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Anti-IL11 Monoclonal Antibody
产品编号 TMAZ-0001
别名 Adipogenesis inhibitory factor, Interleukin-11
Anti-IL11 Monoclonal Antibody is a rabbit antibody targeting IL11. Anti-IL11 Monoclonal Antibody can be used in ELISA, FACS.
Anti-IL11 Monoclonal Antibody
Anti-IL11 Monoclonal Antibody
产品编号 TMAZ-0001 别名 Adipogenesis inhibitory factor, Interleukin-11
Anti-IL11 Monoclonal Antibody is a rabbit antibody targeting IL11. Anti-IL11 Monoclonal Antibody can be used in ELISA, FACS.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μg | ¥ 1,063.72¥ 1,834 | 7日内发货 | |
| 50 μg | ¥ 1,276¥ 2,200 | 7日内发货 | |
| 100 μg | ¥ 1,785.82¥ 3,079 | 7日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
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| 产品描述 | Anti-IL11 Monoclonal Antibody is a rabbit antibody targeting IL11. Anti-IL11 Monoclonal Antibody can be used in ELISA, FACS. |
| 别名 | Adipogenesis inhibitory factor, Interleukin-11 |
| Ig Type | Rabbit monoclonal IgG |
| 交叉反应 | Human |
| 验证活性 | Flow cytometry analysis of IL11 overexpressed 437F cells with TMAZ-0001, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| 应用 | ELISA, FACS |
| 推荐剂量 | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | GPI-anchor |
| 构建方式 | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of IL11 protein. |
| 纯化方式 | Protein A Affinity Purified |
| 性状 | Liquid |
| 缓冲液 | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| 纯度 | > 95% as determined by SDS-PAGE. |
| 研究背景 | Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed: 2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and IL11RA activates a signaling cascade that promotes cell proliferation (PubMed: 12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. The interaction with the membrane-bound IL11RA and IL6ST stimulates 'classic signaling', whereas the binding of IL11 and soluble IL11RA to IL6ST stimulates 'trans-signaling' (PubMed: 30279168) |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Biotin/APC/PE/AF488/AF555/AF647 |
| 可提供抗体种类 | 2 |
| 免疫原 | IL11 |
| 抗原种属 | Human |
| 基因ID | 3589 |
| Uniprot ID | |
| 研究领域 | Immunology Research |
| 分子量 | 150 kDa |
存储&运输
| 储存方式 | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| 运输方式 | Shipping with blue ice. |
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