Riboxin (IDP), an orally administered purine derivative known as hypoxanthine riboside, exhibits antihypoxic and antihyperthermic effects. Furthermore, it demonstrates antiarrhythmic properties in cats, rabbits, and mice suffering from Ouabain-induced cardiac rhythm abnormalities. Additionally, Riboxin offers protection to animals from the harmful consequences of γ-irradiation [1] [2].

Riboxin（250 mg/kg；口服；单剂量）能延长小鼠的游泳耐力，但力量耐力未见明显改善。在相同剂量下，能提升热室试验中的小鼠存活率[1]。每日一次连续六日给予Riboxin（50 mg/kg；口服）后，小鼠的活动时间延长，但游泳及跑步能力未受显著影响[1]。给药前一小时，Riboxin（250 mg/kg；口服）对小鼠提供了显著的γ辐射保护[1]。