|
TMPK-00114
|
C-Reactive Protein /CRP Protein, Human, Recombinant (His)
C-reactive protein,MGC88244,PTX1MGC149895,CRP,pentraxin 1,PT...
|
Human
|
HEK293 Cells
|
|
C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate immunity, opsonization by its properties, complement activation and immunoglobulins receptor binding. CRP is a protein of the acute systemic inflammation and is, therefore, a prime marker of inflammation.The CRP is quantified by immunonephelometry or immunoturbidimetry. C-Reactiv... |
|
TMPJ-01172
|
IL-17 Protein, Mouse, Recombinant (His)
CTLA8,IL-17,IL-17A,Interleukin-17A,CTLA-8,Cytotoxic T-Lympho...
|
Mouse
|
HEK293 Cells
|
|
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid sequence identity with human and rat IL-17A, respectively. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumato... |
|
TMPJ-01461
|
IL-15RA & IL-15 Protein, Human, Recombinant (hFc)
IL-15 Receptor α & IL-15 Fusion Protein,Interleukin-15,IL15R...
|
Human
|
HEK293 Cells
|
|
IL15RA is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells.IL-15 is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 ... |
|
TMPJ-01462
|
IL-15RA & IL-15 Protein, Human, Recombinant - PBS Lyophilized (hFc)
IL15,IL15RA&IL15,IL-15,Interleukin-15,IL-15 Receptor α & IL-...
|
Human
|
HEK293 Cells
|
|
IL15RA is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells.IL-15 is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 ... |
|
TMPH-02567
|
CCL4 Protein, Mouse, Recombinant (His)
Immune activation protein 2,SIS-gamma,Mip1b,MIP-1-beta,ACT-2...
|
Mouse
|
E. coli
|
|
Monokine with inflammatory and chemokinetic properties. |
|
TMPH-03043
|
PIA Protein, MenB, Recombinant (His)
Major outer membrane protein P.IA,Class 1 protein,porA
|
MenB
|
E. coli
|
|
Serves as a slightly cation selective porin. Major antigen on the gonococcal cell surface and it may have pathogenic properties in addition to its porin activity. |
|
TMPK-01370
|
GRP-10 proform Protein, Canine, Recombinant (hFc)
Gastrin-releasing peptide,GRP
|
Canine
|
HEK293 Cells
|
|
Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties, and neuropeptides have previously been suggested to play a role in the complex cascade of chemical activity associated with periodontal inflammation. |
|
TMPH-03551
|
Exfoliative toxin A Protein, S. aureus, Recombinant (His)
eta,Epidermolytic toxin A,Exfoliative toxin A
|
Staphylococcus aureus
|
E. coli
|
|
Has serine protease-like properties and binds to the skin protein profilaggrin. Cleaves substrates after acidic residues. Exfoliative toxins cause impetigous diseases commonly referred as staphylococcal scalded skin syndrome (SSSS). |
|
TMPH-02932
|
Thrombospondin-2/THBS2 Protein, Mouse, Recombinant (E. coli, His)
Thrombospondin-2,Thbs2
|
Mouse
|
E. coli
|
|
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties. Thrombospondin-2/THBS2 Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 28.1 kDa and the accession number is Q03350. |
|
TMPH-02933
|
Thrombospondin-2/THBS2 Protein, Mouse, Recombinant (His)
Thrombospondin-2,Thbs2
|
Mouse
|
P. pastoris (Yeast)
|
|
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties. Thrombospondin-2/THBS2 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 26.1 kDa and the accession number is Q03350. |
|
TMPH-01709
|
Mucin-5B/MUC5B Protein, Human, Recombinant (His & Myc)
Mucin-5 subtype B, tracheobronchial,Mucin-5B,Sublingual glan...
|
Human
|
E. coli
|
|
Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus. Mucin-5B/MUC5B Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.9 kDa and the accession number is Q9HC84. |
|
TMPH-01599
|
LCTL Protein, Human, Recombinant (His & Myc)
Lactase-like protein,Klotho/lactase-phlorizin hydrolase-rela...
