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BHBM is an acylhydrazone with antifungal activity.1,2 It is active against C. neoformans in vitro (MIC80 = 1 μg/ml).2 BHBM (0.25, 1, and 4 μg/ml) inhibits the synthesis of glucosylceramide, which is essential to fungal cell division, in C. neoformans but not J774 murine macrophages.1
BHBM is an acylhydrazone with antifungal activity.1,2 It is active against C. neoformans in vitro (MIC80 = 1 μg/ml).2 BHBM (0.25, 1, and 4 μg/ml) inhibits the synthesis of glucosylceramide, which is essential to fungal cell division, in C. neoformans but not J774 murine macrophages.1
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 647 | 35日内发货 | |
5 mg | ¥ 1,980 | 35日内发货 | |
10 mg | ¥ 3,720 | 35日内发货 | |
25 mg | ¥ 8,480 | 35日内发货 |
产品描述 | BHBM is an acylhydrazone with antifungal activity.1,2 It is active against C. neoformans in vitro (MIC80 = 1 μg/ml).2 BHBM (0.25, 1, and 4 μg/ml) inhibits the synthesis of glucosylceramide, which is essential to fungal cell division, in C. neoformans but not J774 murine macrophages.1 |
体内活性 | In vivo, BHBM (1.2 mg/kg per day) increases survival in a mouse model of C. neoformans infection. |
分子量 | 333.18 |
分子式 | C15H13BrN2O2 |
CAS No. | 302807-84-7 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度信息 | DMSO: Soluble |
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