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Anti-KITLG Monoclonal Antibody
产品编号 TMAZ-0211
别名 Mast cell growth factor, Kit ligand, c-Kit ligand, Stem cell factor
Anti-KITLG Monoclonal Antibody is a rabbit antibody targeting KITLG. Anti-KITLG Monoclonal Antibody can be used in ELISA, FACS, IF.
Anti-KITLG Monoclonal Antibody
Anti-KITLG Monoclonal Antibody
产品编号 TMAZ-0211 别名 Mast cell growth factor, Kit ligand, c-Kit ligand, Stem cell factor
Anti-KITLG Monoclonal Antibody is a rabbit antibody targeting KITLG. Anti-KITLG Monoclonal Antibody can be used in ELISA, FACS, IF.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μg | ¥ 488.36¥ 842 | 7日内发货 | |
| 50 μg | ¥ 585.8¥ 1,010 | 7日内发货 | |
| 100 μg | ¥ 820.12¥ 1,414 | 7日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
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| 产品描述 | Anti-KITLG Monoclonal Antibody is a rabbit antibody targeting KITLG. Anti-KITLG Monoclonal Antibody can be used in ELISA, FACS, IF. |
| 别名 | Mast cell growth factor, Kit ligand, c-Kit ligand, Stem cell factor |
| Ig Type | Rabbit monoclonal IgG |
| 交叉反应 | Human |
| 验证活性 | Flow cytometry analysis of KITLG overexpressed 427F cells with TMAZ-0211, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| 应用 | ELISA, FACS, IF |
| 推荐剂量 | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Single-pass type I membrane |
| 构建方式 | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of KITLG protein. |
| 纯化方式 | Protein A Affinity Purified |
| 性状 | Liquid |
| 缓冲液 | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| 纯度 | > 95% as determined by SDS-PAGE. |
| 研究背景 | Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Biotin/APC/PE/AF488/AF555/AF647 |
| 可提供抗体种类 | 2 |
| 免疫原 | KITLG |
| 抗原种属 | Human |
| 基因ID | 4254 |
| Uniprot ID | |
| 研究领域 | Cytokines |
| 分子量 | 150 kDa |
存储&运输
| 储存方式 | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| 运输方式 | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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