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Episilvestrol is a specific eIF4A-targeting translation inhibitor, with antitumor activity. Episilvestrol is a derivative of silvestrol, isolated from the fruits and twigs of Aglaia silvestris.
Episilvestrol is a specific eIF4A-targeting translation inhibitor, with antitumor activity. Episilvestrol is a derivative of silvestrol, isolated from the fruits and twigs of Aglaia silvestris.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 8,230 | 期货 |
产品描述 | Episilvestrol is a specific eIF4A-targeting translation inhibitor, with antitumor activity. Episilvestrol is a derivative of silvestrol, isolated from the fruits and twigs of Aglaia silvestris. |
体外活性 | Episilvestrol is cytotoxic activity against several human cancer cell lines, such as Lu1, LNCaP, MCF-7 and HUVEC cells, with ED50s of 3.8, 3.8, 5.5 and 15.3 nM, respectively.Episilvestrol is a specific eIF4A-targeting translation inhibitor, with antitumor activity.?Episilvestrol also suppresses HK1 cells and EBV-positive C666.1 NPC cells. |
分子量 | 654.66 |
分子式 | C34H38O13 |
CAS No. | 697235-39-5 |
密度 | 1.45 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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