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Search Results for " 7α-hydroxylase "
Targets Recommended: Others

4

抑制剂 & 化合物

1

天然产物

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Cat. No. Product Name Target Signaling Pathways
T11490 GSK2945

Others Others
GSK2945 is a highly specific Rev-erbα/REV-ERBα (mouse/human reverse erythroblastosis virus α) antagonist (EC50s: 21.5 μM and 20.8 μM). It enhances cholesterol -hydroxylase (CYP7A1) level and cholesterol metabolism.
T11490L GSK2945 hydrochloride (1438071-12-5 free base)

GSK2945 hydrochloride

Others Others
GSK2945 hydrochloride is a highly specific Rev-erbα/REV-ERBα (mouse/human reverse erythroblastosis virus α) antagonist (EC50s: 21.5 μM and 20.8 μM). It enhances cholesterol -hydroxylase (CYP7A1) level and cholesterol metabolism.
T62852 GSK2945 hydrochloride

Others Others
GSK2945 hydrochloride 是一种叔胺,是一种高特异性的 Rev-erbα/REV-ERBα(小鼠/人反向成红细胞病病毒α) 拮抗剂,他们的 EC50 值分别为 21.5 μM 和 20.8 μM。GSK2945 hydrochloride 能够提高胆固醇 -羟化酶 (CYP7A1) 水平和胆固醇代谢。
T84963 5α-Androstan-3β-ol

NSC 50887

Others Others
5α-Androstan-3β-ol, a steroidal androgen, demonstrates selective interaction with cellular components, showing affinity for the androgen receptor (AR) with an IC50 of 1.7 µM and activating the pregnane X receptor (PXR) in HepG2 cells with an EC50 of 0.8 µM. It selectively inhibits the hydroxylase activities of 16α- and 6β-hydroxylase over 16β- or -hydroxylase, with IC50 values of 70 and 110 µM, compared to >150 µM for the latter enzymes, indicating a specificity in its enzyme inhibition profil...

化合物

GSK2945
Cat.No: T11490
Synonym:
Target: Others
GSK2945 hydrochloride (1438071-12-5 free base)
Cat.No: T11490L
Synonym: GSK2945 hydrochloride
Target: Others
GSK2945 hydrochloride
Cat.No: T62852
Synonym:
Target: Others
5α-Androstan-3β-ol
Cat.No: T84963
Synonym: NSC 50887
Target: Others
Cat. No. Product Name Target Signaling Pathways
T8153 glycohyodeoxycholic acid

Others; Endogenous Metabolite Metabolism; Others
Glycohyodeoxycholic acid 是一种人体次级胆汁酸猪去氧胆酸的主要代谢物,能够预防胆结石的形成。

天然产物

glycohyodeoxycholic acid
Cat.No: T8153
Synonym:
Target: Others, Endogenous Metabolite
TargetMol Loading
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