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Targets Recommended: Others

3854

抑制剂 & 化合物

48

天然产物

46

化合物库

98

重组蛋白

6

同位素标记化合物

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Cat. No. Product Name
L3600 细胞因子抑制剂库

604 compounds
604 个与细胞因子紧密相关的化合物集合,是高通量、高内涵筛选的良好载体;
L1110 微管靶向化合物库

142 compounds
142 种靶向微管的分子集合,用于高通量筛选和高内涵筛选;
L2521 糖酵解化合物库

555 compounds
555 种糖酵解相关的活性化合物,可用于高通量和高内涵筛选
L8300 染色质修饰分子库

250 compounds
250 种染色质化学修饰相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L4660 神经疾病库Plus

1246 compounds
1246 种神经系统相关、结构新颖的化合物;
L1300 PI3K/Akt/mTOR 化合物库

420 compounds
420 种与PI3K/Akt/mTOR 相关的生物活性小分子化合物的特有集合,用于PI3K/Akt/mTOR 相关研究以及高通量、高内涵筛选;
L1400 MAPK 抑制剂库

365 compounds
365 种与MAPK 信号通路相关的生物活性小分子化合物的特有集合,可用于高通量筛选和高内涵筛选;
L5200 抗代谢疾病化合物库

1544 compounds
1544 个代谢疾病相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L7200 钙通道分子库

140 compounds
140 种钙通道相关化合物的独特集合,可用于高通量筛选和高内涵筛选;
L1610 FDA 上市激酶抑制剂库

263 compounds
263种靶向激酶的上市药物集合,用于特定靶向激酶,可用于高通量筛选和高内涵筛选;
L2400 内分泌激素分子库

784 compounds
784 种与内分泌系统相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L4510 抗寄生虫库

419 compounds
419 种具有抗寄生虫活性的小分子化合物;
L2300 离子通道库

931 compounds
931 种与离子通道相关的生物活性小分子化合物的特有集合,用于离子通道相关的疾病和药物研究,可用于高通量筛选和高内涵筛选;
L2520 糖代谢化合物库

702 compounds
702 种糖代谢相关的化合物,可用于高通量和高内涵筛选;
L2800 5-羟色胺分子库

268 compounds
268 种生物活性小分子化合物,用于高通量、高内涵筛选;
L1510 核受体化合物库

531 compounds
531 个核受体作用化合物的独特集合,可用于高通量筛选和高内涵筛选;
L2191 抗乳腺癌化合物库

1939 compounds
1939 种与乳腺癌相关的化合物,可以用于抗乳腺癌药物研发和药理研究;
L2600 神经信号分子库

2540 compounds
2540 种CNS 相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L2152 靶向治疗药物库

119 compounds
119 个肿瘤靶向治疗药物,可以用于高通量和高内涵筛选;
L2200 酪氨酸激酶分子库

1016 compounds
1016 种酪氨酸激酶抑制剂的独特集合,可用于高通量筛选和高内涵筛选;
L2170 肿瘤免疫治疗小分子化合物库

449 compounds
449 种靶向肿瘤免疫治疗靶点的小分子,可用于高通量和高内涵筛选,是研究肿瘤免疫治疗的有力工具;
L5300 线粒体靶向库

812 compounds
812 种具有潜在或确定线粒体靶向活性的化合物,以促进针对线粒体的药物研究;
L2192 抗胰腺癌化合物库

2238 compounds
2238 种与胰腺癌相关的化合物,可以用于高通量和高内涵筛选;
L3800 NF-κB 通路分子库

729 compounds
729 个 NF-κB 信号通路相关的小分子化合物的特有集合,用于高通量、高内涵筛选;
L8600 泛素化化合物库

210 compounds
210 种泛素化相关的小分子,用于高通量和高内涵筛选;
L3700 JAK-STAT 化合物库

252 compounds
252 个 JAK/STAT 靶点相关的小分子化合物的独特集合,用于高通量、高内涵筛选;
L1120 AMPK靶向分子库

80 compounds
80 个靶向AMPK 的分子集合,可用于高通量和高内涵筛选;
L5900 血脑屏障通透化合物库

509 compounds
509 个 CNS-Penetrant 生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L8710 铜死亡化合物库

400 compounds
TargetMol 铜死亡化合物库集合了 400 种与铜死亡相关的化合物,可以用于铜死亡机制及相关疾病研究
L2190 抗肺癌化合物库

1702 compounds
1702 种与肺癌相关的化合物,可以用于抗肺癌药物研发和药理研究;
L2700 肾上腺素能受体化合物库

193 compounds
193 种特异靶向肾上腺素受体的生物活性小分子化合物的集合,是相关疾病药物筛选的有效工具;
L7400 钠通道分子库

118 compounds
118 种钠通道相关化合物的独特集合,可用于高通量筛选和高内涵筛选;
L2130 抗癌细胞代谢库

1268 compounds
1268 种癌细胞代谢相关的生物活性小分子化合物的特有集合,用于肿瘤相关的研究以及抗肿瘤药物的筛选,用于高通量、高内涵筛选;
L2501 人内源代谢化合物库 Plus

1283 compounds
1283种内源性生物活性化合物的独特集合,用于高通量、高内涵筛选。
L9700 内质网应激化合物库

193 compounds
193 个内质网应激相关的化合物集合,可用于高通量和高内涵筛选;
L4300 Wnt/Hedgehog/Notch 通路化合物库

237 compounds
237 个Wnt & Hedgehog & Notch 靶点相关的生物活性小分子化合物的特有集合,用于相关通路的研究及药物的筛选,可用于高通量、高内涵筛选。
L1380 转录因子库

695 compounds
695 种转录因子靶向、结构新颖的化合物;
L2194 抗结直肠癌化合物库

1545 compounds
1545 种与结直肠癌相关的化合物,可以用于高通量和高内涵筛选;
L3980 DNA损伤/修复库Plus

667 compounds
667 种 DNA 损伤/修复靶向、结构新颖的化合物;
L7600 趋化因子抑制剂库

59 compounds
59 种趋化因子或其受体抑制剂的独特集合,可用于高通量筛选和高内涵筛选;
L1580 GPCR库Plus

338 compounds
338 种GPCR 靶向、结构新颖的化合物;
L9840 抗阿尔茨海默症化合物库

986 compounds
986 种阿尔茨海默症相关的化合物集合,可用于高通量和高内涵筛选;
L6710 中药抗炎分子库

1246 compounds
1246 种具有抗炎活性或靶向炎症相关靶点的中药单体集合,是药物开发、药理研究的有效工具;
L3300 组胺&褪黑色素化合物库

153 compounds
153 种生物活性小分子化合物,用于高通量、高内涵筛选;
L2550 谷氨酰胺代谢化合物库

565 compounds
565 种谷氨酰胺代谢相关的分子,可以用于高通量和高内涵筛选;
L2510 脂代谢化合物库

492 compounds
492 个脂代谢相关的化合物集合,可用于高通量和高内涵筛选;

化合物库

细胞因子抑制剂库
Cat.No: L3600
Compounds: 604
微管靶向化合物库
Cat.No: L1110
Compounds: 142
糖酵解化合物库
Cat.No: L2521
Compounds: 555
染色质修饰分子库
Cat.No: L8300
Compounds: 250
神经疾病库Plus
Cat.No: L4660
Compounds: 1246
PI3K/Akt/mTOR 化合物库
Cat.No: L1300
Compounds: 420
MAPK 抑制剂库
Cat.No: L1400
Compounds: 365
抗代谢疾病化合物库
Cat.No: L5200
Compounds: 1544
钙通道分子库
Cat.No: L7200
Compounds: 140
FDA 上市激酶抑制剂库
Cat.No: L1610
Compounds: 263
内分泌激素分子库
Cat.No: L2400
Compounds: 784
抗寄生虫库
Cat.No: L4510
Compounds: 419
离子通道库
Cat.No: L2300
Compounds: 931
糖代谢化合物库
Cat.No: L2520
Compounds: 702
5-羟色胺分子库
Cat.No: L2800
Compounds: 268
核受体化合物库
Cat.No: L1510
Compounds: 531
抗乳腺癌化合物库
Cat.No: L2191
Compounds: 1939
神经信号分子库
Cat.No: L2600
Compounds: 2540
靶向治疗药物库
Cat.No: L2152
Compounds: 119
酪氨酸激酶分子库
Cat.No: L2200
Compounds: 1016
肿瘤免疫治疗小分子化合物库
Cat.No: L2170
Compounds: 449
线粒体靶向库
Cat.No: L5300
Compounds: 812
抗胰腺癌化合物库
Cat.No: L2192
Compounds: 2238
NF-κB 通路分子库
Cat.No: L3800
Compounds: 729
泛素化化合物库
Cat.No: L8600
Compounds: 210
JAK-STAT 化合物库
Cat.No: L3700
Compounds: 252
AMPK靶向分子库
Cat.No: L1120
Compounds: 80
血脑屏障通透化合物库
Cat.No: L5900
Compounds: 509
铜死亡化合物库
Cat.No: L8710
Compounds: 400
抗肺癌化合物库
Cat.No: L2190
Compounds: 1702
肾上腺素能受体化合物库
Cat.No: L2700
Compounds: 193
钠通道分子库
Cat.No: L7400
Compounds: 118
抗癌细胞代谢库
Cat.No: L2130
Compounds: 1268
人内源代谢化合物库 Plus
Cat.No: L2501
Compounds: 1283
内质网应激化合物库
Cat.No: L9700
Compounds: 193
Wnt/Hedgehog/Notch 通路化合物库
Cat.No: L4300
Compounds: 237
转录因子库
Cat.No: L1380
Compounds: 695
抗结直肠癌化合物库
Cat.No: L2194
Compounds: 1545
DNA损伤/修复库Plus
Cat.No: L3980
Compounds: 667
趋化因子抑制剂库
Cat.No: L7600
Compounds: 59
GPCR库Plus
Cat.No: L1580
Compounds: 338
抗阿尔茨海默症化合物库
Cat.No: L9840
Compounds: 986
中药抗炎分子库
Cat.No: L6710
Compounds: 1246
组胺&褪黑色素化合物库
Cat.No: L3300
Compounds: 153
谷氨酰胺代谢化合物库
Cat.No: L2550
Compounds: 565
脂代谢化合物库
Cat.No: L2510
Compounds: 492
Cat. No. Product Name Target Signaling Pathways
T13572 Cancer-Targeting Compound 1

