Claficapavir

Name: Claficapavir
Brand: TargetMol
SKU: T61819
Price: 255 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T61819Cas号 2055732-24-4

Claficapavir (A1752) is a potent nucleocapsid protein (NC) inhibitor that effectively binds the HIV-1 NC with a dissociation constant (Kd) of 20 nM, resulting in the inhibition of its chaperone properties. This specific molecular interaction leads to strong antiviral activity against HIV-1, with an IC50 of approximately 1 μM [1].

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Claficapavir

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产品编号 T61819Cas号 2055732-24-4

规格	价格	库存
2 mg	¥ 692	5日内发货
5 mg	¥ 1,150	5日内发货
10 mg	¥ 2,180	5日内发货
100 mg	¥ 9,980	6-8周
1 mL x 10 mM (in DMSO)	¥ 1,180	5日内发货

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产品介绍

生物活性

产品描述	Claficapavir (A1752) is a potent nucleocapsid protein (NC) inhibitor that effectively binds the HIV-1 NC with a dissociation constant (Kd) of 20 nM, resulting in the inhibition of its chaperone properties. This specific molecular interaction leads to strong antiviral activity against HIV-1, with an IC50 of approximately 1 μM [1].
体外活性	Claficapavir binds directly to HIV-1 NC, thereby inhibiting specific chaperone functions of NC including Psi RNA dimerization and complementary trans-activation response element (cTAR) DNA destabilization, and it also disrupts the proper Gag processing [1].