4.
TMPH-03106	Coagulation factor XII Protein, Pig, Recombinant (His) HAF,Hageman factor,F12,Coagulation factor ...	Sus scrofa (Pig)	E. coli
	Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa. Coagulation factor XII Protein, Pig, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predic...
TMPY-01325	Tissue Factor Protein, Mouse, Recombinant (His) Cf-3,AA409063,CD142,coagulation factor III (thrombo...	Mouse	HEK293 Cells
	Tissue Factor Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is A0A0R4J088.
TMPY-06957	Tissue Factor Protein, Human, Recombinant (hFc & Avi), Biotinylated TFA,coagulation factor 3,coagulation factor	Human	HEK293 Cells
	Tissue Factor Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 53.34 kDa and the accession number is P13726.
TMPJ-00707	Coagulation factor X/F10 Protein, Mouse, Recombinant (His) Stuart factor,Coagulation factor X,F10	Mouse	HEK293 Cells
	Mouse coagulation factor X / F10 a member of the peptidase S1 family. The mature F10 is composed mostly of two EGF-like domains, one Gla gamma-carboxy-glutamate domain and one peptidase S1 domain. Factor Xa is a vitamin K-dependent plasma protease that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting. The two chains of F10 are formed from a single-chain precursor by the excision of two Arg residues. A single-chain precursor is initiall...
TMPY-04996	Coagulation Factor II Protein, Rat, Recombinant (His) coagulation factor II (thrombin)	Rat	HEK293 Cells
	Coagulation Factor II Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.5 kDa and the accession number is A6HND0.
TMPJ-00166	SCF Protein, Mouse, Recombinant SCF,Hematopoietic growth factor KL,MGF,Steel fa...	Mouse	E. coli
	Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. It also promotes phosphorylation of PIK3R1, which is the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the ...
TMPY-02183	Complement Factor D/CFD Protein, Human, Recombinant (His) PFD,DF,complement factor D (adipsin),ADN,FACTOR...	Human	HEK293 Cells
	Complement Factor D/CFD Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.8 kDa and the accession number is P00746.
TMPY-05083	Tissue Factor Protein, Human, Recombinant (aa 1-295, His) coagulation factor 3,TF,TFA,coagulation factor<...	Human	Baculovirus Insect Cells
	Tissue Factor Protein, Human, Recombinant (aa 1-295, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 31 kDa and the accession number is P13726-1.
TMPY-02014	Coagulation factor VII/F7 Protein, Human, Recombinant (His) coagulation factor VII (serum prothrombin conversio...	Human	HEK293 Cells
	Coagulation factor VII, also known as Serum prothrombin conversion accelerator, Factor VII, F7 and FVII, is a member of the peptidase S1 family. Factor VII is one of the central proteins in the coagulation cascade. It is an enzyme of the serine protease class, and Factor VII (FVII) deficiency is the most frequent among rare congenital bleeding disorders. Factor VII contains two EGF-like domains, one Gla (gamma-carboxy-glutamate) domain and one peptidase S1 domain. The main role of factor VII is ...
TMPK-01271	Coagulation factor XI Protein, Cynomolgus, Recombinant (His) F11,PTA,FXI,Coagulation factor XI	Cynomolgus	HEK293 Cells
	Factor XI (FXI) is the zymogen of a plasma protease (FXIa) that contributes to hemostasis by activating factor IX (FIX). In the original cascade model of coagulation, FXI is converted to FXIa by factor XIIa (FXIIa), a component, along with prekallikrein and high-molecular-weight kininogen (HK), of the plasma kallikrein-kinin system (KKS).
TMPY-06714	Coagulation factor IX/F9 Protein, Cynomolgus, Recombinant (His) coagulation factor IX	Cynomolgus	HEK293 Cells
	Coagulation factor IX/F9 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.17 kDa and the accession number is A0A8J8XCV8.
TMPH-01107	Coagulation factor V Protein, Human, Recombinant (His & SUMO) F5,Activated protein C cofactor,Coagulation fac...	Human	E. coli
	Coagulation factor V Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-03618	Clotting factor C Protein, Tachypleus tridentatus, Recombinant (His & Myc) FC,Limulus factor C,Clotting factor C	Tachypleus tridentatus	E. coli
	This enzyme is closely associated with an endotoxin-sensitive hemolymph coagulation system which may play important roles in both hemostasis and host defense mechanisms. Its active form catalyzes the activation of clotting factor B. Clotting factor C Protein, Tachypleus tridentatus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.8 kDa and the accession number is P28175.
TMPH-03272	Complement factor D Protein, Rat, Recombinant (His) Adipsin,Df,Adn,C3 convertase activator,Complement factor...	Rat	P. pastoris (Yeast)
	Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
TMPH-03268	Coagulation factor XI Protein, Rat, Recombinant (His & Myc) Coagulation factor XI,F11	Rat	E. coli
	Coagulation factor XI Protein, Rat, Recombinant (His & Myc) is expressed in E. coli.
TMPY-01791	Coagulation Factor II Protein, Mouse, Recombinant (His) Cf-2,coagulation factor II (thrombin),Cf2,FII	Mouse	HEK293 Cells
	Coagulation Factor II Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.3 kDa and the accession number is P19221.
TMPY-05355	Coagulation factor IX/F9 Protein, Human, Recombinant (hFc) P19,Coagulation factor 9,HEMB,FIX,THPH8,Coagulation...	Human	HEK293 Cells
	Coagulation factor IX/F9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 75.5 kDa and the accession number is P00740-1.
TMPY-02342	MIF Protein, Mouse, Recombinant GIF,macrophage migration inhibitory factor (glycosy...	Mouse	E. coli
	MIF Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 12.5 kDa and the accession number is P34884.
TMPH-00020	Elongation factor Tu Protein, Acinetobacter baumannii, Recombinant (His) Elongation factor Tu,EF-Tu	Acinetobacter baumannii	P. pastoris (Yeast)