Others Others
Cancer-Targeting Compound 1可用于激素相关癌症的研究,包括治疗或预防肌瘤、子宫平滑肌瘤、多囊卵巢综合征或激素依赖性癌等等。
T10071 Itch-Targeting Compound 1

Others Others
Itch-Targeting Compound 1是一种止痒化合物,对昆虫叮咬的反应、对环境过敏原的反应、皮肤感染、外部恶臭或肾透析患者发生的瘙痒均可有效预防或治疗。
T13573 Arrhythmias-Targeting Compound 1

Others Others
Arrhythmias-Targeting Compound 1 is a compound. It is used in the research of arrhythmias.
T13900 Arrhythmic-Targeting Compound 1

Others Others
Arrhythmic-Targeting Compound 1 is used for arrhythmic disease, with nitrogen-containing spirocycles.
T13491 Neuromuscular-targeting compound 1

Others Others
Neuromuscular-targeting compound 1 可用于研究肌肉萎缩和神经肌肉相关疾病。
T13486 Neurodegenerative Disorder-Targeting Compound 1

Others Others
Neurodegenerative Disorder-Targeting Compound 1 是一种靶向 calpain 的抑制剂。
T19417 Urinary Incontinence-Targeting Compound 1

Others Others
Urinary Incontinence-Targeting Compound 1, used in the research of urinary incontinence, is a sulfonanilide derivative.
T10059 Neuromuscular Disorder-Targeting Compound 1

Others Others
Neuromuscular Disorder-Targeting Compound 1 is a compound used in the research of neuromuscular disorders, for example, symptoms of chronic fatigue syndrome and fibromyalgia syndrome.
T83724 TPP-1 hydrochloride

Targeting PD-L1 Peptide

TPP-1是一种针对程序化细胞死亡蛋白1(PD-1)及其配体PD-1配体(PD-L1)之间蛋白-蛋白相互作用的肽抑制剂。它在无细胞实验中结合到PD-L1(Kd = 94.67 nM)。TPP-1 (20 µM)能逆转PD-L1在抗CD3激活的人类CD4+ T细胞中所引起的干扰素γ(IFN-γ)水平的下降。在使用HL-60白血病细胞与抗CD3激活的人类CD4+ T细胞共培养并在植入前预处理时,以4 mg/kg的剂量给药,可减少小鼠异种移植模型中的肿瘤体积。
T83857 Soluble Epoxide Hydrolase PROTAC 1a

sEH Proteolysis-targeting Chimera 1a,Soluble Epoxide Hydrolase Proteolysis-targeting Chimera 1a,sEH PROTAC 1a

Others Others
Soluble epoxide hydrolase (sEH) PROTAC 1a是一种利用蛋白质降解靶向嵌合体(PROTAC)技术,通过连接区域将cereblon配体1与sEH抑制剂t-TUCB结合。该化合物通过促进sEH的降解,特异性抑制sEH的水解酶活性(IC50 = 0.8 nM),相较于其磷酸酶活性(IC50 = >10,000 nM)具有较高选择性。sEH PROTAC 1a还特定促进细胞质中而非过氧体中的sEH降解,并通过溶酶体而非蛋白酶体实现其降解。它能够降低thapsigargin诱导的HepG2与293T细胞中磷酸化的inositol-requiring enzyme 1α (IRE1α)水平和X-box结合蛋白1 (XBP1)剪接,表明能减少ER应激。
T83527 (Rac)-Neurodegenerative Disorder-Targeting Compound 1

Others Others
(Rac)-Neurodegenerative Disorder-Targeting Compound 1为一种针对神经退行性疾病的化合物,具有calpain抑制活性。
T76218 Targeting the bacterial sliding clamp peptide 46

Others Others
Targeting bacterial sliding clamp peptide 46是一种抗菌肽,专门针对细菌的滑动夹蛋白(SC)而设计,其功能是阻断SC依赖的DNA合成作用。
T11249L Dxd

Exatecan derivative for ADC,OQM5SD32BQ,UNII-OQM5SD32BQ

Topoisomerase; ADC Cytotoxin Antibody-drug Conjugate/ADC Related; DNA Damage/DNA Repair
Dxd (OQM5SD32BQ) 是一种有效的DNA 拓扑异构酶 I 抑制剂,IC50值为 0.31 μM,用作HER2靶向ADC 的偶联药物。
T60015 TSPO ligand-2 

Carbonic acid

AUTACs PROTAC
TSPO ligand-2 (Carbonic acid) 是 AUTAC1 的配体,AUTAC1含有一个对氟苄基鸟嘌呤和一个烟曲霉醇部分。
T22282 Brr2-IN-3

Brr2 Inhibitor 9,Brr2 Inhibitor C9

Others Others
Brr2-IN-3 (Brr2 Inhibitor C9) 是选择性 Brr2解旋酶变构抑制剂。它呈剂量依赖性地抑制解旋酶(IC50:1.3 μM)。
T18893 5(6)-Carboxyfluorescein

5(6)-羧基荧光素,5-(and-6)-Carboxyfluorescein mixed isomers,5(6)-FAM

Others Others
5(6)-Carboxyfluorescein (5-(and-6)-Carboxyfluorescein mixed isomers) 是一种胺反应性 pH 敏感的绿色荧光标记物,能够标记蛋白质、多肽和氨基酸,可用于体内实验检测肿瘤位置。
T6804 Chetomin

Chaetomin,NSC289491,BRN0077366

Apoptosis; HSP; HIF Angiogenesis; Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism
Chetomin (BRN0077366) 是球毛壳菌的活性成分,是一种无毒的非小细胞肺癌干细胞靶向分子。它是一种热休克蛋白90/缺氧诱导因子1α 途径的抑制剂。
T39370 tri-GalNAc-COOH

LYTACs PROTAC
Tri-GalNAc-COOH is a ligand for the asialoglycoprotein receptor (ASGPR) commonly employed in Lysosome Targeting Chimera (LYTAC) investigations.
T6409 ALK kinase inhibitor-1

SAR348830

Others Others
SAR348830 是间变性淋巴瘤激酶ALK 抑制剂。
T60075 Dopamine D2 receptor agonist-2

Dopamine D2 Receptor

Dopamine Receptor GPCR/G Protein; Neuroscience
Dopamine D2 receptor agonist-2 (Dopamine D2 Receptor) 是靶向多巴胺D2受体的配体。
T5374 NAcM-OPT

E1/E2/E3 Enzyme; NEDD8 Metabolism; Ubiquitination
NAcM-OPT 是口服活性、有效的 cullin neddylation 1 抑制剂,可以抑制 DCN1-UBE2M 相互作用。
T10531 BGB-102

JNJ-26483327

EGFR; VEGFR; FLT; Src Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
BGB-102 (JNJ-26483327) 是一种针对FLT3 和 YES1 的激酶抑制剂和 针对 EGFR 和 VEGFR3 的拮抗剂,可用于研究黄斑变性和与遗传病与畸形相关的疾病。
TNU0123 5-Methoxyuridine

Mo5U

Apoptosis Apoptosis
5-Methoxyuridine (Mo5U) is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting malignant tumors of the inert lymphatic system and inducing apoptosis.5-Methoxyuridine's anticancer mechanism is dependent on the inhibition of DNA synthesis.5-Methoxyuridine is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting malignant tumors of the inert lymphatic system and inducing apoptosis.
T5451 Eph inhibitor 2

Ehp-inhibitor-1

Ephrin Receptor Tyrosine Kinase/Adaptors
Eph inhibitor 2 是一种 Eph 家族酪氨酸激酶抑制剂。
T1832 Walrycin B

Antibacterial; Antibiotic Microbiology/Virology
Walrycin B 是一种能特异地靶向WalR 应答调节子的新型抗菌素。
T5452 Ehp-inhibitor-2

Ephrin Receptor Tyrosine Kinase/Adaptors
Ehp-inhibitor-2 是一种靶向 Eph 受体的 Eph 家族酪氨酸激酶抑制剂。
T9584 UNC6934

Others; Histone Methyltransferase Chromatin/Epigenetic; Others
UNC6934 是一种针对 NSD2 的 N 端 PWWP (PWWP1) 结构域的化学探针,可定位核仁。
T25549 JCP174

JCP 174,JCP-174

Serine Protease Proteases/Proteasome
JCP174是一种去棕榈酰化酶抑制剂,可通过靶向 TgPPT1增强弓形虫的宿主细胞侵袭。
TP2065L α-Conotoxin PIA acetate

AChR Neuroscience
α-Conotoxin PIA acetate 是烟碱型乙酰胆碱受体 (nAChR) 的拮抗剂,主要针对 α6 和 α3 亚基。
T13142L Theodrenaline hydrochloride

Theodrenaline hydrochloride(13460-98-5 Free base)

SARS-CoV Microbiology/Virology
Theodrenaline hydrochloride 是一种靶向 SARS-CoV-2 的抑制剂,可用于研究由脊髓麻醉引起的低血压。
T12257 NSC 146109 hydrochloride

Apoptosis; Others Apoptosis; Others
NSC 146109 hydrochloride 是一种靶向 MDMX 的 p53 激活剂。 NSC 146109 hydrochloride 可用于乳腺癌研究。
T8955 PCNA-I1

Others Others
PCNA-I1 是PCNA(增殖细胞核抗原)抑制剂。它能够直接与 PCNA 三聚体结合(Kd:0.41 μM),在体内外均表现出抗肿瘤活性。
T9927 Panitumumab

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Panitumumab 是一种重组全人源 IgG2 单克隆抗体,可与表皮生长因子(EGFR)结合,具有抗肿瘤活性。
T13601 CDD3506