|
Human
|
E. coli
|
|
Plays a role in formation of the lens suture in the eye, which is important for normal optical properties of the lens. LCTL Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 67.2 kDa and the accession number is Q6UWM7. |
|
TMPH-03552
|
Exfoliative toxin B Protein, S. aureus, Recombinant (His & Myc)
etb,Epidermolytic toxin B,Exfoliative toxin B
|
Staphylococcus aureus
|
E. coli
|
|
Has serine protease-like properties and binds to the skin protein profilaggrin. Cleaves substrates after acidic residues. Exfoliative toxins cause impetigous diseases commonly referred as staphylococcal scalded skin syndrome (SSSS). Exfoliative toxin B Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.8 kDa and the accession number is P09332. |
|
TMPH-02591
|
COL4A3 Protein, Mouse, Recombinant (His & Myc)
Goodpasture antigen,Collagen alpha-3(IV) chain,COL4A3
|
Mouse
|
E. coli
|
|
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.; Tumstatin, a cleavage fragment corresponding to the collagen alpha 3(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity; these two anti-tumor properties may be regulated via RGD-independent ITGB3-mediated mechanisms. |
|
TMPK-00518
|
CD44 Protein, Cynomolgus, Recombinant (His)
CDw44,IN,MIC4,CD44,ECMR-III,CSPG8,HCELL,HUTCH-I,MC56,MDU2,Ep...
|
Cynomolgus
|
HEK293 Cells
|
|
CD44 is a hyaluronan binding cell surface signal transducing receptor that influences motility, cell survival and proliferation as well as the formation of tumor microenvironment. CD44 contains two variable regions encoded by variable exons. Alternative splicing, which is often deregulated in cancer, can produce various isoforms of CD44 with properties that may have different tissue specific effects and therefore even diverse effects on cancer progression |
|
TMPH-01290
|
ERVK-6 Protein, Human, Recombinant (His)
HERV-K(HML-2.HOM) envelope protein,ERVK-6,HERV-K(C7) envelop...
|
Human
|
Baculovirus Insect Cells
|
|
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its original fusogenic properties.; SU mediates receptor recognition.; TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane... |
|
TMPJ-00888
|
ANXA7 Protein, Human, Recombinant
Annexin A7,Annexin-7,Synexin,ANXA7,Annexin VII,SNX,ANX7
|
Human
|
E. coli
|
|
Annexin A7 (ANXA7) is a member of the annexin family of calcium-dependent phospholipid binding proteins. Annexin A7 has a unique, highly hydrophobic N-terminal domain and a conserved C-terminal region. The C-terminal region is composed of alternating hydrophobic and hydrophilic segments. Annexin A7 is a calcium/phospholipid-binding protein with diverse properties including voltage-sensitive calcium channel activity and promotes membrane fusion and is also involved in exocytosis. |
|
TMPH-01289
|
ERVK-6 Protein, Human, Recombinant (E. coli, His)
HERV-K108 envelope protein,Endogenous retrovirus group K mem...
|
Human
|
E. coli
|
|
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its original fusogenic properties.; SU mediates receptor recognition.; TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane... |
|
TMPY-02128
|
Serpin B1 Protein, Human, Recombinant (His)
HEL57,serpin peptidase inhibitor, clade B (ovalbumin), membe...
