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M2I-1 是Mad2抑制剂,靶向的 Mad2 与 Cdc20 的结合,该结合是纺锤体装配检查点内必不可少的蛋白-蛋白相互作用。
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M2I-1 是Mad2抑制剂,靶向的 Mad2 与 Cdc20 的结合,该结合是纺锤体装配检查点内必不可少的蛋白-蛋白相互作用。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 248 | 现货 | |
5 mg | ¥ 579 | 现货 | |
10 mg | ¥ 892 | 现货 | |
25 mg | ¥ 1,880 | 现货 | |
50 mg | ¥ 2,970 | 现货 | |
100 mg | ¥ 4,970 | 现货 | |
500 mg | ¥ 9,870 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 693 | 现货 |
产品描述 | M2I-1 a small Mad2 inhibitor-1. the first small molecule inhibitor targeting the binding of Mad2 to Cdc20, an essential proteinprotein interaction (PPI) within the SAC. It can disturbs conformational dynamics of Mad2 critical for complex formation with Cdc20. It can also inhibited the Mad2-F-Mbp1 interaction in FP assays. |
别名 | M2I 1 |
分子量 | 404.48 |
分子式 | C19H24N4O4S |
CAS No. | 312271-03-7 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 45 mg/mL (111.25 mM) | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO
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