1-TRITYL-1H-IMIDAZOL-4-AMINE

P450 Metabolism
CDD3506 (1-TRITYL-1H-IMIDAZOL-4-AMINE) 能够诱导肝CYP3A 的活动,增强高密度脂蛋白胆固醇的水平。
T20022 Cephalexin monohydrate

Cephalexin hydrate,Cephacillin hydrate,Cefalexin hydrate

Antibiotic Microbiology/Virology
Cephalexin monohydrate (Cephalexin hydrate) 是一种可口服的半合成头孢菌素类抗生素,具有显著的抗菌活性, 通过靶向青霉素结合蛋白 (PBPs)抑制细菌增殖。
T12551 PROTAC BRD4 ligand-1

Epigenetic Reader Domain; Ligands for Target Protein for PROTAC Chromatin/Epigenetic; PROTAC
PROTAC BRD4 ligand-1 是 PROTAC GNE-987 靶向 BRD4 蛋白的配体,也是一种 BET 的抑制剂。
T9383 Pomalidomide-PEG2-OH

1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-(2-hydroxyethoxy)ethyl]amino]-

PROTACs PROTAC
Pomalidomide-PEG2-OH 能够合成用于靶向蛋白质降解和 PROTAC(蛋白水解靶向嵌合体)技术的分子。
T9384 Pomalidomide-PEG3-OH

1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]amino]-

PROTACs PROTAC
Pomalidomide-PEG3-OH 能够合成用于靶向蛋白质降解和 PROTAC(蛋白水解靶向嵌合体)技术的分子。
T77909 Mirzotamab

Immunology/Inflammation related Immunology/Inflammation
Mirzotamab 是一种靶向 CD276/B7-H3 的 IgG1κ 抗体,是 Mirzotamab clezutoclax 的裸抗,由1320 个氨基酸组成。
T4459 PK11000

DNA Alkylator/Crosslinker DNA Damage/DNA Repair
PK11000 是一种烷化剂,可通过共价半胱氨酸修饰来稳定野生型和突变型p53的 DNA 结合结构域。
T23777 BCI-137

BCI137

Others Others
BCI-137 是 Argonaute 2 配体。它通过靶向 MicroRNA 结合域来发挥作用。
T19925 EcDsbB-IN-9

Others Others
EcDsbB-IN-9 是一种特异性 EcDsbB 抑制剂,靶向革兰氏阴性菌的二硫键形成酶 DsbB。
T5100 DJ-V-159

DJ-V159

GPR; Androgen Receptor Endocrinology/Hormones; GPCR/G Protein
DJ-V-159 (DJ-V159) 是一种G 蛋白偶联受体家族C 组6 A 的激动剂。
T21807 INCA-6

Triptycene-1,4-quinone

Others Others
INCA-6 (Triptycene-1,4-quinone) 是细胞渗透性的 NFAT 抑制剂。INCA-6 通过特异性阻断 NFAT 底物靶向钙调神经磷酸酶位点,有效抑制calcineurin (CN)-NFAT 信号传导。
TNU0022 6-Azauridine

6-Azuridine

Apoptosis Apoptosis
6-Azauridine (6-Azuridine) is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting malignant tumors of the inert lymphatic system and inducing apoptosis.6-Azuridine's anticancer mechanism is dependent on the inhibition of DNA synthesis.
T19826 Rabeprazole

LY307640

Potassium Channel; STAT JAK/STAT signaling; Membrane transporter/Ion channel; Stem Cells
Rabeprazole (LY307640) 是一种 H+/K+-ATPase 抑制剂,通过靶向 STAT3 介导的糖酵解来抑制胃上皮细胞中的细胞增殖,可用于研究胃溃疡。
T9957 LASV inhibitor 3.3

Virus Protease Microbiology/Virology
LASV inhibitor 3.3 是一种针对溶酶体相关膜蛋白 1 (LAMP1) 的拉沙热病毒 (LASV) 抑制剂,LAMP1 是一种在感染期间与 LASV 糖蛋白 (GP) 结合的宿主因子。
T3995 Amcasertib

安卡舍替,BBI503

Stemness kinase Stem Cells
Amcasertib (BBI503) 是一种cancer stemness kinase 抑制剂,抑制Nanog 和其他癌症干细胞通路,具有潜在的抗癌活性。
T38239 2'-Deoxy-2'-fluorouridine

Others Others
2'-Deoxy-2'-fluorouridine 是合成抗流感病毒试剂的中间体。
T9104 TJ191

Apoptosis Apoptosis
TJ191 是一种选择性抗癌试剂,靶向低 TβRIII 表达的恶性T 细胞白血病/淋巴瘤细胞,可研究癌症。

化合物

Cancer-Targeting Compound 1
Cat.No: T13572
Synonym:
Target: Others
Itch-Targeting Compound 1
Cat.No: T10071
Synonym:
Target: Others
Arrhythmias-Targeting Compound 1
Cat.No: T13573
Synonym:
Target: Others
Arrhythmic-Targeting Compound 1
Cat.No: T13900
Synonym:
Target: Others
Neuromuscular-targeting compound 1
Cat.No: T13491
Synonym:
Target: Others
Neurodegenerative Disorder-Targeting Compound 1
Cat.No: T13486
Synonym:
Target: Others
Urinary Incontinence-Targeting Compound 1
Cat.No: T19417
Synonym:
Target: Others
Neuromuscular Disorder-Targeting Compound 1
Cat.No: T10059
Synonym:
Target: Others
TPP-1 hydrochloride
Cat.No: T83724
Synonym: Targeting PD-L1 Peptide
Target:
Soluble Epoxide Hydrolase PROTAC 1a
Cat.No: T83857
Synonym: sEH Proteolysis-targeting Chimera 1a,Soluble Epoxide Hydrolase Proteolysis-targeting Chimera 1a,sEH PROTAC 1a
Target: Others
(Rac)-Neurodegenerative Disorder-Targeting Compound 1
Cat.No: T83527
Synonym:
Target: Others
Targeting the bacterial sliding clamp peptide 46
Cat.No: T76218
Synonym:
Target: Others
Dxd
Cat.No: T11249L
Synonym: Exatecan derivative for ADC,OQM5SD32BQ,UNII-OQM5SD32BQ
Target: Topoisomerase, ADC Cytotoxin
TSPO ligand-2 
Cat.No: T60015
Synonym: Carbonic acid
Target: AUTACs
Brr2-IN-3
Cat.No: T22282
Synonym: Brr2 Inhibitor 9,Brr2 Inhibitor C9
Target: Others
5(6)-Carboxyfluorescein
Cat.No: T18893
Synonym: 5(6)-羧基荧光素,5-(and-6)-Carboxyfluorescein mixed isomers,5(6)-FAM
Target: Others
Chetomin
Cat.No: T6804
Synonym: Chaetomin,NSC289491,BRN0077366
Target: Apoptosis, HSP, HIF
tri-GalNAc-COOH
Cat.No: T39370
Synonym:
Target: LYTACs
ALK kinase inhibitor-1
Cat.No: T6409
Synonym: SAR348830
Target: Others
Dopamine D2 receptor agonist-2
Cat.No: T60075
Synonym: Dopamine D2 Receptor
Target: Dopamine Receptor
NAcM-OPT
Cat.No: T5374
Synonym:
Target: E1/E2/E3 Enzyme, NEDD8
BGB-102
Cat.No: T10531
Synonym: JNJ-26483327
Target: EGFR, VEGFR, FLT, Src
5-Methoxyuridine
Cat.No: TNU0123
Synonym: Mo5U
Target: Apoptosis
Eph inhibitor 2
Cat.No: T5451
Synonym: Ehp-inhibitor-1
Target: Ephrin Receptor
Walrycin B
Cat.No: T1832
Synonym:
Target: Antibacterial, Antibiotic
Ehp-inhibitor-2
Cat.No: T5452
Synonym:
Target: Ephrin Receptor
UNC6934
Cat.No: T9584
Synonym:
Target: Others, Histone Methyltransferase
JCP174
Cat.No: T25549
Synonym: JCP 174,JCP-174
Target: Serine Protease
α-Conotoxin PIA acetate
Cat.No: TP2065L
Synonym:
Target: AChR
Theodrenaline hydrochloride
Cat.No: T13142L
Synonym: Theodrenaline hydrochloride(13460-98-5 Free base)
Target: SARS-CoV
NSC 146109 hydrochloride
Cat.No: T12257
Synonym:
Target: Apoptosis, Others
PCNA-I1
Cat.No: T8955
Synonym:
Target: Others
Panitumumab
Cat.No: T9927
Synonym:
Target: EGFR
CDD3506
Cat.No: T13601
Synonym: 1-TRITYL-1H-IMIDAZOL-4-AMINE
Target: P450
Cephalexin monohydrate
Cat.No: T20022
Synonym: Cephalexin hydrate,Cephacillin hydrate,Cefalexin hydrate
Target: Antibiotic
PROTAC BRD4 ligand-1
Cat.No: T12551
Synonym:
Target: Epigenetic Reader Domain, Ligands for Target Protein for PROTAC
Pomalidomide-PEG2-OH
Cat.No: T9383
Synonym: 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-(2-hydroxyethoxy)ethyl]amino]-
Target: PROTACs
Pomalidomide-PEG3-OH
Cat.No: T9384
Synonym: 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]amino]-
Target: PROTACs
Mirzotamab
Cat.No: T77909
Synonym:
Target: Immunology/Inflammation related
PK11000
Cat.No: T4459
Synonym:
Target: DNA Alkylator/Crosslinker
BCI-137
Cat.No: T23777
Synonym: BCI137
Target: Others
EcDsbB-IN-9
Cat.No: T19925
Synonym:
Target: Others
DJ-V-159
Cat.No: T5100
Synonym: DJ-V159
Target: GPR, Androgen Receptor
INCA-6
Cat.No: T21807
Synonym: Triptycene-1,4-quinone
Target: Others
6-Azauridine
Cat.No: TNU0022
Synonym: 6-Azuridine
Target: Apoptosis
Rabeprazole
Cat.No: T19826
Synonym: LY307640
Target: Potassium Channel, STAT
LASV inhibitor 3.3
Cat.No: T9957
Synonym:
Target: Virus Protease
Amcasertib
Cat.No: T3995
Synonym: 安卡舍替,BBI503
Target: Stemness kinase
2'-Deoxy-2'-fluorouridine
Cat.No: T38239
Synonym:
Target: Others
TJ191
Cat.No: T9104
Synonym:
Target: Apoptosis
Cat. No. Product Name Target Signaling Pathways
T6212 Combretastatin A4