	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
TMPJ-00149	Complement Factor D/CFD Protein, Mouse, Recombinant (His) C3 convertase activator,28 kDa adipocyte protein,Cfd,Adipsin...	Mouse	HEK293 Cells
	Complement factor D, also known as adipsin, is a member of the chymotrypsin family of serine proteases, which plays an essential role in host defense as the rate-limiting enzyme in the alternative pathway of complement activation. Complement factor D activates a convertase (C3bBb) responsible for cleavage of the complement protein C3, which leads to the activation of terminal complement component C5-9 to form the membrane attack complex on microbial or cellular surfaces. It also functions in the...
TMPH-00346	Limulus clotting factor C Protein, Carcinoscorpius rotundicauda, Recombinant (His) Limulus clotting factor C	Carcinoscorpius rotundicauda	E. coli
	This enzyme is closely associated with an endotoxin-sensitive hemolymph coagulation system which may play important roles in both hemostasis and host defense mechanisms. Its active form catalyzes the activation of factor B. Limulus clotting factor C Protein, Carcinoscorpius rotundicauda, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 42.2 kDa and the accession number is Q26422.
TMPH-02974	Von Willebrand Factor/vWF Protein, Mouse, Recombinant (His & Myc) Vwf,von Willebrand factor	Mouse	E. coli
	Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma. Von Willebrand Factor/vWF Protein, Mouse, Recombinant (His & Myc) is expressed in E....
TMPY-00117	FGF-16 Protein, Human, Cynomolgus, Recombinant fibroblast growth factor 16	Human,Cynomolgus	Baculovirus Insect Cells
	Fibroblast growth factor 16 (FGF16) is preferentially expressed in the heart after birth, suggesting its regulation is associated with tissue-specific chromatin remodeling and DNA-protein interactions. Mutation of the MEF2 site resulted in a blunting of FGF16 promoter activity in transfected neonatal rat cardiac myocytes, that chromatin remodeling and MEF2 binding in the FGF16 promoter contribute to expression in the postnatal heart. FGF16 involvement in the fine tuning of the human skeleton of ...
TMPY-01864	CNTF Protein, Human, Recombinant (His) ciliary neurotrophic factor,HCNTF	Human	E. coli
	CNTF Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 24.5 kDa and the accession number is P26441.
TMPH-03271	Complement factor D Protein, Rat, Recombinant (His & Myc) Adn,C3 convertase activator,Properdin factor D,Comp...	Rat	HEK293 Cells
	Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. Complement factor D Protein, Rat, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 29.8 kDa and the accession number is P32038.
TMPY-04129	Complement factor H/CFH Protein, Mouse, Recombinant (His) Sas-1,Mud-1,NOM,complement factor H,Sas1	Mouse	HEK293 Cells
	Complement factor H/CFH Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.8 kDa and the accession number is E9Q8I0.
TMPY-04141	Complement factor H/CFH Protein, Mouse, Recombinant (hFc) complement factor H,Sas1,NOM,Mud-1,Sas-1	Mouse	HEK293 Cells
	Complement factor H/CFH Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 69.1 kDa and the accession number is E9Q8I0.
TMPK-00755	Complement Factor D/CFD Protein, Human, Recombinant (hFc) C3 convertase activator,DF,AMBP-1,EC 3.4.21,EC 3.4.21.46,Adi...	Human	HEK293 Cells
	Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Human, Recom...
TMPK-01023	Complement factor I Protein, Mouse, Recombinant (His) FIC3b-INA,I factor (complement),IF,C3B/C4B inactiva...	Mouse	HEK293 Cells
	Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 66.39 kDa and the accession number is Q61129.
TMPY-05510	BDNF Protein, Mouse, Recombinant (His) brain-derived neurotrophic factor	Mouse	HEK293 Cells
	BDNF is a member of thenerve growth factorfamily. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. It participates in axonal growth,...
TMPY-02167	Complement Factor D/CFD Protein, Mouse, Recombinant (His,HEK293) DF,Adn,complement factor D (adipsin)	Mouse	HEK293 Cells
	Complement Factor D/CFD Protein, Mouse, Recombinant (His,HEK293) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa and the accession number is P03953-2.
TMPY-04818	EGFR Protein, Cynomolgus, Recombinant (His) epidermal growth factor receptor	Cynomolgus	HEK293 Cells
	EGFR Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.1 kDa and the accession number is A0A2K5WK39.
TMPK-00790	Complement factor H/CFH Protein, Human, Recombinant (His) ARMD4,AHUS1,H factor 1,HF1,AMBP1,FH,FHL1,HUS,CFHL3,...	Human	HEK293 Cells
	Factor H is the major soluble inhibitor of complement, where its binding to self markers (i.e., particular glycan structures) prevents complement activation and amplification on host surfaces. Not surprisingly, mutations and polymorphisms that affect recognition of self by factor H are associated with diseases of complement dysregulation, such as age-related macular degeneration and atypical haemolytic uremic syndrome. In addition, pathogens (i.e., non-self) and cancer cells (i.e., altered-self)...
TMPH-01108	Factor VII Protein, Human, Recombinant (His & SUMO) F7,Serum prothrombin conversion accelerator,Proconvertin,Coa...	Human	E. coli
	Factor VII Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-03273	Complement factor I Protein, Rat, Recombinant (His & Myc) If,Complement factor I,Cfi,C3B/C4B inactivator	Rat	Baculovirus Insect Cells
	Complement factor I Protein, Rat, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 69.2 kDa and the accession number is Q9WUW3.
TMPK-00151	Complement Factor D/CFD Protein, Mouse, Recombinant (hFc) C3 convertase activator,AMBP-1,PFD,FACTOR D,CFD,ADN...	Mouse	HEK293 Cells
	Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Mouse, Recom...
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重组蛋白

