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Anti-CD86 Monoclonal Antibody
产品编号 TMAZ-0050
别名 CTLA-4 counter-receptor B7.2, B70, BU63, FUN-1, T-lymphocyte activation antigen CD86, Activation B7-2 antigen
Anti-CD86 Monoclonal Antibody is a rabbit antibody targeting CD86. Anti-CD86 Monoclonal Antibody can be used in ELISA, FACS.
Anti-CD86 Monoclonal Antibody
Anti-CD86 Monoclonal Antibody
产品编号 TMAZ-0050 别名 CTLA-4 counter-receptor B7.2, B70, BU63, FUN-1, T-lymphocyte activation antigen CD86, Activation B7-2 antigen
Anti-CD86 Monoclonal Antibody is a rabbit antibody targeting CD86. Anti-CD86 Monoclonal Antibody can be used in ELISA, FACS.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μg | ¥ 693.1¥ 1,195 | 7日内发货 | |
| 50 μg | ¥ 831.72¥ 1,434 | 7日内发货 | |
| 100 μg | ¥ 1,164.06¥ 2,007 | 7日内发货 |
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浓度:0.39 mg/mL
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偶联与修饰
抗原信息
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| 产品描述 | Anti-CD86 Monoclonal Antibody is a rabbit antibody targeting CD86. Anti-CD86 Monoclonal Antibody can be used in ELISA, FACS. |
| 别名 | CTLA-4 counter-receptor B7.2, B70, BU63, FUN-1, T-lymphocyte activation antigen CD86, Activation B7-2 antigen |
| Ig Type | Rabbit monoclonal IgG |
| 交叉反应 | Human |
| 验证活性 | Flow cytometry analysis of CD86 overexpressed 293F cells with TMAZ-0050BI, which was counjucated with SA-PE (red). The WT 293F control is black line. |
| 应用 | ELISA, FACS |
| 推荐剂量 | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Single-pass type I membrane |
| 构建方式 | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of CD86 protein. |
| 纯化方式 | Protein A Affinity Purified |
| 性状 | Liquid |
| 缓冲液 | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| 纯度 | > 95% as determined by SDS-PAGE. |
| 研究背景 | Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4 (PubMed: 12196291). May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation (PubMed: 7527824). Also involved in the regulation of B cells function, plays a role in regulating the level of IgG(1) produced. Upon CD40 engagement, activates NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation (By similarity)|Interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation|(Microbial infection) Acts as a receptor for adenovirus subgroup B |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Biotin/APC/PE/AF488/AF555/AF647 |
| 可提供抗体种类 | 2 |
| 免疫原 | CD86 |
| 抗原种属 | Human |
| 基因ID | 942 |
| Uniprot ID | |
| 研究领域 | Immunology Research |
| 分子量 | 150 kDa |
存储&运输
| 储存方式 | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| 运输方式 | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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