CA4,康普瑞汀,Z)-3,4,5,4',-四甲氧基-3'-羟基二苯乙烯,CRC 87-09

Microtubule Associated Cytoskeletal Signaling
Combretastatin A4 (CA4) 是一种微管靶向剂,可结合 β-tubulin,Kd 值为 0.4 μM。
T5225 Hypotaurine

2-Aminoethanesulfinic acid,亚牛磺酸,2-Aminoethylsulfinic acid

Chloride channel; Endogenous Metabolite Membrane transporter/Ion channel; Metabolism
Hypotaurine (2-Aminoethanesulfinic acid) 是星形胶质细胞中半胱氨酸生物合成的牛磺酸中间体,是甘氨酸受体 (glycine receptor) 的内源性抑制性氨基酸。Hypotaurine 也是抗氧化剂。
T5770 Alisol B

RANKL/RANK NF-κB
Alisol B 是一种具有用于骨科疾病研究潜力的化合物,通过分化破骨细胞发挥其功能。
TN1068 Tricin

Others; CDK Cell Cycle/Checkpoint; Others
Tricin 是米糠中大量存在的一种天然类黄酮。它通过抑制 CDK9 来抑制HCMV 的复制。它通过上调 FAK 靶向 microRNA-7 的表达来抑制 C6 胶质瘤细胞的增殖和侵袭。
T3777 Praeruptorin A

(+)-Praeruptorin A,白花前胡甲素

CaMK; NF-κB Neuroscience; NF-κB
Praeruptorin A ((+)-Praeruptorin A) 是一种白花前胡的主要生物活性成分。它能够抑制 NF-κB 活化,发挥抗炎作用。
TNU0052 Nebularine

9-(beta-D-Ribofuranosyl)-9H-purine

Apoptosis Apoptosis
Nebularine (9-(beta-D-Ribofuranosyl)-9H-purine),是一种嘌呤核苷类似物,具有广谱的抗肿瘤活性,针对惰性淋巴恶性肿瘤并诱导凋亡。Nebularine的抗癌机制依赖于抑制DNA合成。
T36857 Estrone sulfate sodium

雌酮3-硫酸钠,Estrone 3-sulfate (sodium salt),17β-Estrone 3-sulfate

Endogenous Metabolite Metabolism
Estrone sulfate sodium (17β-Estrone 3-sulfate) 是一种主要的循环血浆雌激素,无生物活性,通过类固醇硫酸酯酶(STS) 转化为生物活性雌激素雌酮。
T9715 Aplidine

SARS-CoV; DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
Aplidine 是有效的eEF1A2(KD=80 nM) 靶向的抗癌药物。Aplidine 具有抗病毒活性,抑制SARS-CoV-2的 IC90为 0.88 nM。Aplidine 在多发性骨髓瘤,晚期癌症及 COVID-19 领域有研究的价值。
T6272 Fosbretabulin Disodium

Combretastatin A4 Phosphate,CA 4DP,CA 4P,福他布林,Combretastatin A4 disodium phosphate,Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium

Apoptosis; Microtubule Associated Apoptosis; Cytoskeletal Signaling
Fosbretabulin Disodium (CA 4P) 是一种微管蛋白去稳定剂,是 Combretastatin A4 前药,可选择性靶向内皮细胞,诱导新生肿瘤新血管消退,减少肿瘤血流量并引起中央肿瘤坏死。
TN6551 Tectoruside

Antioxidant oxidation-reduction
Tectoruside 是一种从鸢尾和豹纹百合中提取得到的酚酸糖苷,具有抗诱变和抗氧化活性,通过靶向ROS相关炎症和IRS-1通路来减弱棕榈酸酯诱导的内皮胰岛素抵抗。Tectoruside 可用于研究癌症。
T3752 4-Hydroxybenzyl alcohol

4-Methylolphenol,P-Methylolphenol,对羟基苯甲醇

Apoptosis; Endogenous Metabolite Apoptosis; Metabolism
4-Hydroxybenzyl alcohol (P-Methylolphenol) 是广泛分布于各种植物中的一种酚类天然产物,具有抗炎、抗氧化和抗伤害感受活性。它抑制肿瘤血管生成和生长,有神经保护作用。
TN1308 6-Hydroxyflavanone

Others; Lipoxygenase; COX; GABA Receptor Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience; Others
6-Hydroxyflavanone 是从菖蒲叶中提取分离,通过靶向环氧合酶-2(COX-2),5-脂氧合酶(5-LOX)以及阿片类药物和 GABA-A 受体从而具有抗炎和抗神经性疼痛活性。6-Hydroxyflavanone 在链脲佐菌素诱导的糖尿病神经病变模型中具有抗伤害感受特性。
TJS1779 Protosappanin A

原苏木素A,PTA

NADPH-oxidase; IL Receptor; IκB/IKK; TNF; NF-κB; TLR; ROS; COX; HIV Protease; JAK; NO Synthase; STAT Angiogenesis; Apoptosis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Microbiology/Virology; Neuroscience; NF-κB; Proteases/Proteasome; Stem Cells
Protosappanin A (PTA) 是从苏木中分离得到的免疫抑制成分和主要联苯化合物,通过下调 JAK2和 STAT3的磷酸化,抑制 JAK2/STAT3依赖的炎症通路。
T6S1740 Nardosinone

苷松新酮,甘松新酮

Others Others
Nardosinone 是一个 dbcAMP 和 staurosporine 的神经生成作用增强剂,分离自Nardostachys chinensis 中。Nardosinone 可能成为一种有用的药理学工具,不仅可用于研究神经生长因子 (NGF) 的作用机理,而且可用于研究神经毒性物质的作用机理。
T4S1419 (±)-Praeruptorin A

Praeruptorin A,(±)-白花前胡甲素,白花前胡甲素,(-)-Praeruptorin A

p38 MAPK; Calcium Channel; Akt Cytoskeletal Signaling; MAPK; Membrane transporter/Ion channel; Metabolism; PI3K/Akt/mTOR signaling
(±)-Praeruptorin A 是来自白花前胡的干燥根中的一种主要成分,用于研究伴有厚痰和呼吸困难的咳嗽,非天生性咳嗽和上呼吸道感染。它是顺式-内酯 (CKL) 的二酯化产物,可作为 Ca2+-反流阻滞剂,用于高血压的研究。
T11215 Episilvestrol

Others Others
Episilvestrol is a specific eIF4A-targeting translation inhibitor, with antitumor activity. Episilvestrol is a derivative of silvestrol, isolated from the fruits and twigs of Aglaia silvestris.
TL0017 Aristolactam AIIIa

MAPK; CDK Cell Cycle/Checkpoint; MAPK
Aristolactam AIIIa is a new type of Plk1 inhibitors, targeting the Polo Box domain (PBD), it has anti-tumor activity. Aristolactam IIIa shows inhibition of platelet aggregation induced by collagen or arachidonic acid.
T19557 Sanshool

Others Others
Sanshool is a natural product isolated from Zanthoxylum bungeanum. Sanshool improves UVB-induced skin photodamage by targeting JAK2/STAT3-dependent autophagy.
T10072 2-Hydroxy Ibuprofen

2-羟基布洛芬,(±)-2-Hydroxy Ibuprofen

Others Others
2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1/COX-2 (IC50s: 13 μM/370 μM).
TN3809 Dehydrojuncusol

HCV Protease Microbiology/Virology; Proteases/Proteasome
Dehydrojuncusol, a new inhibitor of hepatitis C virus RNA replication, it inhibits infection of different HCV genotypes by targeting the NS5A protein and is active against resistant HCV variants frequently found in patients with treatment failure.
TN6651 Picrasidine Q

Picrasidine Q has the capacity of anti-cell transformation and anti-cancer, it might be a chemopreventive and chemotherapeutic agent by direct targeting FGFR2 and inhibiting cell proliferation of ESCC cells.
T83518 (S)-O-Methylencecalinol

(S)-O-Methylencecalinol (compound 10),一种从Ageratina grandfolia地上部分分离得到的化合物,目标是钙调素。
T83367 3,5-Diprenyl-4-hydroxyacetophenone

3,5-Diprenyl-4-hydroxyacetophenone(化合物8)是从桔梗地上部分分离出的化合物,具有钙调素靶向性。
T16719 Radicicol

根赤壳菌素,Monorden

HSP Cytoskeletal Signaling; Metabolism
Radicicol is an antifungal antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB. Radicicol is an inhibitor of Hsp90 (IC50: 1 μM). Radicicol binds to the ATPase domain of Hsp90 and prevents maturation of Hsp90 clients,
TN7281 Bequinostatin A

Others Others
Glutathione S-Transferase (GST) π-class inhibitor acts to inhibit a specific class within the GST enzyme family, targeting the π variant. This compound selectively blocks the activity of this enzyme, which plays a critical role in the detoxification of compounds by catalyzing their conjugation with glutathione.
TN1985 Neoprzewaquinone A

ROCK; Pim; STAT Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; JAK/STAT signaling; Stem Cells
Neoprzewaquinone A (NEO) 是 S. miltiorrhiza 的活性成分,通过靶向 PIM1 阻断 ROCK2/STAT3 通路来抑制乳腺癌细胞迁移并促进平滑肌松弛。
T15467 Helenalin

Others Others
Helenalin is a selective inhibitor of transcription factor NF-κB by direct targeting of p65. It is an anti-inflammatory sesquiterpene lactone compound with alkylating activity. Through its ability to target the cysteine sulfhydryl groups in the p65 subunit of NF-κB, helenalin effectively inhibits its DNA binding.
TN4840 Psoromic acid