|
Human
|
Baculovirus Insect Cells
|
|
SerpinB1 is an endogenous inhibitor of serine proteases recognized for its anti-inflammatory and host-protective properties. Serum SerpinB1 levels are elevated in patients with type 2 diabetes compared with that in healthy subjects and are negatively correlated with serum LDL-C. serpinB1 as an endogenous protein that can potentially be harnessed to enhance functional beta cell mass in patients with diabetes. |
|
TMPK-00270
|
TPBG/5T4 Protein, Human, Recombinant (His & Avi), FITC-Labeled
WAIF1,TPBG,5T4AG,5T4,M6P1
|
Human
|
HEK293 Cells
|
|
The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR4/CXCL12, Wnt, and Hippo pathways which may all contribute through the mobilization of CSCs. TPBG/5T4 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 38.2 kDa and the accession numb... |
|
TMPK-00271
|
TPBG/5T4 Protein, Human, Recombinant (His & Avi)
M6P1,WAIF1,5T4,TPBG,5T4AG
|
Human
|
HEK293 Cells
|
|
The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR4/CXCL12, Wnt, and Hippo pathways which may all contribute through the mobilization of CSCs. TPBG/5T4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is Q13641-1... |
|
TMPH-00227
|
Beta-casein Protein, Bovine, Recombinant (His & Myc)
CSN2,Beta-casein
|
Bovine
|
E. coli
|
|
Important role in determination of the surface properties of the casein micelles.; Casoparan acts as a macrophage activator, increasing the phagocytic activity of macrophages and peroxide release from macrophages. It also acts as a bradykinin-potentiating peptide.; Casohypotensin acts as a bradykinin-potentiating peptide. Induces hypotension in rats. Acts as a strong competitive inhibitor of endo-oligopeptidase A.; Antioxidant peptide has antioxidant activity. Beta-casein Protein, Bovine, Recomb... |
|
TMPK-00545
|
HPX Protein, Cynomolgus, Recombinant (His)
Hemopexin,Hpx,Hpxn
|
Cynomolgus
|
HEK293 Cells
|
|
Hemopexin (HPX) serves as scavenger and transporter of toxic plasma heme to the liver. HPX is formed by two four-bladed beta-propeller domains, resembling two thick disks that lock together at a 90 degrees angle. The heme is bound between the two beta-propeller domains in a pocket formed by the interdomain linker peptide.HPX, acting not only as a heme carrier but also displaying transient heme-based ligand binding and (pseudo-)enzymatic properties, could be considered a 'chronosteric' heme-prote... |
|
TMPK-01413
|
H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi)
H-2K,OVA,MHC,H2-K1
|
Mouse
|
HEK293 Cells
|
|
Ovalbumin (OVA) has been historically a popular source of such antigens, since OVA can induce both humoral and cellular immune responses based on well-characterised peptide epitopes. The OVA257-264 octapeptide was one of the frst OVA epitopes to be characterised, it has an amino acid sequence SIINFEKL, which is recognised by cytotoxic T lymphocytes. SIINFEKL forms fbrillar assemblies similar to other peptide hydrogels. Te immunoactive properties of this peptide can therefore be related to its se... |
|
TMPY-03990
|
Profilin 4 Protein, Human, Recombinant (His)
profilin family, member 4
|
Human
|
E. coli
|
|
PFN4, also known as profilin 4, is a member of the profilin family. Profilin can be detected in all eukaryotic organisms. It plays an important role in the spatially and temporally controlled growth of actin microfilaments. Profilin is one of the most abundant actin monomer binders, but proteins such as CAP and (in mammals) thymosin β4 have some functional overlaps with profilin. In contrast, ADF/cofilin has some properties that antagonize profilin action. PFN4 also functions in the dynamic turn... |
|
TMPJ-00021
|
LGALS1 Protein, Human, Recombinant (His)
HPL,S-Lac Lectin 1,Lactose-Binding Lectin 1,14 kDa Lectin,Be...
|
Human
|
E. coli
|
|
Galectin-1 is a member of growing family of evolutionary conserved animal lectins. Galectin-1 is widely expressed in many cells and tissues. Galectins consists of a Galectin domain and two Beta-galactoside binding domains. Galectin-1 can binds LGALS3BP and interacts with CD2, CD3, CD4, CD7, CD43 and CD45. Galectin-1 may act as an autocrine negative growth factor which regulates apoptosis, cell proliferation and cell differentiation. In addition, Galectin-1 plays improtant roles in immunosuppress... |
|
TMPY-01692
|
NETO1 Protein, Human, Recombinant (His)
neuropilin (NRP) and tolloid (TLL)-like 1,BCTL1,BTCL1
|
Human
|
HEK293 Cells
|
|
Neuropilin tolloid-like 1 (NETO1), a complement C1r/C1s, Uegf, Bmp1 (CUB) domain-containing transmembrane protein, is a novel component of the NMDAR complex critical for maintaining the abundance of NR2A-containing NMDARs in the postsynaptic density. The N-methyl-D-aspartate receptor (NMDAR), a major excitatory ligand-gated ion channel in the central nervous system (CNS), is a principal mediator of synaptic plasticity. Both NETO1 and NETO2 share an identical and unique domain structure thus repr... |
|
TMPH-02205
|
Titin Protein, Human, Recombinant (His)
Connectin,TTN,Rhabdomyosarcoma antigen MU-RMS-40.14,Titin
|
Human
|
E. coli
|
|
Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to ch... |
|
TMPH-02540
|
GRK2 Protein, Mouse, Recombinant (His & SUMO)
Beta-adrenergic receptor kinase 1,Grk2,G-protein-coupled rec...
