ω-Hydroxy-DEET

Name: ω-Hydroxy-DEET
Brand: TargetMol
SKU: T40833
Price: 1300 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T40833Cas号 72236-22-7

ω-Hydroxy-DEET, a significant metabolite of the insect repellent N-N-diethyl-meta-toluamide (DEET), exhibits anti-proliferative properties. DEET, renowned for being a spatial repellent and irritant, is frequently employed to deter mosquito contact.

ω-Hydroxy-DEET

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产品编号 T40833Cas号 72236-22-7

规格	价格	库存	数量
2 mg	¥ 882	5日内发货

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产品介绍

生物活性

产品描述	ω-Hydroxy-DEET, a significant metabolite of the insect repellent N-N-diethyl-meta-toluamide (DEET), exhibits anti-proliferative properties. DEET, renowned for being a spatial repellent and irritant, is frequently employed to deter mosquito contact.
体外活性	Hepatoma cell studies reveals that ω-Hydroxy-DEET (DHMB; 0.1-10 μg/mL; 48-72 hours) treatments decreases cellular proliferation[1].
体内活性	The metabolite ω-Hydroxy-DEET (DHMB) is extensively distributed following intravenous and topical skin administration of DEET in rats. The ω-Hydroxy-DEET appeared to be the major metabolite for DEET. Repeated once-daily topical application for 30 days lead to higher concentrations of ω-Hydroxy-DEET in the liver[1].