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Anti-IFNL2 Monoclonal Antibody is a rabbit antibody targeting IFNL2. Anti-IFNL2 Monoclonal Antibody can be used in ELISA, FACS.
Anti-IFNL2 Monoclonal Antibody is a rabbit antibody targeting IFNL2. Anti-IFNL2 Monoclonal Antibody can be used in ELISA, FACS.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 μg | ¥ 725¥ 1,250 | 7日内发货 | |
50 μg | ¥ 870¥ 1,500 | 7日内发货 | |
100 μg | ¥ 1,217.42¥ 2,099 | 7日内发货 |
产品描述 | Anti-IFNL2 Monoclonal Antibody is a rabbit antibody targeting IFNL2. Anti-IFNL2 Monoclonal Antibody can be used in ELISA, FACS. |
别名 | Interferon lambda-2, Interleukin-28A, Cytokine Zcyto20 |
Ig Type | Rabbit monoclonal IgG |
交叉反应 | Human |
验证活性 | Flow cytometry analysis of IFNL2 overexpressed 410F cells with TMAZ-0009, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
应用 | ELISA, FACS |
推荐剂量 | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
亚细胞定位 | Secreted |
构建方式 | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of IFNL2 protein. |
纯化方式 | Protein A Affinity Purified |
性状 | Liquid |
缓冲液 | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
纯度 | > 95% as determined by SDS-PAGE. |
研究背景 | Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression |
偶联 | Unconjugated |
其他可选修饰符 | Biotin/APC/PE/AF488/AF555/AF647 |
可提供抗体种类 | 2 |
免疫原 | IFNL2 |
抗原种属 | Human |
基因ID | 282616 |
Uniprot ID | |
研究领域 | Immunology Research |
分子量 | 150 kDa |
储存方式 | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
运输方式 | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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