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Anti-SEMA4D Monoclonal Antibody
产品编号 TMAZ-0130
别名 BB18, Semaphorin-4D, GR3, A8
Anti-SEMA4D Monoclonal Antibody is a rabbit antibody targeting SEMA4D. Anti-SEMA4D Monoclonal Antibody can be used in ELISA, FACS.
Anti-SEMA4D Monoclonal Antibody
Anti-SEMA4D Monoclonal Antibody
产品编号 TMAZ-0130 别名 BB18, Semaphorin-4D, GR3, A8
Anti-SEMA4D Monoclonal Antibody is a rabbit antibody targeting SEMA4D. Anti-SEMA4D Monoclonal Antibody can be used in ELISA, FACS.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μg | ¥ 718.62¥ 1,239 | 7日内发货 | |
| 50 μg | ¥ 861.88¥ 1,486 | 7日内发货 | |
| 100 μg | ¥ 1,206.4¥ 2,080 | 7日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-SEMA4D Monoclonal Antibody is a rabbit antibody targeting SEMA4D. Anti-SEMA4D Monoclonal Antibody can be used in ELISA, FACS. |
| 别名 | BB18, Semaphorin-4D, GR3, A8 |
| Ig Type | Rabbit monoclonal IgG |
| 交叉反应 | Human |
| 验证活性 | Flow cytometry analysis of SEMA4D overexpressed 293F cells with TMAZ-0130BI, followed by goat anti-rabbit IgG-ABflo 647 (red). The isotype control is rabbit IgG (black line). |
| 应用 | ELISA, FACS |
| 推荐剂量 | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Single-pass type I membrane |
| 构建方式 | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of SEMA4D protein. |
| 纯化方式 | Protein A Affinity Purified |
| 性状 | Liquid |
| 缓冲液 | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| 纯度 | > 95% as determined by SDS-PAGE. |
| 研究背景 | Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling (PubMed: 20877282). Regulates GABAergic synapse development (By similarity). Promotes the development of inhibitory synapses in a PLXNB1-dependent manner (By similarity). Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA (PubMed: 19788569). Promotes the migration of cerebellar granule cells (PubMed: 16055703). Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro) (PubMed: 8876214). Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway (PubMed: 16055703) |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Biotin/APC/PE/AF488/AF555/AF647 |
| 可提供抗体种类 | 3 |
| 免疫原 | SEMA4D |
| 抗原种属 | Human |
| 基因ID | 10507 |
| Uniprot ID | |
| 研究领域 | Cancer Research |
| 分子量 | 150 kDa |
存储&运输
| 储存方式 | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| 运输方式 | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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