Hydroxydione, a neuroactive steroid with general anesthetic properties, is utilized in anesthesia-related research [1] [2].

Hydroxydione 增加 hexobarbital 麻醉的持续时间，而重复给予 hexobarbital 剂量则会降低 hydroxydione 麻醉的持续时间 [1]。Hydroxydione（5-100 mg/kg; 静脉注射一次）可引起短暂性低血压，且对心率减慢的效应不大，同时对呼吸有影响 [2]。