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Anti-F2 Monoclonal Antibody
产品编号 TMAZ-0378
别名 Coagulation factor II, Prothrombin
Anti-F2 Monoclonal Antibody is an unconjugated rabbit antibody targeting F2. Anti-F2 Monoclonal Antibody can be used in ELISA, FACS.
Anti-F2 Monoclonal Antibody
Anti-F2 Monoclonal Antibody
产品编号 TMAZ-0378 别名 Coagulation factor II, Prothrombin
Anti-F2 Monoclonal Antibody is an unconjugated rabbit antibody targeting F2. Anti-F2 Monoclonal Antibody can be used in ELISA, FACS.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μg | ¥ 725¥ 1,250 | 7日内发货 | |
| 50 μg | ¥ 870¥ 1,500 | 7日内发货 | |
| 100 μg | ¥ 1,217.42¥ 2,099 | 7日内发货 |
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生物活性
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抗原信息
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| 产品描述 | Anti-F2 Monoclonal Antibody is an unconjugated rabbit antibody targeting F2. Anti-F2 Monoclonal Antibody can be used in ELISA, FACS. |
| 别名 | Coagulation factor II, Prothrombin |
| Ig Type | Rabbit monoclonal IgG |
| 交叉反应 | Human |
| 验证活性 | Flow cytometry analysis of F2 overexpressed 448F cells with TMAZ-0378, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| 应用 | ELISA, FACS |
| 推荐剂量 | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted |
| 构建方式 | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of F2 protein. |
| 纯化方式 | Protein A Affinity Purified |
| 性状 | Liquid |
| 纯度 | > 95% as determined by SDS-PAGE. |
| 研究背景 | Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing. Thrombin triggers the production of pro-inflammatory cytokines, such as MCP-1/CCL2 and IL8/CXCL8, in endothelial cells (PubMed:30568593, PubMed:9780208) |
| 其他可选修饰符 | Biotin/APC/PE/AF488/AF555/AF647 |
| 可提供抗体种类 | 1 |
| 免疫原 | F2 |
| 抗原种属 | Human |
| 基因ID | 2147 |
| Uniprot ID | |
| 研究领域 | Drug Target |
| 分子量 | 150 kDa |
存储&运输
| 储存方式 | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| 运输方式 | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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