Others Others
Psoromic acid is a selective and covalent rab-prenylation inhibitor targeting autoinhibited RabGGTase, it shows antibacterial activities against Streptococcus gordonii and Porphyromonas gingivalis, and it is an effective and safe natural drug plausible fo
T79951 Piperkadsin A

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
Piperkadsin A作为一种ROS抑制剂,能够有效地抑制PMA诱导的人多形核中性粒细胞中ROS的生成,其IC50值为4.3 μM。
TN5880 Mesuol

Mesuol has antioxidant activity, it shows very high scavenging activity against DPPH radical; it also has immunomodulatory activity, can potentiate percentage neutrophil adhesion in neutrophil adhesion test in rats and phagocytosis in carbon clearance assay. Mesuol can suppress HIV-1 replication in Jurkat T cells, it inhibits TNFα-induced HIV-1-LTR transcriptional activity by targeting the nuclear factor-κB (NF-κB) pathway.
TL0014 Pinusolide

ERK; p38 MAPK; Calcium Channel; Lipoxygenase; PAFR; Caspase; JNK; AMPK Apoptosis; Chromatin/Epigenetic; GPCR/G Protein; MAPK; Membrane transporter/Ion channel; Metabolism; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Pinusolide is a platelet activating factor ( PAF) antagonist, it may prove of therapeutic value in the treatment of hypotension, it has antileukemic potential, and could be used to treat neurodegenerative diseases. Pinusolide attenuates blockade of insulin signaling by enhancing IRS-1 tyrosine phosphorylation by the activating the AMPK pathway, indicates the targeting of AMPK represents a new therapeutic strategy for hyperglycemia-induced insulin resistance and type 2 diabetes.
TN4605 Myriceric acid B

HIV Protease Microbiology/Virology; Proteases/Proteasome
Myriceric acid B is a potent HIV-1 entry inhibitor targeting gp41 and can serve as a lead compound for developing novel anti-HIV-1 drug. Myriceric acid B scavenges DPPH free radicals with IC50 value of 21.8 uM, it inhibits aromatase activity with IC50 val
TN4263 Isoangustone A

MMP; GSK-3; NF-κB; ROS; Akt; PI3K; CDK; JNK Cell Cycle/Checkpoint; Cytoskeletal Signaling; Immunology/Inflammation; MAPK; NF-κB; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation by targeting PI3K, MKK4, and MKK7 in human melanoma. Isoangustone A dampens mesangial sclerosis associated with inflammation in response to high glucose through hindering TGF-β and NF-κB signaling. Isoangustone A also shows strong ferric reducing activities and effectively scavenged DPPH, ABTS(+), and singlet oxygen radicals.
TMA0984 Cerevisterol

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Cerevisterol 是一种细胞毒性类固醇,提取于Agaricus blazei 子实体,对 DNA 聚合酶 α 的活性具有抑制作用。
TN4213 Hirsutenone

ERK; EGFR; IL Receptor; NF-κB; Akt; PI3K; Antifection; mTOR; p53; Autophagy Angiogenesis; Apoptosis; Autophagy; Cytoskeletal Signaling; Immunology/Inflammation; JAK/STAT signaling; MAPK; Microbiology/Virology; NF-κB; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid peroxidation.Hirsutenone exhibits anti-cancer, and anti-filarial effects, it may exert a preventive effect against microbial endotoxin lipopolysaccharide-induced inflammatory skin diseases through inhibition of ERK pathway-mediated NF-kappaB activation. Hirsutenone attenuates adipogenesis by directly targeting PI3K and ERK during MCE in 3T3-...
T73066 Thielavin B

Others Others
Thielavin B为Thielavin terricola产生的前列腺素生物合成抑制剂。该化合物能有效抑制内过氧物酶介导的前列腺素E2合成,并在静脉注射后显著降低大鼠因角叉菜胶引发的水肿。
T73730 Distamycin A

Others Others
Distamycin A (NSC-82150)为一种寡肽抗生素及小沟结合剂,其结合B型DNA,并倾向于A/T富集区。Distamycin A能调节烯二炔诱导DNA切割位点并促进细胞凋亡。
T73813 Haemanthamine hydrochloride

Others Others
Haemanthamine hydrochloride 是从Amaryllidaceae 植物中分离出来的一种蛇毒碱样生物碱,具有强大的抗癌活性。Haemanthamine hydrochloride 靶向核糖体以在翻译的延长阶段抑制蛋白质的生物合成。Haemanthamine hydrochloride 具有促凋亡,抗氧化剂,抗病毒,抗疟疾和抗惊厥活性。
TN1953 Morusinol

桑根皮醇,桑树醇

ERK; MEK; Autophagy; Ras Autophagy; GPCR/G Protein; MAPK
Morusinol 是从桑树根皮中提取出的类黄酮。 Morusinol 具有抗血小板和抗癌活性,在体内抑制动脉血栓形成,通过诱导自噬、G2/M 细胞周期阻滞、抑制细胞侵袭和迁移以及靶向 Ras/MEK/ERK 通路发挥抗肿瘤活性。
T78465 H-γ-Glu-Gln-OH

γ-Glutamylglutamine,γ-Glu-Gln

Others Others
H-γ-Glu-Gln-OH 是一种水溶性肽类化合物,用于药物结合。该载体特征为高溶解度、药物负载效能、优良生物相容性、低毒性,并能增强抗癌药物对肿瘤的靶向作用及疗效。
T72208 1-Dehydro-[10]-gingerdione

Others Others
1-Dehydro-[10]-gingerdione 通过靶向IKKβ的激活环直接抑制 IKKβ 活性,从而破坏用激动剂刺激的巨噬细胞中 IKKβ 催化的 IκBα 磷酸化。1-Dehydro-[10]-gingerdione 抑制 LPS 诱导的NF-κB 转录活性。1-Dehydro-[10]-gingerdione 具有用于NF-κB 相关炎症和自身免疫性疾病研究的潜力。
T74516 CI-39

Others Others
CI-39 是一种抗病毒天然产物。CI-39 是一种 NNRTI (非核苷类逆转录酶抑制) 抗病毒剂,对野生型HIV 的EC50为 3.40 µM,CC50>30 µM。CI-39 抑制HIV-1RT DNA 聚合酶和核糖核酸酶 H 活性。
T79975 Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside

HBV Microbiology/Virology
Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside(化合物1)是一种具有抗HBV活性的木脂素类化合物。该化合物对HBV表面抗原(HBsAg)的IC50为0.58 mM,而对HBV e抗原(HBeAg)的IC50 > 2.4 mM。其可从八角茴香中提取分离。
T74368 OKI-006

Others Others
OKI-006 是一种有效的、具有口服活性的组蛋白脱乙酰酶 (HDAC) 抑制剂。OKI-006 是天然产物HDAC 抑制剂 largazole 的独特同系物。组蛋白去乙酰化酶 (HDAC) 在表观基因组调控中起关键作用,并且组蛋白乙酰化在许多人类癌症中失调。OKI-006 具有研究癌症疾病的潜力。
TN4838 Pseurotin A

Antifection Microbiology/Virology
Pseurotin A has immunosuppressive activity, it inhibits immunoglobulin E(IgE) production in vitro.It shows a moderate effect against the phytopathogenic bacteria Erwinia carotovora and Pseudomonas syringae, with IC50 values of 220 and 112 microg ml(-1), r
T36436 Spergualin trihydrochloride

Others Others
Spergualin trihydrochloride is a natural product that first identified as an antibiotic from culture filtrates of Bacillus laterosporus BMG162-aF2[1]. Spergualin trihydrochloride derivatives likely acts as Hsp70 modulators[1]. [1]. Srikanth Patury, et al. Pharmacological Targeting of the Hsp70 Chaperone. Curr Top Med Chem. 2009;9(15):1337-51.
T72803 Norartocarpetin

Others Others
Norartocarpetin 是一种酪氨酸酶抑制剂。Norartocarpetin 具有较强的酪氨酸酶抑制活性,其抑制活性 IC50值为 0.47 μM。Norartocarpetin 作为一种抗褐变剂可用于食品体系的研究。Norartocarpetin 对肺癌细胞 (NCI-H460) 也具有显著的抗癌活性,其 IC50值为 22 μM。Norartocarpetin 的抗增殖作用是通过靶向 Ras/Raf/MAPK 信号通路、线粒体介导的细胞凋亡、S 期细胞周期阻滞和抑制细胞迁移和侵袭实现的。
TN3364 Agrimonolide

Apoptosis; Dehydrogenase; p38 MAPK; ROS; JAK Angiogenesis; Apoptosis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; MAPK; Metabolism; Stem Cells
Agrimonolide 是一种来自异香豆素的化合物,主要存在于草药Agrimonia pilosa Ledeb 中,具有显著的生物活性。Agrimonolide 通过抑制脂多糖(LPS)诱导的JAK-STATs 和p38 MAPKs 信号通路的激活而发挥抗炎作用。Agrimonolide 及其衍生物去甲阿戈莫内德已显示出能够有效提高肝细胞中胰岛素介导的糖原水平,可能在调节胰岛素抵抗的HepG2细胞中发挥关键作用。Agrimonolide 通过靶向卵巢癌细胞中的SCD1,对癌症的进展和诱导细胞死亡和凋亡表现出抑制作用。特别是,Agrimonolide 对A2780和SKOV-3细胞的增殖、迁移和侵袭表现出剂量依赖性的抑制,同时促进细胞凋亡。该化合物还被发现能诱导铁介导的细胞死亡,同时增加活性氧(ROS)和总铁的水平。Agrimonolide 很容易穿过血脑屏障,表明其在神经系统疾病的治疗应用方面具有潜力。

