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Anti-DCD Monoclonal Antibody
产品编号 TMAZ-0265
别名 Dermcidin, Preproteolysin
Anti-DCD Monoclonal Antibody is a rabbit antibody targeting DCD. Anti-DCD Monoclonal Antibody can be used in ELISA, FACS.
Anti-DCD Monoclonal Antibody
Anti-DCD Monoclonal Antibody
产品编号 TMAZ-0265 别名 Dermcidin, Preproteolysin
Anti-DCD Monoclonal Antibody is a rabbit antibody targeting DCD. Anti-DCD Monoclonal Antibody can be used in ELISA, FACS.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μg | ¥ 725¥ 1,250 | 7日内发货 | |
| 50 μg | ¥ 870¥ 1,500 | 7日内发货 | |
| 100 μg | ¥ 1,217.42¥ 2,099 | 7日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-DCD Monoclonal Antibody is a rabbit antibody targeting DCD. Anti-DCD Monoclonal Antibody can be used in ELISA, FACS. |
| 别名 | Dermcidin, Preproteolysin |
| Ig Type | Rabbit monoclonal IgG |
| 交叉反应 | Human |
| 验证活性 | Flow cytometry analysis of DCD overexpressed 472F cells with TMAZ-0265, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| 应用 | ELISA, FACS |
| 推荐剂量 | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Single-pass type I membrane |
| 构建方式 | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of DCD protein. |
| 纯化方式 | Protein A Affinity Purified |
| 性状 | Liquid |
| 缓冲液 | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| 纯度 | > 95% as determined by SDS-PAGE. |
| 研究背景 | Found in sweat, has an antimicrobial activity during early bacterial colonization (PubMed: 11694882, PubMed: 23426625). The secreted peptide assembles into homohexameric complexes that can associate with and also insert into pathogen membranes (PubMed: 23426625). Once inserted in bacteria membranes forms anion channels probably altering the transmembrane potential essential for bacterial survival (PubMed: 23426625). Highly effective against E.coli, E.faecalis, S.aureus and C.albicans (PubMed: 11694882). Optimal pH and salt concentration resemble the conditions in sweat (PubMed: 11694882). Also exhibits proteolytic activity, cleaving on the C-terminal side of Arg and, to a lesser extent, Lys residues (PubMed: 17448443)|Promotes survival of neurons and displays phosphatase activity (PubMed: 9736629). It may bind IgG (PubMed: 9736629) |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Biotin/APC/PE/AF488/AF555/AF647 |
| 可提供抗体种类 | 1 |
| 免疫原 | DCD |
| 抗原种属 | Human |
| 基因ID | 117159 |
| Uniprot ID | |
| 研究领域 | Other Functions |
| 分子量 | 150 kDa |
存储&运输
| 储存方式 | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| 运输方式 | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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