Rufigallol (AI3-00865) is an electron-deficient disk-shaped molecule with six hydroxyl groups and is a good unit for inducing the formation of DLC from non-planar AIE molecules, an anthraquinone derivative.Rufigallol induces the acquisition of DLC properties, while the introduction of TPE groups gives the molecular structure good fluorescence in the aggregated state.The remarkable synergistic in vitro antimalarial effect, in vivo with vitamin C and ketones was synergistic and showed antimalarial activity.

Rufigallol（一种蒽醌衍生物）和exifone（一种苯酮衍生物）在体外展现出显著的协同抗疟疾效果。我们在感染了贝氏疟原虫的小鼠中，联合使用rufigallol进行了抗疟疾测试。结果表明，20种酮类化合物中有9种在体内测试中，与rufigallol联用时显示出良好的抗疟疾活性，证明了它们之间的协同作用。[1]