Tissue Factor Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-05094

Species: Cynomolgus

Expression System: HEK293 Cells

Tissue Factor Protein, Human, Recombinant (His)

Cat.No: TMPY-02530

Species: Human

Expression System: HEK293 Cells

Coagulation factor XI/F11 Protein, Human, Recombinant (His)

Cat.No: TMPY-01104

Species: Human

Expression System: HEK293 Cells

Coagulation factor X/F10 Protein, Human, Recombinant (His)

Cat.No: TMPY-01101

Species: Human

Expression System: Baculovirus Insect Cells

Von Willebrand Factor/vWF Protein, Human, Recombinant (His)

Cat.No: TMPY-01075

Species: Human

Expression System: CHO Cells

Coagulation factor XIII B/F13B Protein, Human, Recombinant (His)

Cat.No: TMPY-02185

Species: Human

Expression System: HEK293 Cells

Intrinsic Factor Protein, Human, Recombinant (His)

Cat.No: TMPY-03221

Species: Human

Expression System: HEK293 Cells

Coagulation factor IX/F9 Protein, Human, Recombinant (His)

Cat.No: TMPY-02215

Species: Human

Expression System: HEK293 Cells

Complement factor B/CFB Protein, Human, Recombinant (His)

Cat.No: TMPY-04921

Species: Human

Expression System: HEK293 Cells

Coagulation Factor III/Tissue Factor Protein, Canine, Recombinant (His)

Cat.No: TMPK-00993

Species: Canine

Expression System: HEK293 Cells

Tissue Factor Protein, Rabbit, Recombinant (His)