|
Mouse
|
E. coli
|
|
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and... |
|
TMPJ-00840
|
ANXA3 Protein, Human, Recombinant
Annexin III,Placental anticoagulant protein III,35-alpha cal...
|
Human
|
E. coli
|
|
Annexin A3（ANXA3）contains 4 annexin repeats and belongs to the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. ANXA3 is Inhibitor of phospholipase A2 and cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. ... |
|
TMPH-03740
|
DCL Protein, Bacillus subtilis, Recombinant (His)
DCL,D-alanine--poly(phosphoribitol) ligase subunit 1,dltA,DA...
|
Bacillus subtilis
|
E. coli
|
|
Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the... |
|
TMPK-01333
|
C-Reactive Protein /CRP Protein, Cynomolgus, Recombinant (His)
C-reactive protein,pentraxin 1,PTX1,PTX1MGC149895,MGC88244,C...
|
Cynomolgus
|
HEK293 Cells
|
|
C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate immunity, opsonization by its properties, complement activation and immunoglobulins receptor binding. CRP is a protein of the acute systemic inflammation and is, therefore, a prime marker of inflammation.The CRP is quantified by immunonephelometry or immunoturbidimetry. C-Reactiv... |
|
TMPJ-01371
|
Limitin Protein, Mouse, Recombinant (His)
Ifnz,Lmtn,IFN-z,IFN-ζ,BGIF,interferon ζ,IFN-zeta,Limitin,int...
|
Mouse
|
HEK293 Cells
|
|
Limitin, also called IFN-ζ, is a secreted interferon (IFN)-like glycoprotein. Limitin has approximately 30% sequence homology with IFN-α, IFN-β, and IFN-ω and binds to the IFN-α/β receptors. Like IFN-α and IFN-β, limitin has antiproliferative, immunomodulatory, and antiviral properties, it is unique in lacking influence on myeloid and erythroid progenitors. Similar dose requirement between limitin and IFN-α was observed for the enhancement of cytotoxic T lymphocyte activity, the augmentation of ... |
|
TMPJ-00766
|
ANXA1 Protein, Human, Recombinant
Chromobindin-9,Phospholipase A2 Inhibitory Protein,Annexin-1...
|
Human
|
E. coli
|
|
Annexin A1 is the first characterized member of the annexin family of proteins and is able to bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis. Annexin A1 has anti-inflammatory properties and inhibits phospholipase A2 activity. Annexin A1 also has roles in many diverse cellular functions, such as membrane aggregation, inflammation, phagocytosis, proliferation, apoptosis, and tumorigenesis and cancer development. ANXA1 is strongly expressed on th... |
|
TMPJ-00079
|
IL-11 Protein, Mouse, Recombinant (hFc)
IL-11,Il11,白细胞介素,白介素,Interleukin-11
|
Mouse
|
HEK293 Cells
|
|
Interleukin-11(IL-11) is a secreted protein and belongs to the IL-6 superfamily. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induceacute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cellproliferation and differentiation and could be use as a therapeutic for osteoporosis. IL-11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thicknes... |
|
TMPY-06864
|
GLP1R Protein, Human, Recombinant (His & Avi)
glucagon-like peptide 1 receptor
|
Human
|
HEK293 Cells
|
|
Glucagon-like peptide (GLP)-1 receptor is encoded by GLP1R. GLP1R plays a critical role in mediating the biological actions of GLP1 in mammals and fish. The neuronal GLP1Rs mediate body weight and anorectic effects of liraglutide, but are not required for glucose-lowering effects. Glucagon-like peptide 1 receptor (GLP1R) signaling has been shown to have antipsychotic properties in animal models and to impact glucose-dependent insulin release, satiety, memory, and learning in man. Glucagon-like p... |
|
TMPJ-00563
|
LGALS3 Protein, Human, Recombinant (His)
Galactose-Specific Lectin 3,LGALS3,35 kDa Lectin,Gal-3,MAC2,...
