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Anti-IL7 Monoclonal Antibody

产品编号 TMAZ-0206
别名 Interleukin-7

Anti-IL7 Monoclonal Antibody is a rabbit antibody targeting IL7. Anti-IL7 Monoclonal Antibody can be used in ELISA, FACS.

Anti-IL7 Monoclonal Antibody

Anti-IL7 Monoclonal Antibody

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产品编号 TMAZ-0206 别名 Interleukin-7

Anti-IL7 Monoclonal Antibody is a rabbit antibody targeting IL7. Anti-IL7 Monoclonal Antibody can be used in ELISA, FACS.

规格价格库存数量
25 μg¥ 350.9¥ 6057日内发货
50 μg¥ 420.5¥ 7257日内发货
100 μg¥ 588.7¥ 1,0157日内发货
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产品介绍

生物活性
产品描述
Anti-IL7 Monoclonal Antibody is a rabbit antibody targeting IL7. Anti-IL7 Monoclonal Antibody can be used in ELISA, FACS.
别名Interleukin-7
Ig Type
Rabbit monoclonal IgG
交叉反应
Human
验证活性
Flow cytometry analysis of IL7 overexpressed 490F cells with TMAZ-0206, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
应用
ELISA, FACS
推荐剂量
0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Secreted
构建方式This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of IL7 protein.
纯化方式Protein A Affinity Purified
性状Liquid
缓冲液0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin.
纯度> 95% as determined by SDS-PAGE.
研究背景Hematopoietic cytokine that plays an essential role in the development, expansion, and survival of naive and memory T-cells and B-cells thereby regulating the number of mature lymphocytes and maintaining lymphoid homeostasis (PubMed: 25870237, PubMed: 7527823). Mechanistically, exerts its biological effects through a receptor composed of IL7RA subunit and the cytokine receptor common subunit gamma/CSF2RG (PubMed: 8128231). Binding to the receptor leads to activation of various kinases including JAK1 or JAK3 depending on the cell type and subsequently propagation of signals through activation of several downstream signaling pathways including the PI3K/Akt/mTOR or the JAK-STAT5 (PubMed: 18523275, PubMed: 20974963)
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Biotin/APC/PE/AF488/AF555/AF647
可提供抗体种类
1
抗原信息
免疫原
IL7
抗原种属
Human
基因ID
3574
Uniprot ID
研究领域
Drug Target
化学信息
分子量150 kDa
存储&运输
储存方式For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze.
运输方式For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice.

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