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Anti-EFNB2 Monoclonal Antibody

产品编号 TMAZ-0210
别名 EPH-related receptor tyrosine kinase ligand 5, Ephrin-B2, HTK ligand

Anti-EFNB2 Monoclonal Antibody is a rabbit antibody targeting EFNB2. Anti-EFNB2 Monoclonal Antibody can be used in ELISA, FACS.

Anti-EFNB2 Monoclonal Antibody

Anti-EFNB2 Monoclonal Antibody

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产品编号 TMAZ-0210 别名 EPH-related receptor tyrosine kinase ligand 5, Ephrin-B2, HTK ligand

Anti-EFNB2 Monoclonal Antibody is a rabbit antibody targeting EFNB2. Anti-EFNB2 Monoclonal Antibody can be used in ELISA, FACS.

规格价格库存数量
25 μg¥ 725¥ 1,2507日内发货
50 μg¥ 870¥ 1,5007日内发货
100 μg¥ 1,217.42¥ 2,0997日内发货
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产品介绍

生物活性
产品描述
Anti-EFNB2 Monoclonal Antibody is a rabbit antibody targeting EFNB2. Anti-EFNB2 Monoclonal Antibody can be used in ELISA, FACS.
别名EPH-related receptor tyrosine kinase ligand 5, Ephrin-B2, HTK ligand
Ig Type
Rabbit monoclonal IgG
交叉反应
Human
验证活性
Flow cytometry analysis of EFNB2 overexpressed 429F cells with TMAZ-0210, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
应用
ELISA, FACS
推荐剂量
0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Single-pass type I membrane
构建方式This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of EFNB2 protein.
纯化方式Protein A Affinity Purified
性状Liquid
缓冲液0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin.
纯度> 95% as determined by SDS-PAGE.
研究背景Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons|(Microbial infection) Acts as a receptor for Hendra virus and Nipah virus
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Biotin/APC/PE/AF488/AF555/AF647
可提供抗体种类
1
抗原信息
免疫原
EFNB2
抗原种属
Human
基因ID
1948
Uniprot ID
研究领域
Cytokines
化学信息
分子量150 kDa
存储&运输
储存方式For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze.
运输方式For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice.

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