|
Human
|
HEK293 Cells
|
|
Galectin-3(LGALS3) is also known as Galactose-specific lectin 3, Mac-2 antigen, Carbohydrate-binding protein 35, Laminin-binding protein and Galactoside-binding protein. LGALS3 is highly expressed in early stages of papillary carcinoma, and lowly during tumor progression. LGALS3 is probably forms homo- or heterodimers and secreted by a non-classical secretory pathway and associates with the cell surface. LGALS3 plays an important role during the acquisition of vasculogenic mimicry and angiogenic... |
|
TMPJ-00022
|
LGALS7 Protein, Human, Recombinant
Galectin-7,Gal-7,LGALS7,PI7,PIG1,LGALS7B,p53-Induced Gene 1 ...
|
Human
|
E. coli
|
|
The Galectin family of proteins, with specificity for Nacetyllactosamine containing glycoproteins, consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs).They also possess hemagglutination activity, which is attributable to their bivalent carbohydrate binding properties. Galectins are active both intracellularly and extracellularly. Although they are localized primarily in the cytoplasm and lack a classical signal peptide; they can be secreted ... |
|
TMPJ-01433
|
Fibronectin Protein, Human, Recombinant (ED-B domain, Avi & His), Biotinylated
Fibronectin,FN1
|
Human
|
E. coli
|
|
Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components such as collagen, fibrin, and heparan sulfate proteoglycans. Fibronectin plays a major role in cell adhesion, growth, migration, and differentiation, and it is important for processes such as wound healing and embryonic development. Altered fibronectin expression, degradation, an... |
|
TMPY-03286
|
hnRNP-R Protein, Human, Recombinant (His & GST)
hnRNP-R,HNRPR,heterogeneous nuclear ribonucleoprotein R,HNRN...
|
Human
|
Baculovirus Insect Cells
|
|
HNRNP R, also known as HNRNPR, is an RNA binding protein. HNRNP R gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). HnRNPs complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The ... |
|
TMPJ-01000
|
CCL9 Protein, Mouse, Recombinant
Macrophage inflammatory protein 1-gamma,Macrophage inflammat...
|
Mouse
|
E. coli
|
|
C-C motif chemokine 9(CCL9) is an 11 kDa, secreted, monomeric polypeptide that belongs to the beta (or CC) intercrine family of chemokines. It is expressed mainly in the liver, lung, and the thymus, although some expression has been detected in a wide variety of tissues except brain. Monokine has inflammatory, pyrogenic and chemokinetic properties. It circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor，it activates calcium release in neutrophils... |
|
TMPJ-01444
|
IL-17A Protein, Cynomolgus, Recombinant (His)
CTLA-8,CTLA8,IL17A,IL-17,IL-17A,Cytotoxic T-Lymphocyte-Assoc...
|
Cynomolgus
|
HEK293 Cells
|
|
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synt... |
|
TMPJ-00499
|
GSTP1 Protein, Human, Recombinant
GSTP1,GST3,GST class-pi,Glutathione S-transferase P,FAEES3,G...
