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HSD17B13-IN-63 (Compound 160) 为一种羟基类固醇 17β-脱氢酶 13 (HSD17B13) 抑制剂,针对雌二醇展现出IC50值 ≤ 0.1 μM。该化合物适用于研究肝病、代谢性疾病或心血管疾病,例如非酒精性脂肪肝病(NAFLD)、非酒精性脂肪肝炎(NASH)以及药物性肝损伤(DILI)。
HSD17B13-IN-63 (Compound 160) 为一种羟基类固醇 17β-脱氢酶 13 (HSD17B13) 抑制剂,针对雌二醇展现出IC50值 ≤ 0.1 μM。该化合物适用于研究肝病、代谢性疾病或心血管疾病,例如非酒精性脂肪肝病(NAFLD)、非酒精性脂肪肝炎(NASH)以及药物性肝损伤(DILI)。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | HSD17B13-IN-63 (Compound 160) serves as an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) and demonstrates potent activity with an IC50 value of ≤ 0.1 μM against estradiol. This compound is utilized in research related to liver, metabolic, and cardiovascular diseases, including NAFLD, NASH, and drug-induced liver injury (DILI) [1]. |
分子量 | 589.30 |
分子式 | C24H15Cl2F5N4O4 |
CAS No. | 2770247-51-1 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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