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TLR4/NF-κB-IN-1 (Compound 7x) 是一种可口服的TLR4/NF-κB信号通路抑制剂,具有抗炎活性,能够穿过血脑屏障。TLR4/NF-κB-IN-1 可减轻LPS引发的小鼠急性神经炎症,降低TLR4、P-NF-κB和P-IκB-α蛋白的表达。
TLR4/NF-κB-IN-1 (Compound 7x) 是一种可口服的TLR4/NF-κB信号通路抑制剂,具有抗炎活性,能够穿过血脑屏障。TLR4/NF-κB-IN-1 可减轻LPS引发的小鼠急性神经炎症,降低TLR4、P-NF-κB和P-IκB-α蛋白的表达。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | TLR4/NF-κB-IN-1 (Compound 7x) is an orally bioavailable inhibitor targeting the TLR4/NF-κB signaling pathway, with anti-inflammatory properties and the ability to cross the blood-brain barrier. It can alleviate LPS-induced acute neuroinflammation in mice and downregulate the protein expression of TLR4, P-NF-κB, and P-IκB-α. |
分子量 | 374.37 |
分子式 | C20H15FN6O |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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