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Topoisomerases/ribosomes-IN-1 (compound 30f) 作为核糖体和拓扑异构酶的抑制剂,展现出对抗大环内酯类耐药细菌的有效性。该化合物能够有效抑制细菌蛋白合成 (IC50: 0.647 μM) 和 DNA 复制 (IC50: 0.218 μM)。
Topoisomerases/ribosomes-IN-1 (compound 30f) 作为核糖体和拓扑异构酶的抑制剂,展现出对抗大环内酯类耐药细菌的有效性。该化合物能够有效抑制细菌蛋白合成 (IC50: 0.647 μM) 和 DNA 复制 (IC50: 0.218 μM)。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | Topoisomerases/ribosomes-IN-1 (compound 30f) serves as an inhibitor targeting both ribosomes and topoisomerases, specifically exhibiting inhibitory actions against constitutively macrolide-resistant bacteria. This compound effectively suppresses bacterial protein synthesis (IC 50 : 0.647 μM) and hampers DNA replication (IC 50 : 0.218 μM). |
分子量 | 1063.26 |
分子式 | C53H83FN6O15 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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