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TargetMol | Compound Library

抗胰腺癌化合物库现货

Anti-Pancreatic Cancer Compound Library

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产品编号 L2192

随着医学技术的进步,大部分癌症的生存率都在提高,例如乳腺癌,结直肠癌等肿瘤,近几十年来,生存率得到了大幅度的提升。但是,有一个例外,那就是胰腺癌,胰腺癌是一种发病隐匿,进展迅速,治疗效果和预后极差的消化道恶性肿瘤。胰腺癌的生存率一直停滞不前,胰腺癌的五年生存率只有5%至10%,绝大部分患者在诊断胰腺癌半年内死亡,由于生存率低,死亡率高,胰腺癌称为癌中之王。 为了满足胰腺癌研究客户的需求,TargeMol 收集了 2508 种与胰腺癌相关的化合物,作用于 KRas, MEK, ERK, RAF, PI3K, HER2, EGFR, JAK/STAT, IGF-1R, VEGF, TGFβ等胰腺癌相关靶点,助力胰腺癌治疗药物的开发。

TargetMol 的所有产品和服务仅用于科学研究,不能被用于人体,我们也不向个人提供产品和服务。

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产品编号 L2192

抗胰腺癌化合物库

规格

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
询价 & 定制

产品特点 产品特点

  • 2508种与胰腺癌相关的化合物,可以用于高通量和高内涵筛选;
  • 靶点含KRas, MEK, ERK, RAF, PI3K, HER2, EGFR, JAK/STAT, IGF-1R, VEGF, TGFβ等;
  • 部分化合物已上市或已进入临床期;
  • 详细的说明书,化合物结构、靶点信息、IC50值、活性描述等;
  • NMR、HPLC/LCMS等多种检测技术保证产品结构正确,纯度高,减少假阳性。

Packaging And Storage | TargetMol 包装和储存

  • 可选用DMSO耐受的96/384孔板或2D 条形码编码管;
  • 干粉蓝冰运输,DMSO溶液干冰运输;
  • 排布:96孔板:1st & 12th 空白对照,384孔板:1st & 2nd & 23th & 24th空白对照。

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Library Customization | TargetMol 化合物库组成

Apoptosis
Autophagy
NF-κB
PI3K
EGFR
CDK
COX
VEGFR
JAK
PPAR
Wnt/beta-catenin
mTOR
Akt
HDAC
STAT
Src
PARP
GSK-3
ERK
AMPK
FGFR
p38 MAPK
Antibacterial
Endogenous Metabolite
c-Met/HGFR
Raf
PDGFR
FLT
Kras
HER
TGF-beta/Smad
p53
MEK
c-Kit
JNK
MMP
IGF-1R
TNF
Reactive Oxygen Species
Ras
DNA-PK
Parasite
Bcr-Abl
S6 Kinase
Caspase
Tyrosine Kinases
ATM/ATR
Aurora Kinase
ALK
MAPK
IL Receptor
HIF/HIF Prolyl-Hydroxylase
DNA/RNA Synthesis
P450
Potassium Channel
Mdm2
Antibiotic
Ferroptosis
Pim
PDK
Gamma-secretase
STING
c-RET
HIV Protease
Mitophagy
Influenza Virus
HIF
Hedgehog/Smoothened
E1/E2/E3 Enzyme
Antifungal
PKC
BCL
Lipoxygenase
PD-1/PD-L1
PKA
Calcium Channel
Casein Kinase
PI4K
Dehydrogenase
FAK
NO Synthase
Prostaglandin Receptor
Nrf2
Trk receptor
IκB/IKK
NOS
Virus Protease
Topoisomerase
BTK
Chk
Epigenetic Reader Domain
Interleukin
Beta Amyloid
Rho
PDE
ROS
c-Fms
Tyrosinase
Sirtuin
TAM Receptor
HCV Protease
Phosphatase
HSV
Antioxidant
ROCK
SIK
PTEN
AChR
Sodium Channel
DYRK
Adrenergic Receptor
Mitochondrial Metabolism
Antifection
PGE Synthase
P-gp
Antiviral
GABA Receptor
5-HT Receptor
Syk
Microtubule Associated
Proteasome
ATPase
ADC Cytotoxin
Estrogen/progestogen Receptor
Adenosine Receptor
Tie-2
Aryl Hydrocarbon Receptor
CSF-1R
Drug Metabolite
Smo
CCR
TLR
Ephrin Receptor
PLK
Anti-infection
Carbonic Anhydrase
Integrin
TRP/TRPV Channel
IAP
RIP kinase
HSP
transporter
MELK
GPR
SGK
IRAK
MLK
Chloride channel
IFNAR
PERK
Histamine Receptor
GTPase
c-Myc
Estrogen Receptor/ERR
HBV
Serine Protease
Hck
Serine/threonin kinase
PYK2
LDL
AChE
Cannabinoid Receptor
cholecystokinin
ROS Kinase
Transferase
Histone Methyltransferase
DNA Alkylator/Crosslinker
BACE
NADPH
RAAS
Glutathione Peroxidase
MRP
Nucleoside Antimetabolite/Analog
Leukotriene Receptor
Glucocorticoid Receptor
Immunology/Inflammation related
NMDAR
Glucosidase
Opioid Receptor
DNA Alkylation
cAMP
CaMK
DUB
Androgen Receptor
Acyltransferase
Porcupine
SARS-CoV
LRRK2
Free radical scavengers
Decarboxylase
Retinoid Receptor
Phospholipase
Discoidin Domain Receptor (DDR)
NOD
NOD-like Receptor (NLR)
Proton pump
Dopamine Receptor
Histone Demethylase
Progesterone Receptor
ABC
cell cycle arrest
Glucokinase
UGT
FAAH
ACK
GluR
ATP Citrate Lyase
Lipid
Beta-Secretase
MNK
Histone Acetyltransferase
Pyroptosis
RSV
Reverse Transcriptase
Aromatase
DAPK
Gap Junction Protein
NADPH-oxidase
S1P Receptor
Melanin-concentrating Hormone Receptor (MCHR)
Adenylyl cyclase
NPC1L1
DHFR
ROR
YAP
Arginase
LPL Receptor
LTR
Na+/Ca2+ Exchanger
Reductase
RAR/RXR 
gp120/CD4
TOPK
VDA
OCT
Cysteine Protease
Liver X Receptor
FXR
iGluR
Myosin
IRE1
FLAP
PAFR
Haspin Kinase
Hexokinase
Monoamine Transporter
Guanylate cyclase
DPP-4
Fatty Acid Synthase
Thioredoxin
PAK
PAD
Epoxide Hydrolase
Thrombopoietin Receptor
DNA
BCRP
Aminopeptidase
ASK
hCE
PAI-1
Methionine Adenosyltransferase (MAT)
Hippo pathway
LPA Receptor
CRISPR/Cas9
Hydroxylase
Adenosine deaminase
DNA Methyltransferase
BMI-1
Sigma receptor
Thrombin
p97
CFTR
PKM
Kinesin

Keywords