USP1-IN-4

Name: USP1-IN-4
Brand: TargetMol
SKU: T87600
Price: 133 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T87600Cas号 2878441-72-4

USP1-IN-4（compound 10）是一种IC50为2.44 nM的USP1抑制剂，具备抗癌活性，并且与多种抗癌药物表现出协同效应。

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产品编号 T87600Cas号 2878441-72-4

USP1-IN-4（compound 10）是一种IC50为2.44 nM的USP1抑制剂，具备抗癌活性，并且与多种抗癌药物表现出协同效应。

规格	价格	库存	数量
10 mg	询价	10-14周
50 mg	询价	10-14周

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产品介绍

生物活性

产品描述	USP1-IN-4 (compound 10) serves as a potent inhibitor of USP1, exhibiting an IC 50 of 2.44 nM. It demonstrates anticancer properties and operates synergistically with various anticancer drugs [1].
靶点活性	USP1:2.44 nM
体外活性	USP1-IN-4, at concentrations ranging from 0.0005 to 10 μM, significantly inhibits USP1/UAF1 activity with an IC50 of 2.44 nM following a 15-minute treatment [1]. Additionally, USP1-IN-4 impedes the growth of MDA-MB-436 cells over a 7-day period, also within the 0.0005 to 10 μM range, yielding an IC50 of 103.75 nM [1]. In a cell viability assay using the MDA-MB-436 cell line, a concentration range of 0.0005 to 10 μM was used, and cell growth inhibition was observed with an IC50 of 103.75 nM.