Cat.No: TMPY-02318

Species: Rabbit

Expression System: HEK293 Cells

Tissue Factor Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02537

Species: Human

Expression System: HEK293 Cells

Coagulation Factor X Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00301

Species: Human

Expression System: HEK293 Cells

Tissue Factor Protein, Rat, Recombinant (His)

Cat.No: TMPY-03209

Species: Rat

Expression System: HEK293 Cells

Coagulation factor XII Protein, Pig, Recombinant (His)

Cat.No: TMPH-03106

Species: Sus scrofa (Pig)

Expression System: E. coli

Tissue Factor Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01325

Species: Mouse

Expression System: HEK293 Cells

Tissue Factor Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPY-06957

Species: Human

Expression System: HEK293 Cells

Coagulation factor X/F10 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00707

Species: Mouse

Expression System: HEK293 Cells

Coagulation Factor II Protein, Rat, Recombinant (His)

Cat.No: TMPY-04996

Species: Rat

Expression System: HEK293 Cells

SCF Protein, Mouse, Recombinant

Cat.No: TMPJ-00166

Species: Mouse

Expression System: E. coli

Complement Factor D/CFD Protein, Human, Recombinant (His)

Cat.No: TMPY-02183

Species: Human

Expression System: HEK293 Cells

Tissue Factor Protein, Human, Recombinant (aa 1-295, His)

Cat.No: TMPY-05083

Species: Human

Expression System: Baculovirus Insect Cells

Coagulation factor VII/F7 Protein, Human, Recombinant (His)

Cat.No: TMPY-02014

Species: Human

Expression System: HEK293 Cells

Coagulation factor XI Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01271

Species: Cynomolgus

Expression System: HEK293 Cells

Coagulation factor IX/F9 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-06714

Species: Cynomolgus

Expression System: HEK293 Cells

Coagulation factor V Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01107

Species: Human

Expression System: E. coli

Clotting factor C Protein, Tachypleus tridentatus, Recombinant (His & Myc)

Cat.No: TMPH-03618

Species: Tachypleus tridentatus

Expression System: E. coli

Complement factor D Protein, Rat, Recombinant (His)

Cat.No: TMPH-03272

Species: Rat

Expression System: P. pastoris (Yeast)

Coagulation factor XI Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03268

Species: Rat

Expression System: E. coli

Coagulation Factor II Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01791

Species: Mouse

Expression System: HEK293 Cells

Coagulation factor IX/F9 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05355

Species: Human

Expression System: HEK293 Cells

MIF Protein, Mouse, Recombinant

Cat.No: TMPY-02342

Species: Mouse

Expression System: E. coli

Elongation factor Tu Protein, Acinetobacter baumannii, Recombinant (His)

Cat.No: TMPH-00020

Species: Acinetobacter baumannii

Expression System: P. pastoris (Yeast)

Complement Factor D/CFD Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00149

Species: Mouse

Expression System: HEK293 Cells

Limulus clotting factor C Protein, Carcinoscorpius rotundicauda, Recombinant (His)

Cat.No: TMPH-00346

Species: Carcinoscorpius rotundicauda

Expression System: E. coli

Von Willebrand Factor/vWF Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02974

Species: Mouse

Expression System: E. coli

FGF-16 Protein, Human, Cynomolgus, Recombinant

Cat.No: TMPY-00117

Species: Human,Cynomolgus

Expression System: Baculovirus Insect Cells

CNTF Protein, Human, Recombinant (His)

Cat.No: TMPY-01864

Species: Human

Expression System: E. coli

Complement factor D Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03271

Species: Rat

Expression System: HEK293 Cells

Complement factor H/CFH Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04129

Species: Mouse

Expression System: HEK293 Cells

Complement factor H/CFH Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-04141

Species: Mouse

Expression System: HEK293 Cells

Complement Factor D/CFD Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00755

Species: Human

Expression System: HEK293 Cells

Complement factor I Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01023

Species: Mouse

Expression System: HEK293 Cells

BDNF Protein, Mouse, Recombinant (His)

Cat.No: TMPY-05510

Species: Mouse

Expression System: HEK293 Cells

Complement Factor D/CFD Protein, Mouse, Recombinant (His,HEK293)

Cat.No: TMPY-02167

Species: Mouse

Expression System: HEK293 Cells

EGFR Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-04818

Species: Cynomolgus

Expression System: HEK293 Cells

Complement factor H/CFH Protein, Human, Recombinant (His)

