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Anti-EFNB2 Monoclonal Antibody
产品编号 TMAZ-0210
别名 EPH-related receptor tyrosine kinase ligand 5, Ephrin-B2, HTK ligand
Anti-EFNB2 Monoclonal Antibody is a rabbit antibody targeting EFNB2. Anti-EFNB2 Monoclonal Antibody can be used in ELISA, FACS.
Anti-EFNB2 Monoclonal Antibody
Anti-EFNB2 Monoclonal Antibody
产品编号 TMAZ-0210 别名 EPH-related receptor tyrosine kinase ligand 5, Ephrin-B2, HTK ligand
Anti-EFNB2 Monoclonal Antibody is a rabbit antibody targeting EFNB2. Anti-EFNB2 Monoclonal Antibody can be used in ELISA, FACS.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μg | ¥ 725¥ 1,250 | 7日内发货 | |
| 50 μg | ¥ 870¥ 1,500 | 7日内发货 | |
| 100 μg | ¥ 1,217.42¥ 2,099 | 7日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-EFNB2 Monoclonal Antibody is a rabbit antibody targeting EFNB2. Anti-EFNB2 Monoclonal Antibody can be used in ELISA, FACS. |
| 别名 | EPH-related receptor tyrosine kinase ligand 5, Ephrin-B2, HTK ligand |
| Ig Type | Rabbit monoclonal IgG |
| 交叉反应 | Human |
| 验证活性 | Flow cytometry analysis of EFNB2 overexpressed 429F cells with TMAZ-0210, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| 应用 | ELISA, FACS |
| 推荐剂量 | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Single-pass type I membrane |
| 构建方式 | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of EFNB2 protein. |
| 纯化方式 | Protein A Affinity Purified |
| 性状 | Liquid |
| 缓冲液 | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| 纯度 | > 95% as determined by SDS-PAGE. |
| 研究背景 | Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons|(Microbial infection) Acts as a receptor for Hendra virus and Nipah virus |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Biotin/APC/PE/AF488/AF555/AF647 |
| 可提供抗体种类 | 1 |
| 免疫原 | EFNB2 |
| 抗原种属 | Human |
| 基因ID | 1948 |
| Uniprot ID | |
| 研究领域 | Cytokines |
| 分子量 | 150 kDa |
存储&运输
| 储存方式 | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| 运输方式 | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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