天然产物

Combretastatin A4
Cat.No: T6212
Synonym: CA4,康普瑞汀,Z)-3,4,5,4',-四甲氧基-3'-羟基二苯乙烯,CRC 87-09
Target: Microtubule Associated
Hypotaurine
Cat.No: T5225
Synonym: 2-Aminoethanesulfinic acid,亚牛磺酸,2-Aminoethylsulfinic acid
Target: Chloride channel, Endogenous Metabolite
Alisol B
Cat.No: T5770
Synonym:
Target: RANKL/RANK
Tricin
Cat.No: TN1068
Synonym:
Target: Others, CDK
Praeruptorin A
Cat.No: T3777
Synonym: (+)-Praeruptorin A,白花前胡甲素
Target: CaMK, NF-κB
Nebularine
Cat.No: TNU0052
Synonym: 9-(beta-D-Ribofuranosyl)-9H-purine
Target: Apoptosis
Estrone sulfate sodium
Cat.No: T36857
Synonym: 雌酮3-硫酸钠,Estrone 3-sulfate (sodium salt),17β-Estrone 3-sulfate
Target: Endogenous Metabolite
Aplidine
Cat.No: T9715
Synonym:
Target: SARS-CoV, DNA/RNA Synthesis
Fosbretabulin Disodium
Cat.No: T6272
Synonym: Combretastatin A4 Phosphate,CA 4DP,CA 4P,福他布林,Combretastatin A4 disodium phosphate,Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium
Target: Apoptosis, Microtubule Associated
Tectoruside
Cat.No: TN6551
Synonym:
Target: Antioxidant
4-Hydroxybenzyl alcohol
Cat.No: T3752
Synonym: 4-Methylolphenol,P-Methylolphenol,对羟基苯甲醇
Target: Apoptosis, Endogenous Metabolite
6-Hydroxyflavanone
Cat.No: TN1308
Synonym:
Target: Others, Lipoxygenase, COX, GABA Receptor
Protosappanin A
Cat.No: TJS1779
Synonym: 原苏木素A,PTA
Target: NADPH-oxidase, IL Receptor, IκB/IKK, TNF, NF-κB, TLR, ROS, COX, HIV Protease, JAK, NO Synthase, STAT
Nardosinone
Cat.No: T6S1740
Synonym: 苷松新酮,甘松新酮
Target: Others
(±)-Praeruptorin A
Cat.No: T4S1419
Synonym: Praeruptorin A,(±)-白花前胡甲素,白花前胡甲素,(-)-Praeruptorin A
Target: p38 MAPK, Calcium Channel, Akt
Episilvestrol
Cat.No: T11215
Synonym:
Target: Others
Aristolactam AIIIa
Cat.No: TL0017
Synonym:
Target: MAPK, CDK
Sanshool
Cat.No: T19557
Synonym:
Target: Others
2-Hydroxy Ibuprofen
Cat.No: T10072
Synonym: 2-羟基布洛芬,(±)-2-Hydroxy Ibuprofen
Target: Others
Dehydrojuncusol
Cat.No: TN3809
Synonym:
Target: HCV Protease
Picrasidine Q
Cat.No: TN6651
Synonym:
Target:
(S)-O-Methylencecalinol
Cat.No: T83518
Synonym:
Target:
3,5-Diprenyl-4-hydroxyacetophenone
Cat.No: T83367
Synonym:
Target:
Radicicol
Cat.No: T16719
Synonym: 根赤壳菌素,Monorden
Target: HSP
Bequinostatin A
Cat.No: TN7281
Synonym:
Target: Others
Neoprzewaquinone A
Cat.No: TN1985
Synonym:
Target: ROCK, Pim, STAT
Helenalin
Cat.No: T15467
Synonym:
Target: Others
Psoromic acid
Cat.No: TN4840
Synonym:
Target: Others
Piperkadsin A
Cat.No: T79951
Synonym:
Target: Reactive Oxygen Species
Mesuol
Cat.No: TN5880
Synonym:
Target:
Pinusolide
Cat.No: TL0014
Synonym:
Target: ERK, p38 MAPK, Calcium Channel, Lipoxygenase, PAFR, Caspase, JNK, AMPK
Myriceric acid B
Cat.No: TN4605
Synonym:
Target: HIV Protease
Isoangustone A
Cat.No: TN4263
Synonym:
Target: MMP, GSK-3, NF-κB, ROS, Akt, PI3K, CDK, JNK
Cerevisterol
Cat.No: TMA0984
Synonym:
Target: DNA/RNA Synthesis
Hirsutenone
Cat.No: TN4213
Synonym:
Target: ERK, EGFR, IL Receptor, NF-κB, Akt, PI3K, Antifection, mTOR, p53, Autophagy
Thielavin B
Cat.No: T73066
Synonym:
Target: Others
Distamycin A
Cat.No: T73730
Synonym:
Target: Others
Haemanthamine hydrochloride
Cat.No: T73813
Synonym:
Target: Others
Morusinol
Cat.No: TN1953
Synonym: 桑根皮醇,桑树醇
Target: ERK, MEK, Autophagy, Ras
H-γ-Glu-Gln-OH
Cat.No: T78465
Synonym: γ-Glutamylglutamine,γ-Glu-Gln
Target: Others
1-Dehydro-[10]-gingerdione
Cat.No: T72208
Synonym:
Target: Others
CI-39
Cat.No: T74516
Synonym:
Target: Others
Dihydrodehydrodiconiferyl alcohol 9-O-α-L-rhamnopyranoside
Cat.No: T79975
Synonym:
Target: HBV
OKI-006
Cat.No: T74368
Synonym:
Target: Others
Pseurotin A
Cat.No: TN4838
Synonym:
Target: Antifection
Spergualin trihydrochloride
Cat.No: T36436
Synonym:
Target: Others
Norartocarpetin
Cat.No: T72803
Synonym:
Target: Others
Agrimonolide
Cat.No: TN3364
Synonym:
Target: Apoptosis, Dehydrogenase, p38 MAPK, ROS, JAK
Cat. No. Product Name Species Expression System
TMPH-02826 PEX5 Protein, Mouse, Recombinant (His & Myc)

PTS1-BP,Peroxisomal C-terminal targeting signal imp...

Mouse E. coli
Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
TMPH-02723 KPNB1 Protein, Mouse, Recombinant (His)

SCG,Nuclear factor p97,Kpnb1,Karyopherin subunit beta-1,Pore...

Mouse E. coli
KPNB1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 101.2 kDa and the accession number is P70168.
TMPJ-01120 KPNB1 Protein, Human, Recombinant (His)

Nuclear factor p97,Importin subunit β-1,NTF97,Karyopherin su...

Human E. coli
Importin subunit beta-1(KPNB1) is a member of the importin beta family. KPNB1 contains 1 importin N-terminal domain and 19 HEAT repeats. It is involved in nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. Its functions in nuclear protein import, either in association with an adapter protein, like an importin-alpha subunit, which binds to nuclear localization signals (NLS) in cargo substrates, or by ac...
TMPK-00925 Noggin/NOG Protein, Mouse, Recombinant

NOG,SYM1,SYNS1,Noggin

Mouse HEK293 Cells
Noggin is an antagonist of bone morphogenetic proteins (BMP), being indispensable for certain developmental events.Noggin expression positively correlated with EGFR expression in both GC cell line models and The Cancer Genome Atlas human GC cohort. Targeting EGFR and its downstream pathways diminished cell proliferation which was promoted by Noggin. Noggin promotes the proliferation of GC cells by upregulating EGFR and enhancing a vicious circle formed by β‑catenin, EGFR, ERK and Akt. Noggin/NOG...
TMPY-03958 TGF alpha Protein, Human, Recombinant

transforming growth factor α,转化生长因子,transforming growth fact...

Human E. coli
The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared to adjacent normal tissue and high TGFA gene expression strongly correlated with poor survival in patients with lung adenocarcinoma, and miR-374a suppresses lung adenocarcinoma cell proliferation and invasion via targeting TGFA gene expression. Transforming growth factor alpha (...
TMPY-03407 NQO1 Protein, Human, Recombinant (His)

NAD(P)H dehydrogenase, quinone 1,NMORI,DIA4,QR1,NMOR1,DTD,DH...

Human E. coli
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered ex...
TMPY-02481 ACOX1 Protein, Human, Recombinant (His)

PALMCOX,ACOX,SCOX,acyl-CoA oxidase 1, palmitoyl

Human Baculovirus Insect Cells
Peroxisomal acyl-coenzyme A oxidase 1(ACOX1 or AOX) is the first enzyme of the fatty acid beta-oxidation pathway and belongs to the Acyl-CoA oxidase family. Human liver peroxisomes contain two acyl-CoA oxidases, namely, palmitoyl-CoA oxidase (ACOX1/AOX) and a branched chain acyl-CoA oxidase. The palmitoyl-CoA oxidase (ACOX1/AOX) oxidizes the CoA esters of straight chain fatty acids and prostaglandins and donates electrons directly to molecular oxygen, thereby producing H2O2. Human ACOX1/AOX is a...
TMPY-04830 GAS6 Protein, Mouse, Recombinant (His)

growth arrest-specific 6,Gas-6

Mouse HEK293 Cells
The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin K-dependent protein, plays a role in the survival, proliferation, migration, differentiation, adhesion, and apoptosis of cells. The growth arrest-specific 6 (GAS6) has been implicated in systemic inflammation and coagulation. Growth arrest-specific 6 (GAS6), plays a role in tumor...
TMPH-01948 PPP1R3G Protein, Human, Recombinant (His & Myc)

PPP1R3G,Protein phosphatase 1 regulatory subunit 3G

Human E. coli
Glycogen-targeting subunit for protein phosphatase 1 (PP1). Involved in the regulation of hepatic glycogenesis in a manner coupled to the fasting-feeding cycle and distinct from other glycogen-targeting subunits. PPP1R3G Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 45.5 kDa and the accession number is B7ZBB8.
TMPK-00809 CD37 Protein, Human, Recombinant (His)

Tspan-26,GP52-40,Tetraspanin-26,MGC120234,CD37 molecule,CD37

Human HEK293 Cells
CD37 is a tetraspanin expressed prominently on the surface of B cells. It is an attractive molecular target exploited in the immunotherapy of B cell-derived lymphomas and leukemia. Currently, several monoclonal antibodies targeting CD37 as well as chimeric antigen receptor-based immunotherapies are being developed and investigated in clinical trials. Given the unique role of CD37 in the biology of B cells, it seems that CD37 constitutes more than a docking point for monoclonal antibodies, and ta...
TMPH-03324 LIMPII/SR-B2 Protein, Rat, Recombinant (His & Myc)

85 kDa lysosomal membrane sialoglycoprotein,Scarb2,CD36 anti...

