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Anti-IL11 Monoclonal Antibody

产品编号 TMAZ-0001
别名 Adipogenesis inhibitory factor, Interleukin-11

Anti-IL11 Monoclonal Antibody is a rabbit antibody targeting IL11. Anti-IL11 Monoclonal Antibody can be used in ELISA, FACS.

Anti-IL11 Monoclonal Antibody

Anti-IL11 Monoclonal Antibody

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产品编号 TMAZ-0001 别名 Adipogenesis inhibitory factor, Interleukin-11

Anti-IL11 Monoclonal Antibody is a rabbit antibody targeting IL11. Anti-IL11 Monoclonal Antibody can be used in ELISA, FACS.

规格价格库存数量
25 μg¥ 1,063.72¥ 1,8347日内发货
50 μg¥ 1,276¥ 2,2007日内发货
100 μg¥ 1,785.82¥ 3,0797日内发货
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产品介绍

生物活性
产品描述
Anti-IL11 Monoclonal Antibody is a rabbit antibody targeting IL11. Anti-IL11 Monoclonal Antibody can be used in ELISA, FACS.
别名Adipogenesis inhibitory factor, Interleukin-11
Ig Type
Rabbit monoclonal IgG
交叉反应
Human
验证活性
Flow cytometry analysis of IL11 overexpressed 437F cells with TMAZ-0001, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
应用
ELISA, FACS
推荐剂量
0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位GPI-anchor
构建方式This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of IL11 protein.
纯化方式Protein A Affinity Purified
性状Liquid
缓冲液0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin.
纯度> 95% as determined by SDS-PAGE.
研究背景Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed: 2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and IL11RA activates a signaling cascade that promotes cell proliferation (PubMed: 12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. The interaction with the membrane-bound IL11RA and IL6ST stimulates 'classic signaling', whereas the binding of IL11 and soluble IL11RA to IL6ST stimulates 'trans-signaling' (PubMed: 30279168)
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Biotin/APC/PE/AF488/AF555/AF647
可提供抗体种类
2
抗原信息
免疫原
IL11
抗原种属
Human
基因ID
3589
Uniprot ID
研究领域
Immunology Research
化学信息
分子量150 kDa
存储&运输
储存方式For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze.
运输方式Shipping with blue ice.

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