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OT-551 HCl 是一种 NF-Κb 抑制剂,是一种具有抗氧化特性的二取代羟胺可用于治疗白内障和老年性黄斑变性和地域性萎缩 (GA)。
OT-551 HCl 是一种 NF-Κb 抑制剂,是一种具有抗氧化特性的二取代羟胺可用于治疗白内障和老年性黄斑变性和地域性萎缩 (GA)。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 1,300 | 现货 | |
5 mg | ¥ 2,900 | 现货 | |
10 mg | ¥ 4,290 | 现货 | |
25 mg | ¥ 6,850 | 现货 | |
50 mg | ¥ 9,270 | 现货 | |
100 mg | ¥ 12,500 | 现货 | |
500 mg | ¥ 24,800 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 3,350 | 现货 |
产品描述 | OT-551 HCl is an NF-Κb inhibitor, a disubstituted hydroxylamine with antioxidant properties can be used for the treatment of cataracts and age-related macular degeneration and geographic atrophy (GA). |
体内活性 | OT-551 HCl (intraperitoneally injected; rats; approximately 30 min prior to a 6 h exposure to 2700 lux white fluorescent light) significantly reduced the number of RPE cell nuclei in light-exposed eyes from water-treated animals. RPE damage index was significantly lower in the animals treated with any dose of OT-551 HCl compared to water-treated animals both in the inferior and superior hemispheres. Systemic administration of OT-551 HCl provides RPE cell protection against acute light damage.[1] |
别名 | OT-551 HCl(627085-11-4 Free base) |
分子量 | 277.79 |
分子式 | C13H24ClNO3 |
CAS No. | 627085-15-8 |
Smiles | Cl.CC1(C)CC(CC(C)(C)N1O)OC(=O)C1CC1 |
存储 | Shipping with blue ice. | ||||||||||||||||||||
溶解度信息 | DMSO: 3.60 mg/mL (12.96 mM) | ||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||
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