|
Human
|
E. coli
|
|
Glutathione S-transferase P (GSTP1) is an enzyme that contains 1 GST C-terminal domain, 1 GST N-terminal domain. GSTP1 belongs to the GST superfamily, the GSTs are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione ... |
|
TMPJ-00554
|
Vinculin Protein, Human, Recombinant
Metavinculin,VCL,Vinculin
|
Human
|
E. coli
|
|
Vinculin is a focal adhesion and cytoskeletal protein that distributed mainly at cell-cell junctions and cell-extracellular matrix (ECM) adhesion that belongs to the Vinculin/α-Catenin family. Vinculin is an Actin-binding protein and component of the Actin-Linking Functional module that senses and feels the mechanical properties of the extracellular environment. Vinculin is also a key factor that couples, transmits, transduces, and regulates mechanical force between the cytoskeleton and adhesion... |
|
TMPJ-01055
|
HBA1 Protein, Human, Recombinant (His)
α-globin,Hemoglobin subunit alpha,HBH,HBA-T3,Alpha-globin,He...
|
Human
|
E. coli
|
|
Hemoglobin subunit alpha 1 (HBA1), also known as α2β2, is a hetero-tetramer consisting of two α and two β subunits held together by non-covalent interactions. Each subunit contains a heme group with an iron atom in the Fe2+ state. Cooperativity of Hemoglobin (Hb) in binding with O2 and allosteric regulatory binding properties with CO2, H+, Cl−, and 2,3-DPG (2,3-bisphosphoglycerate) are based on subunit interactions. HBA1 is the most common type of Hb in adult humans, which mediates the transport... |
|
TMPY-01586
|
ACPL2 Protein, Human, Recombinant (His)
ACPL2,UNQ37/PRO76,FLJ23751
|
Human
|
HEK293 Cells
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acid phosphatase-like protein 2, also known as ACPL2, is a secreted protein which belongs to thehistidine acid phosphatase family. A large-scale effort, termed the Secreted Protein Discovery Initiative (SPDI), was undertaken to identify novel secreted and transmembrane proteins. In the first of several approaches, a biological signal sequence trap in yeast cells was utilized to identify cDNA clones encoding putative secreted proteins. A second strategy utilized various algorithms that rec... |
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TMPJ-00602
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CPA2 Protein, Human, Recombinant (His)
CPA2,Carboxypeptidase A2
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Human
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HEK293 Cells
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Carboxypeptidase A2 (CPA) is a secreted pancreatic procarboxy-peptidase that cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group. The hydrolytic action of CPA2 was identified with a preference towards long substrates with aromatic amino acids in their C-terminal end, particularly tryptophan. CPA2 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. Three different forms of human pancreat... |
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TMPJ-00277
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NgR3 Protein, Human, Recombinant (His)
NGRL2,Nogo Receptor-Like 2,Reticulon-4 Receptor-Like 1,NgR3,...
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Human
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HEK293 Cells
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Nogo-66 Receptor-Related Protein 3 (NgR3) has primary structures with NgR2 (NgRH1, NgRL3) and biochemical properties that are homologous to Nogo-66 receptor (NgR), and constitute a novel neuronal receptor protein family. NgR is GPI-anchored and contains eight leucine-rich repeats (LRR), it is the neuronal receptor for the myelin- associated proteins Nogo-A, OMgp (oligodendrocyte myelin glycoprotein), and MAG (myelin-associated glycoprotein) and mediates the inhibition of CNS axonal regeneration ... |
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TMPJ-00072
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IL-18BPd Protein, Mouse, Recombinant (hFc)
Interleukin 18 Binding Protein Isoform d,IL-18 BPd,Igifbp,In...
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Mouse
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HEK293 Cells
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Interleukin 18 binding protein (IL-18BP) is a physiological inhibitor that acts through binding to the receptor-binding site of IL-18. IL-18 stimulates INF-γ, which then stimulates 18BP production via NF-κB. The interaction between IL-18 and IL-18BP has a significant role in the inflammation process. IL-18 BPs have four isoforms, a, b, c and d, which are spliced by different ways. The IL-18 BP isoforms a and c each contain one immunoglobulin (Ig)-like C2-type domain which is essential to the bin... |
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TMPH-02163
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Syncytin-1 Protein, Human, Recombinant (His & SUMO)
Endogenous retrovirus group W member 1,Enverin,Env-W,Syncyti...
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Human
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E. coli
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This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5.; Endogenous envelope proteins may have kept, lost or modified their original function during evolution. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein (SU) mediates receptor r... |
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