Rat E. coli
Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting. LIMPII/SR-B2 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 53.7 kDa and the accession number is P27615.
TMPH-03521 MecA Protein, S. aureus, Recombinant (His & SUMO)

Adapter protein MecA,mecA

Staphylococcus aureus E. coli
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. MecA Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.3 kDa and the accession number is P60186.
TMPH-00823 Gamma-hordein-3 Protein, Hordeum vulgare, Recombinant (His & Myc)

Gamma-hordein-3

Hordeum vulgare E. coli
Has a role in the transport and targeting of prolamins to the vacuole of developing barley endosperm. Gamma-hordein-3 Protein, Hordeum vulgare, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 40.6 kDa and the accession number is P80198.
TMPK-00994 FNDC1 Protein, Human, Recombinant (His)

FNDC2,MEL4B3,KIAA1866

Human E. coli
Fibronectin type III domain‑containing protein 1 (FNDC1) is a protein that contains a major component of the structural domain of fibronectin.FNDC1 was highly upregulated and acted as an oncogene in BC. Therefore, targeting FNDC1 may be a potential strategy for the treatment of BC.
TMPH-03380 Synaptophysin/SYP Protein, Rat, Recombinant (His)

Major synaptic vesicle protein p38,Synaptophysin,Syp

Rat E. coli
Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity. Synaptophysin/SYP Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 34.8 kDa and the accession number is P07825.
TMPH-02330 Zyxin Protein, Human, Recombinant (His)

Zyxin-2,ZYX,Zyxin

Human HEK293 Cells
Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression.
TMPH-00694 LolA Protein, E. coli O9:H4, Recombinant (His)

Outer-membrane lipoprotein carrier protein,lolA

E. coli P. pastoris (Yeast)
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
TMPK-01519 HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)

MHC,FETA,AFP,Alpha-feto,AFPD,Alpha-1-fetoprotein,HPAFP,Alpha...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01520 HLA-A*02:01&B2M&AFP (PLFQVPEPV) Tetramer Protein, Human, MHC (His & Avi)

Alpha-1-fetoprotein,AFP,HPAFP,FETA,AFPD,MHC,Alpha-fetoprotei...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01417 HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

Alpha-1-fetoprotein,HPAFP,AFPD,AFP,Alpha-feto,MHC,FETA,Alpha...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-00001 CD24 Protein-VLP, Human, Recombinant

CD24A,MGC75043,FLJ43543,CD 24,FLJ22950,CD24 molecule

Human HEK293 Cells
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein-VLP, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 5.0 kDa and the accession number is P25063-1.
TMPK-01482 HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)

MHC,AFPD,Alpha-fetoprotein,FETA,Alpha-1-fetoprotein,AFP,HPAF...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01477 HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated

HPAFP,FETA,Alpha-1-fetoprotein,AFPD,AFP,Alpha-feto,MHC,Alpha...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01484 HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)

HPAFP,FETA,AFP,AFPD,Alpha-1-fetoprotein,MHC,Alpha-fetoprotei...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01483 HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated

AFPD,AFP,Alpha-fetoprotein,HPAFP,MHC,FETA,Alpha-1-fetoprotei...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01515 HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)

HPAFP,Alpha-fetoprotein,MHC,FETA,Alpha-feto,Alpha-1-fetoprot...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-00471 PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated

MGC2463,MGC104322,LPD,C7orf15,ALS2CR18,PREL2,ALS2CR9,RMO1,PR...

Mouse HEK293 Cells
Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth. PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 42.7 kDa and the accession number is ...
TMPK-00470 PVRIG Protein, Mouse, Recombinant (hFc & Avi)

PREL-2,RMO1,MGC2463,C7orf15,MGC104322,PREL2,PVRIG,LPD,MGC138...

Mouse HEK293 Cells
Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth. PVRIG Protein, Mouse, Recombinant (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 42.70 kDa and the accession number is A0A1B0GS01.
TMPK-00004 CD24 Protein, Human, Recombinant (GST)

CD 24,CD24 molecule,FLJ22950,FLJ43543,CD24A,MGC75043

Human E. coli
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 31.6 kDa and the accession number is P25063.
TMPK-01001 RNF43 Protein, Mouse, Recombinant (hFc)

Rnf43,RING finger protein 43,RING-type E3 ubiquitin transfer...

Mouse HEK293 Cells
RNF43 (E3 ubiquitin-protein ligase RNF43 or RING-type E3 ubiquitin transferase RNF43) functions as a tumor suppressor, by exerting a predominant negative feedback mechanism in the Wnt/β-catenin signaling pathway. RNF43 inhibits Wnt/beta-catenin signaling by ubiquitinating Frizzled receptor and targeting it to the lysosomal pathway for degradation.
TMPH-01677 MBD2 Protein, Human, Recombinant (His & KSI)

Methyl-CpG-binding domain protein 2,Methyl-CpG-binding prote...

Human E. coli
Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.
TMPH-02111 SRP72 Protein, Human, Recombinant (GST)

SRP72,Signal recognition particle 72 kDa protein,Signal reco...

Human E. coli
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function. SRP72 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 101.1 kDa and the accession numb...
TMPK-00674 CD24 Protein, Cynomolgus, Recombinant (hFc)

FLJ22950,CD 24,MGC75043,FLJ43543,CD24A,CD24 molecule

Cynomolgus HEK293 Cells
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 30.2 kDa and the accession number is I7GKK1-1.
TMPK-01081 Glypican 2/GPC2 Protein, Mouse, Recombinant (His)

Cerebroglycan,2410016G05Rik,GPC2,Glypican-2

Mouse HEK293 Cells
Glypicans can function as coreceptors for multiple signaling molecules known for regulating cell growth, motility, and differentiation. Some members of the glypican family, including glypican 2 (GPC2) and glypican 3 (GPC3), are expressed in childhood cancers and liver cancers, respectively. Antibody-based therapies targeting glypicans are being investigated in preclinical and clinical studies, with the goal of treating solid tumors that do not respond to standard therapies.
TMPK-01521 HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi)

MHC,Alpha-feto,AFPD,Alpha-1-fetoprotein,Alpha-fetoprotein,FE...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01436 HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

Alpha-1-fetoprotein,FETA,MHC,Alpha-feto,AFPD,Alpha-fetoprote...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01478 HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi), Biotinylated

AFP,FETA,Alpha-feto,HPAFP,Alpha-1-fetoprotein,MHC,Alpha-feto...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPH-01272 TRIM9 Protein, Human, Recombinant (His & SUMO)

RING finger protein 91,RING-type E3 ubiquitin transferase TR...

Human E. coli
E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions and may also participate in the formation or breakdown of abnormal inclusions in neurodegenerative disorders. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation.
TMPK-00104 HMGB1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

HMG3,HMG-1,HMGB1,SBP-1,HMG1

Human HEK293 Cells
High-mobility group box 1 (HMGB1) is a ubiquitous nuclear protein that promotes inflammation when released extracellularly after cellular activation, stress, damage or death. HMGB1 operates as one of the most intriguing molecules in inflammatory disorders via recently elucidated signal and molecular transport mechanisms. Treatments based on antagonists specifically targeting extracellular HMGB1 have generated encouraging results in a wide number of experimental models of infectious and sterile i...
TMPK-01318 CD24 Protein-VLP, Cynomolgus, Recombinant

MGC75043,CD 24,FLJ43543,FLJ22950,CD24 molecule,CD24A

Cynomolgus HEK293 Cells
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein-VLP, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 3.8 kDa and the accession number is XP_015304503.1.
TMPK-01298 BST2 Protein, Cynomolgus, Recombinant (His)

HM1.24 antigen,PDCA-1,BST2,TETHERIN,BST-2,NPC-A-7,CD317

Cynomolgus HEK293 Cells
Interferon-induced BST2 (bone marrow stromal cell antigen 2) inhibits viral replication by tethering enveloped virions to the cell surface to restrict viral release and by inducing the NFKB-dependent antiviral immune response. BST2 expression was significantly increased during porcine epidemic diarrhea virus (PEDV) infection of Vero cells by IRF1 targeting its promoter. Both the BST2 and N protein interacted with the E3 ubiquitin ligase MARCHF8/MARCH8 and the cargo receptor.
TMPK-00675 CD24 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated

MGC75043,FLJ43543,CD24 molecule,FLJ22950,CD 24,CD24A

Cynomolgus HEK293 Cells
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 30.2 kDa...
TMPK-00006 CD24 Protein (Primary Amine Labeling), Human, Recombinant (mFc), Biotinylated

CD 24,CD24A,FLJ43543,CD24 molecule,MGC75043,FLJ22950

Human HEK293 Cells
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein (Primary Amine Labeling), Human, Recombinant (mFc), Biotinylated is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 29.5 kDa and ...
TMPK-01334 EMMPRIN/CD147 Protein, Canine, Recombinant (His)

Basigin,BSG,M6,OK,5F7,TCSF,CD147

Canine HEK293 Cells
CD147, also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulation of extracellular matrix (ECM) remodeling during physiological and pathological processes including wound healing, inflammatory diseases, and cancer. CD147 is a diagnostic and therapeutic target in cancer and inflammatory diseases, either directly or indirectly, by targeting CD147 partners.
TMPH-01595 KMO Protein, Human, Recombinant (His)

Kynurenine 3-monooxygenase,KMO,Kynurenine 3-hydroxylase

Human E. coli
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract (Probable).
TMPK-00002 CD24 Protein, Human, Recombinant (His & Avi)

