Abicipar pegol (AGN-150998, MP0112), an anti-VEGF DARPin molecule, represents a novel class of small ankyrin repeat domain-containing proteins designed for high specificity and affinity targeting. This compound is adept at inhibiting angiogenesis and vascular permeability. It has seen applicative use in ocular inflammation-related disease studies through intravitreal injections, notably decreasing mean retinal thickness and leakage area [1] [2].