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Anti-CXADR Monoclonal Antibody
产品编号 TMAZ-0258
别名 CVB3-binding protein, HCVADR, Coxsackievirus and adenovirus receptor, Coxsackievirus B-adenovirus receptor
Anti-CXADR Monoclonal Antibody is a rabbit antibody targeting CXADR. Anti-CXADR Monoclonal Antibody can be used in ELISA, FACS.
Anti-CXADR Monoclonal Antibody
Anti-CXADR Monoclonal Antibody
产品编号 TMAZ-0258 别名 CVB3-binding protein, HCVADR, Coxsackievirus and adenovirus receptor, Coxsackievirus B-adenovirus receptor
Anti-CXADR Monoclonal Antibody is a rabbit antibody targeting CXADR. Anti-CXADR Monoclonal Antibody can be used in ELISA, FACS.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μg | ¥ 725¥ 1,250 | 7日内发货 | |
| 50 μg | ¥ 870¥ 1,500 | 7日内发货 | |
| 100 μg | ¥ 1,217.42¥ 2,099 | 7日内发货 |
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产品介绍
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偶联与修饰
抗原信息
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| 产品描述 | Anti-CXADR Monoclonal Antibody is a rabbit antibody targeting CXADR. Anti-CXADR Monoclonal Antibody can be used in ELISA, FACS. |
| 别名 | CVB3-binding protein, HCVADR, Coxsackievirus and adenovirus receptor, Coxsackievirus B-adenovirus receptor |
| Ig Type | Rabbit monoclonal IgG |
| 交叉反应 | Human |
| 验证活性 | Flow cytometry analysis of CXADR overexpressed 463F cells with TMAZ-0258, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| 应用 | ELISA, FACS |
| 推荐剂量 | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted |
| 构建方式 | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of CXADR protein. |
| 纯化方式 | Protein A Affinity Purified |
| 性状 | Liquid |
| 缓冲液 | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| 纯度 | > 95% as determined by SDS-PAGE. |
| 研究背景 | Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair|(Microbial infection) Acts as a receptor for adenovirus type C|(Microbial infection) Acts as a receptor for Coxsackievirus B1 to B6 |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Biotin/APC/PE/AF488/AF555/AF647 |
| 可提供抗体种类 | 1 |
| 免疫原 | CXADR |
| 抗原种属 | Human |
| 基因ID | 1525 |
| Uniprot ID | |
| 研究领域 | Other Functions |
| 分子量 | 150 kDa |
存储&运输
| 储存方式 | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| 运输方式 | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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