Cat.No: TMPK-00790

Species: Human

Expression System: HEK293 Cells

Factor VII Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01108

Species: Human

Expression System: E. coli

Complement factor I Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03273

Species: Rat

Expression System: Baculovirus Insect Cells

Complement Factor D/CFD Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00151

Species: Mouse

Expression System: HEK293 Cells

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Cat. No.	Product Name	Target	Signaling Pathways
T10349	Apixaban 13C,d3 Apixaban 13CD3,BMS-562247-01 13CD3	Others	Others
	Apixaban 13CD3 (BMS-562247-01 13CD3) is a deuterium-labeled Apixaban. Apixaban is a reversible inhibitor of Factor Xa (Ki: 0.08 nM and 0.17 nM in human and rabbit).
T12736	Rivaroxaban-d4 BAY 59-7939 D4	Factor Xa	Metabolism
	Rivaroxaban D4 is a deuterium labeled Rivaroxaban. Rivaroxaban is a highly potent,selective and direct inhibitor of Factor Xa (FXa)(IC50:0.7 nM; Ki:0.4 nM).
TMIJ-0132	Edoxaban-d6
	Edoxaban-d6 是 Edoxaban 的氘代化合物。Edoxaban 的 CAS 号为 480449-70-5。Edoxaban 是一种口服 Xa 因子 (FXa) 抑制剂，用于中风预防的临床开发。
TMID-0021	Fruquintinib-d3
	Fruquintinib-d3 是 Fruquintinib 的氘代化合物。Fruquintinib 的 CAS 号为 1194506-26-7。Fruquintinib 是一种选择性的VEGFR 1/2/3抑制剂，它们的IC50值分别为33 nM、0.5 nM、35 nM。
TMID-0121	DL-Homocysteine-3,3,4,4-d4
	DL-Homocysteine-3,3,4,4-d4 是 DL-Homocysteine 的氘代化合物。DL-Homocysteine 的 CAS 号为 454-29-5。DL-Homocysteine 是弱神经毒素，能够影响犬尿酸的产生。
TMIH-0591	Vadadustat-13C2-15N
	Vadadustat-13C2-15N 是 Vadadustat 的 13C 和 15N 的标记化合物。Vadadustat 的 CAS 号为 1000025-07-9。Vadadustat 是一种可滴定口服的缺氧诱导因子脯氨酰羟化酶 (HIF-PH) 抑制剂，是一种促红细胞生成剂，在动物慢性肾脏疾病模型中，有用于贫血的研究潜力。
TMIH-0281	Indobufen-d5
	Indobufen-d5 是 Indobufen 的氘代化合物。Indobufen 的 CAS 号为 63610-08-2。Indobufen 是一种血小板聚集抑制剂，是下调单核细胞中的组织因子，可逆抑制血小板环氧合酶 (Cox) 的活性和血栓素 A2 (TxA2) 的合成。
TMIH-0278	Iguratimod-d5
	Iguratimod-d5 是 Iguratimod 的氘代化合物。Iguratimod 的 CAS 号为 123663-49-0。Iguratimod 是一种抗风湿药，作为 COX-2 的抑制剂，IC50 为 20 μM (7.7 μg/mL)。它还抑制巨噬细胞迁移抑制因子 (MIF)，IC50值为 6.81 μM。
TMIH-0124	Brivanib Alaninate-d4
	Brivanib Alaninate-d4 是 Brivanib Alaninate 的氘代化合物。Brivanib Alaninate 的 CAS 号为 649735-63-7。Brivanib alaninate 是一种血管内皮生长因子受体 2 (VEGFR2) 抑制剂的丙氨酸盐，IC50值为 25 nM，具有潜在的抗肿瘤活性。它对 VEGFR1 和 FGFR1 适度抑制，对 VEGFR2 的选择性是对 PDGFRβ 的 240 倍。
T67921	Retinoic acid-d5 all-trans-Retinoic acid-d5,Isotretinoin-d5,Vitamin A acid-d5,Accutane-d5,ATRA-d5	Retinoid Receptor	Metabolism
	Retinoic acid-d5 (Vitamin A acid-d5)是视黄酸的氘标记形式。视黄酸是一种天然的RAR 核受体激动剂，对 RARα/β/γ 的 IC50 为 14 nM，与 PPARβ/δ 结合的Kd 为 17 nM。视黄酸是维生素a 的代谢物，在细胞生长、分化和器官发育中起着重要作用。视黄酸通过激活视黄酸受体α作为转录因子Nrf2的抑制剂来发挥作用。
T71293	Nifuroxazide-d4
	Nifuroxazide-d4 is intended for use as an internal standard for the quantification of nifuroxazide by GC- or LC-MS. Nifuroxazide is a nitrofuran antibiotic. It is active against strains of the enteropathogenic bacteria C. jejuni, Salmonella, Y. enterocolitica, Shigella, and E. coli. It inhibits quorum sensing and virulence factor production in P. aeruginosa. Nifuroxazide inhibits STAT3 activity in a reporter assay and decreases viability of U266 and INA-6 myeloma cells, which have constitutive S...