MGC75043,FLJ22950,CD 24,FLJ43543,CD24A,CD24 molecule

Human HEK293 Cells
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 6.5 kDa and the accession number is P25063...
TMPK-00772 IL-5 Protein, Mouse, Recombinant (His & Avi), Biotinylated

白细胞介素,T-cell replacing factor,IL-5,Interleukin-5,EDF,TRF,白介素

Mouse HEK293 Cells
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the key immune effector cells such as eosinophilic asthma (EA), hypereosinophilic syndrome (HES), eosinophilic esophagitis (EE), and eosinophilic granulomatosis with polyangiitis (EGPA). IL-5 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells ...
TMPK-00021 IL-5 Protein, Human, Recombinant (His & Avi)

Interleukin-5,TRF,IL-5,T-cell replacing factor,白细胞介素,EDF,白介素

Human HEK293 Cells
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the key immune effector cells such as eosinophilic asthma (EA), hypereosinophilic syndrome (HES), eosinophilic esophagitis (EE), and eosinophilic granulomatosis with polyangiitis (EGPA). IL-5 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi...
TMPK-00771 IL-5 Protein, Mouse, Recombinant (His & Avi)

白介素,Interleukin-5,EDF,TRF,IL-5,白细胞介素,T-cell replacing factor

Mouse HEK293 Cells
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the key immune effector cells such as eosinophilic asthma (EA), hypereosinophilic syndrome (HES), eosinophilic esophagitis (EE), and eosinophilic granulomatosis with polyangiitis (EGPA). IL-5 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi...
TMPK-00753 LY6G6D Protein, Human, Recombinant (His)

C6orf23,Ly6-D,NG25,G6D,Protein Ly6-D,MEGT1

Human HEK293 Cells
LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utilized to potently re-direct and activate cytotoxic T-cells to lyse LY6G6D expressing CRC using a TcE. This effect can be spread to target negative neighboring tumor cells, potentially leading to improved therapeutic efficacy. LY6G6D Protein, Human, Recombinant (His) is expressed in ...
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重组蛋白

PEX5 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02826
Species: Mouse
Expression System: E. coli
KPNB1 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02723
Species: Mouse
Expression System: E. coli
KPNB1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01120
Species: Human
Expression System: E. coli
Noggin/NOG Protein, Mouse, Recombinant
Cat.No: TMPK-00925
Species: Mouse
Expression System: HEK293 Cells
TGF alpha Protein, Human, Recombinant
Cat.No: TMPY-03958
Species: Human
Expression System: E. coli
NQO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03407
Species: Human
Expression System: E. coli
ACOX1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02481
Species: Human
Expression System: Baculovirus Insect Cells
GAS6 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04830
Species: Mouse
Expression System: HEK293 Cells
PPP1R3G Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01948
Species: Human
Expression System: E. coli
CD37 Protein, Human, Recombinant (His)
Cat.No: TMPK-00809
Species: Human
Expression System: HEK293 Cells
LIMPII/SR-B2 Protein, Rat, Recombinant (His & Myc)
Cat.No: TMPH-03324
Species: Rat
Expression System: E. coli
MecA Protein, S. aureus, Recombinant (His & SUMO)
Cat.No: TMPH-03521
Species: Staphylococcus aureus
Expression System: E. coli
Gamma-hordein-3 Protein, Hordeum vulgare, Recombinant (His & Myc)
Cat.No: TMPH-00823
Species: Hordeum vulgare
Expression System: E. coli
FNDC1 Protein, Human, Recombinant (His)
Cat.No: TMPK-00994
Species: Human
Expression System: E. coli
Synaptophysin/SYP Protein, Rat, Recombinant (His)
Cat.No: TMPH-03380
Species: Rat
Expression System: E. coli
Zyxin Protein, Human, Recombinant (His)
Cat.No: TMPH-02330
Species: Human
Expression System: HEK293 Cells
LolA Protein, E. coli O9:H4, Recombinant (His)
Cat.No: TMPH-00694
Species: E. coli
Expression System: P. pastoris (Yeast)
HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01519
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&AFP (PLFQVPEPV) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01520
Species: Human
Expression System: HEK293 Cells
HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
Cat.No: TMPK-01417
Species: Human
Expression System: HEK293 Cells
CD24 Protein-VLP, Human, Recombinant
Cat.No: TMPK-00001
Species: Human
Expression System: HEK293 Cells
HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01482
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01477
Species: Human
Expression System: HEK293 Cells
HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01484
Species: Human
Expression System: HEK293 Cells
HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01483
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01515
Species: Human
Expression System: HEK293 Cells
PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPK-00471
Species: Mouse
Expression System: HEK293 Cells
PVRIG Protein, Mouse, Recombinant (hFc & Avi)
Cat.No: TMPK-00470
Species: Mouse
Expression System: HEK293 Cells
CD24 Protein, Human, Recombinant (GST)
Cat.No: TMPK-00004
Species: Human
Expression System: E. coli
RNF43 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-01001
Species: Mouse
Expression System: HEK293 Cells
MBD2 Protein, Human, Recombinant (His & KSI)
Cat.No: TMPH-01677
Species: Human
Expression System: E. coli
SRP72 Protein, Human, Recombinant (GST)
Cat.No: TMPH-02111
Species: Human
Expression System: E. coli
CD24 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPK-00674
Species: Cynomolgus
Expression System: HEK293 Cells
Glypican 2/GPC2 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01081
Species: Mouse
Expression System: HEK293 Cells
HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01521
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
Cat.No: TMPK-01436
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01478
Species: Human
Expression System: HEK293 Cells
TRIM9 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01272
Species: Human
Expression System: E. coli
HMGB1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
Cat.No: TMPK-00104
Species: Human
Expression System: HEK293 Cells
CD24 Protein-VLP, Cynomolgus, Recombinant
Cat.No: TMPK-01318
Species: Cynomolgus
Expression System: HEK293 Cells
BST2 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01298
Species: Cynomolgus
Expression System: HEK293 Cells
CD24 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated
Cat.No: TMPK-00675
Species: Cynomolgus
Expression System: HEK293 Cells
CD24 Protein (Primary Amine Labeling), Human, Recombinant (mFc), Biotinylated
Cat.No: TMPK-00006
Species: Human
Expression System: HEK293 Cells
EMMPRIN/CD147 Protein, Canine, Recombinant (His)
Cat.No: TMPK-01334
Species: Canine
Expression System: HEK293 Cells
KMO Protein, Human, Recombinant (His)
Cat.No: TMPH-01595
Species: Human
Expression System: E. coli
CD24 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00002
Species: Human
Expression System: HEK293 Cells
IL-5 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00772
Species: Mouse
Expression System: HEK293 Cells
IL-5 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00021
Species: Human
Expression System: HEK293 Cells
IL-5 Protein, Mouse, Recombinant (His & Avi)
Cat.No: TMPK-00771
Species: Mouse
Expression System: HEK293 Cells
LY6G6D Protein, Human, Recombinant (His)
Cat.No: TMPK-00753
Species: Human
Expression System: HEK293 Cells
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Cat. No. Product Name Target Signaling Pathways
TMID-0058 Glycocholic acid-d4

Glycocholic acid-d4 是 Glycocholic acid 的氘代化合物。Glycocholic acid 的 CAS 号为 475-31-0。Glycocholic acid 是一种胆汁酸,具有抗肿瘤活性,能够靶向作用于耐药泵和非耐药泵通路。
T73820 Bosentan-d4

Bosentan-d4 是 Bosentan 的氘代物。Bosentan 是一种有效的endothelin-1 (ET)拮抗剂,在人的 SMC 细胞中,作用于ETA 和ETB 受体,Ki 值分别为 4.7 nM 和 95 nM。
TMIH-0091 AOH-d3

AOH-d3 是 AOH 的氘代化合物。AOH 的 CAS 号为 2089314-64-5。AOH1996 是一种具有口服活性的复制体组分 PCNA (增殖细胞核抗原) 配体,靶向转录-复制冲突 (TRC)。AOH1996 可干扰 PCNA 与其结合蛋白的相互作用,导致 DNA 复制应激,诱导细胞凋亡 (apoptosis)。AOH1996 通过稳定 PCNA 和 RNA 聚合酶 II 的相互作用从而导致蛋白酶体依赖的 rpb1 降解和致命的 DNA 损伤。AOH1996 与 DNA 损伤剂具有协同作用,可抑制肿瘤细胞生长。
TMIH-0025 13C-d3-AOH1996

13C-d3-AOH1996 是 AOH1996 的 13C 和氘代化合物。AOH1996 的 CAS 号为 2089314-64-5。AOH1996 是一种具有口服活性的复制体组分 PCNA (增殖细胞核抗原) 配体,靶向转录-复制冲突 (TRC)。AOH1996 可干扰 PCNA 与其结合蛋白的相互作用,导致 DNA 复制应激,诱导细胞凋亡 (apoptosis)。AOH1996 通过稳定 PCNA 和 RNA 聚合酶 II 的相互作用从而导致蛋白酶体依赖的 rpb1 降解和致命的 DNA 损伤。AOH1996 与 DNA 损伤剂具有协同作用,可抑制肿瘤细胞生长。
T35789 Palmitic acid-1-13C

Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.1 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.2 Palmitic acid is involved in the acylation of proteins to anchor membrane-bound proteins to the lipid bilayer.2,3,4,5,6 |1. Santos, M.J., López-Jurado, M., Llopis, J., et a...
T35791 Palmitic acid-13C

Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid-13C contains 13C at the C2 position and has been used in the study of free fatty acid incorporation into phospholipid fatty acids in soil microbes.1 Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.2 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.3 Palmitic ...

同位素标记化合物

Glycocholic acid-d4
Cat.No: TMID-0058
Synonym:
Target:
Bosentan-d4
Cat.No: T73820
Synonym:
Target:
AOH-d3
Cat.No: TMIH-0091
Synonym:
Target:
13C-d3-AOH1996
Cat.No: TMIH-0025
Synonym:
Target:
Palmitic acid-1-13C
Cat.No: T35789
Synonym:
Target:
Palmitic acid-13C
Cat.No: T35791
Synonym:
Target:
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