T69966	Roxadustat-d5
	Roxadustat-d5 is intended for use as an internal standard for the quantification of roxadustat by GC- or LC-MS. Roxadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH; IC50s = 1.4, 1.26, and 1.32 µM for HIF-PH1, HIF-PH2, and HIF-PH3, respectively). It is selective for HIF-PH over other 2-oxoglutarate-dependent dioxygenases, including lysine-specific demethylase 5A (KDM5A), KDM5B, -5C, -5D, and -6B (IC50s = >100 µM for all). Roxadustat (10-200 µM) stabilizes HIF-1α and ...
T70882	Orlistat-d3
	Orlistat-d3 is intended for use as an internal standard for the quantification of orlistat by GC- or LC-MS. Orlistat is a digestive lipase inhibitor. It inhibits diacylglycerol lipase α (DAGLα), DAGLβ, α/β-hydrolase domain-containing protein 12 (ABHD12), ABHD16A, and platelet-activating factor acetylhydrolase (PAF-AH; IC50s = 0.06, 0.1, 0.08, 0.03, and 0.05 µM, respectively), as well as pancreatic lipase and hormone-sensitive lipase (IC50s = 0.65 and 2.1 µg/ml, respectively) but does not inhibit...
TMID-0254	Linalool-d3
	Linalool-d3 是 Linalool 的氘代化合物。Linalool 的 CAS 号为 78-70-6。Linalool 是存在芫荽等植物中的单萜类天然产物，是竞争性NMDA受体拮抗剂，具有抗肿瘤和抗心脏毒性的作用。它通过激活 Nrf2 诱导抗氧化防御和通过抑制 NF-κB 减少炎症反应来保护其免受 LPS/GalN 诱导的肝损伤，具有镇痛、抗菌和抗炎的特性。
T36383	L-Thyroxine-13C9,15N L-Thyroxine-13C9,15N
	L-Thyroxine-13C9,15N is intended for use as an internal standard for the quantification of L-thyroxine by GC- or LC-MS. L-Thyroxine is a synthetic form of the thyroid hormone thyroxine. In vivo, L-thyroxine (0.9 and 2.7 μg) inhibits synthesis and release of thyrotropin induced by thyrotropin-releasing hormone from the anterior pituitary in mice. It also reverses decreases in levels of circulating thymic serum factor (FTS) and the number of T rosette-forming cells in an old age-induced mouse mode...
T35915	Erlotinib-13C6 Erlotinib-13C6
	Erlotinib-13C6 (CP-358774-13C6) is a 13C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1]. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer[1].Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process[2]...

同位素标记化合物

Apixaban 13C,d3

Cat.No: T10349

Synonym: Apixaban 13CD3,BMS-562247-01 13CD3

Target: Others

Cat.No: T12736

Synonym: BAY 59-7939 D4

Target: Factor Xa

Cat.No: TMIJ-0132

Fruquintinib-d3

Cat.No: TMID-0021

DL-Homocysteine-3,3,4,4-d4

Cat.No: TMID-0121

Vadadustat-13C2-15N

Cat.No: TMIH-0591

Cat.No: TMIH-0281

Cat.No: TMIH-0278

Brivanib Alaninate-d4

Cat.No: TMIH-0124

Retinoic acid-d5

Cat.No: T67921

Synonym: all-trans-Retinoic acid-d5,Isotretinoin-d5,Vitamin A acid-d5,Accutane-d5,ATRA-d5

Target: Retinoid Receptor

Nifuroxazide-d4

Cat.No: T71293

Cat.No: T69966

Cat.No: T70882

Cat.No: TMID-0254

L-Thyroxine-13C9,15N

Cat.No: T36383

Synonym: L-Thyroxine-13C9,15N

Cat.No: T35915

Synonym: Erlotinib-13C6

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